Diseases

Hemangioendothelioma

Hemangioendothelioma is used to describe a group of vascular neoplasms that may be considered benign or malignant in their activity.

Hemangioma thrombocytopenia syndrome

A rare condition characterized by a spreading congenital hemangioma (collection of abnormal blood vessels) usually on the skin as well as blood clotting problems.

Hemangioma- capillary infantile

A dull red, firm, dome-shaped hemangioma, sharply demarcated from surrounding skin, usually located on the head and neck, which grows rapidly and generally undergoes regression and involution without scarring. It is caused by proliferation of immature capillary vessels in active stroma, and is usually present at birth or occurs within the first two or three months of life.

Hemangiopericytoma

Hemangiopericytomas are rare vascular tumors that arise from pericytes, which are cells that are associated with capillary walls. These tumors can originate anywhere in the body there are capillaries, which is virtually everywhere. The most common locations reported are the lower extremities, pelvic area, head, and neck. They occur in all ages and equally in both sexes. They can be either benign or malignant, and can metastasize, with the most common sites being the lungs and bones.

Hemeralopia- familial

A rare familial disorder where a person can only see when the light is faint or absent. Sufferers are unable to see in bright light and thus daytime vision is poor but nighttime vision is good.

Hemi 3 syndrome

A very rare syndrome where parts of the body undergo excessive growth give the body an asymmetrical appearance.

Hemifacial hyperplasia strabismus

Hemifacial hyperplasia strabismus is a rare inherited condition characterized mainly by abnormal, asymmetrical facial bone growth and eye problems in some cases.

Hemimegalencephaly

Hemimegalencephaly is a rare neurological condition in which one-half of the brain, or one side of the brain, is abnormally larger than the other. As a consequence of this imbalance, the unusual and enlarged brain tissue causes frequent seizures, usually followed with mental retardation. Hemimegalencephaly may occur as an isolated finding in an infant or it may be associated with other syndromes.

Hemiplegia

Hemiplegia is a condition in which one-half of a patient's body is paralyzed. Hemiplegia is more severe than hemiparesis, wherein one half of the body is weakened but not paralysed

Hemiplegic migraine- familial type 1

A rare inherited form of migraine that characteristically causes temporary paralysis on one side of the body and involves the presence of an aura. A migraine episode may be triggered by minimal trauma to the head. The severity of the disorder is variable with some patients experiencing paralysis on one side of the body or coma for weeks.

Hemoglobinopathy

Hemoglobinopathy is a group of disorders passed down through families (inherited) in which there is abnormal production or structure of the hemoglobin molecule. Such disorders include hemoglobin C disease, hemoglobin S-C disease, sickle cell anemia, and various types of thalassemia.

Hemoglobinuria

Alternative Names: Urine - hemoglobin Hemoglobin is a molecule attached to red blood cells that helps move oxygen and carbon dioxide through the body. Red blood cells have an average life span of 120 days. After this time, they are broken down into parts that can make a new red blood cell. This typically takes place in the spleen, bone marrow, and liver. If the red blood cells break down the blood vessels, their parts move freely in the bloodstream. If the level of hemoglobin in the blood rises too high, then hemoglobin begins to appear in the urine. This is called hemoglobinuria. This article focuses on the urine test done to diagnose hemoglobinuria.

Hemolytic Disease of the Fetus and Newborn

 

Hemolytic disease of the fetus and newborn (HDFN) is a blood disorder that causes your baby’s red blood cells to break down quickly. When red blood cells break down it is called hemolysis.

Hemolytic Disease of the Fetus and Newborn

Hemolytic disease of the fetus and newborn (HDFN) is a blood disorder that causes your baby’s red blood cells to break down quickly. When red blood cells break down it is called hemolysis. Hemolysis causes anemia (low number of red blood cells) and jaundice (an increased bilirubin level) during the first few days to weeks of your baby’s life. Severe anemia can cause critical illness since it is harder to deliver oxygen throughout the body. This type of severe jaundice can lead to hearing problems/deafness and brain damage if left untreated. HDFN occurs when there is a mismatch between the mother’s and baby’s blood type and/or Rh factor during pregnancy.

Hemolytic uremic syndrome- atypical- childhood

Hemolytic uremic syndrome, atypical, childhood: A rare disorder involving destruction of blood cells and kidney disease. Unlike typical hemolytic uremic syndrome which usually follows a bacterial infection, the atypical form is possibly a genetic disorder. The distinguishing feature of the atypical form is that no diarrhea is involved. The atypical form has a poorer prognosis than the typical form.

Hemolytic-uremic syndrome

Hemolytic uremic syndrome HUS  is a condition caused by the abnormal destruction of red blood cells. The damaged red blood cells clog the filtering system in the kidneys, which can lead to life-threatening kidney failure.

HUS usually develops in children after five to 10 days of diarrhea, often bloody, caused by infection with certain strains of Escherichia coli (E. coli) bacteria. Adults also can develop HUS due to E. coli or other types of infection, certain medications, or pregnancy. HUS is a serious condition. But timely and appropriate treatment leads to a full recovery for most people, especially young children.

Hemolytic uremic syndrome should be distinguished from atypical hemolytic uremic syndrome (aHUS). The two conditions have different causes and different signs and symptoms.

Hemophagocytic lymphohistiocytosis

Hemophagocytic lymphohistiocytosis (HLH), is an uncommon hematologic disorder. It is a life-threatening disease of severe hyperinflammation caused by uncontrolled proliferation of activated lymphocytes and macrophages characterised by proliferation of morphologically benign lymphocytes and macrophages that secrete high amounts of inflammatory cytokines. It is classified as one of the cytokine storm syndromes.

Hemophagocytic lymphohistiocytosis- familial- 2

Hemophagocytic lymphohistiocytosis, familial, 2: A rare recessively inherited disorder involving an overactive immune system. More specifically, the body becomes infiltrated by large numbers of histiocytes (macrophages) that accumulate in various organs such as the liver, spleen, bone marrow, skin and central nervous system. It usually only occurs in infants and young children. Type 2 is caused by a defect on chromosome 10q22.

Hemophagocytic lymphohistiocytosis- familial- 3

Hemophagocytic lymphohistiocytosis, familial, 3: A rare recessively inherited disorder involving an overactive immune system. More specifically, the body becomes infiltrated by large numbers of histiocytes (macrophages) that accumulate in various organs such as the liver, spleen, bone marrow, skin and central nervous system. It usually only occurs in infants and young children. Type 3 is caused by a defect on chromosome 17q25.1.

Hemophagocytic lymphohistiocytosis- familial- 4

Hemophagocytic lymphohistiocytosis, familial, 4: A rare recessively inherited disorder involving an overactive immune system. More specifically, the body becomes infiltrated by large numbers of histiocytes (macrophages) that accumulate in various organs such as the liver, spleen, bone marrow, skin and central nervous system. It usually only occurs in infants and young children. Type 4 is caused by a defect on chromosome 6q24.

Hemophagocytic reticulosis

Hemophagocytic reticulosis: The abnormal proliferation of reticulum cell (histiocytes) which infiltrate various organs and. Macrophages destroy blood cells causing blood abnormalities. Meningoencephalitis frequently occurs when the histiocytes infiltrate the mininges and cerebral tissue. Symptoms start at birth or soon after and become progressively worse without treatment. Medication can control the condition but a hematopoietic stem cell transplant is needed to achieve remission.

Hemophilia A

Hemophilia A is a bleeding disorder in which the blood does not clot normally. People with this disorder have prolonged bleeding or oozing after an injury, surgery, or tooth extraction. In severe cases, heavy bleeding occurs after minor injury or even when there is no injury (spontaneous bleeding). Serious complications can result from bleeding into the joints, muscles, brain, or other internal organs. In milder forms there is no spontaneous bleeding, and the disorder may not become apparent until after a surgery or serious injury.

The major types of this condition are hemophilia A (also known as classic hemophilia or factor VIII deficiency) and hemophilia B (also known as Christmas disease or factor IX deficiency). Although the two types have very similar signs and symptoms, they are caused by mutations in different genes. 

Hemophilia A- congenital

Hemophilia is a rare inherited blood clotting (coagulation) disorder caused by inactive or deficient blood proteins (usually factor VIII). Factor VIII is one of several proteins that enable the blood to clot. Hemophilia may be classified as mild, moderate, or severe. The level of severity is determined by the percentage of active clotting factor in the blood (normal percentage ranges from 50 to 150 percent). People who have severe hemophilia have less than one percent of active clotting factor in their blood. hemophilia A (also known as classical hemophilia, factor VIII deficiency or antihemophilic globulin [AHG] deficiency);