Adams Nance syndrome


Adams Nance syndrome is a medical condition consisting of persistent tachycardia, paroxymal hypertension and seizures. It is associated with hyperglycinuria, dominantly inherited microphthalmia and cataracts. It is thought to be caused by a disturbance in glycine metabolism.


  • Cardiac conduction defects
  • Cataract
  • Kidney stones
  • Abnormal metabolism of amino acids
  • Small eyes
  • Rapid heartbeat
  • High blood pressure
  • The presence of excess glycine in the urine
  • Seizures
  • Severe loss of vision
  • Rapid heart rate
  • Glaucoma
  • Protruding eyes
  • Nystagmus
  • Xanthomas
  • Fainting