Diseases

Groll Hirschowitz syndrome

Groll-Hirschowitz syndrome: A rare genetic condition characterized by deafness, gastrointestinal abnormalities and neuropathy.

Grosse syndrome

Wiedemann Grosse Dibbern syndrome (medical condition): A syndrome which is characterised by the association of symptoms such as abnormal facies, short stature, and psychomotor retardation.

Group B strep disease in newborns

Group B streptococcus (GBS) is a bacterium that can be found in the digestive tract, urinary tract, and genital area of adults. Although GBS infection usually does not cause problems in healthy women before pregnancy, it can cause serious illness for the mother and baby during pregnancy and after delivery.

Grover’s disease

Grover's disease, or Transient Acantholytic Dyskeratosis (TAD), is a relatively common skin disease characterized by small red, bumpy spots

Growth hormone deficiency

Growth Hormone Deficiency (GHD) is a medical condition in which the body does not produce enough growth hormone (GH). Growth hormone, also called somatotropin, is a polypeptide hormone which stimulates growth and cell reproduction. HGH also refers to human growth hormone but this older abbreviation has begun to develop paradoxical connotations, particularly in relation to the peddling of medically unnecessary GH supplementation (so-called HGH quackery).
There are a variety of rare diseases which resemble GH deficiency, including the childhood growth failure, facial appearance, delayed bone age, and low IGF levels.

Growth mental deficiency syndrome of Myhre

Myhre syndrome is an extremely rare inherited disorder characterized by mental retardation, short stature, unusual facial features, and various bone (skeletal) abnormalities

GTP cyclohydrolase deficiency

A rare metabolic disorder caused by an enzyme deficiency (GTP cyclohydrolase) which causes a harmful build up of phenylalanine in the blood.

Guanidinoacetate methyltransferase deficiency

A rare disorder of amino acid metabolism where glycine and proline are unable to be metabolized properly due to deficiency of the enzyme called guanidinoacetate methyltransferase.

Guillain-Barré syndrome

Guillain–Barré syndrome ( Landry's paralysis, acute idiopathic polyneuritis) is a rapid-onset muscle weakness as a result of damage to the peripheral nervous system. Many experience changes in sensation or develop pain, followed by muscle weakness beginning in the feet and hands. The symptoms develop over half a day to two weeks. During the acute phase, the disorder can be life-threatening with about a quarter developing weakness of the breathing muscles and requiring mechanical ventilation. Some are affected by changes in the function of the autonomic nervous system, which can lead to dangerous abnormalities in heart rate and blood pressure.

This autoimmune disease is caused by the body's immune system mistakenly attacking the peripheral nerves and damaging their myelin insulation. Sometimes this immune dysfunction is triggered by an infection. The diagnosis is usually made on based on the signs and symptoms, through the exclusion of alternative causes, and supported by tests such as nerve conduction studies and examination of the cerebrospinal fluid. Various classifications exist, depending on the areas of weakness, results of nerve conduction studies, and the presence of antiganglioside antibodies. It is classified as an acute polyneuropathy.

Gusher syndrome

An inherited form of progressive deafness affecting mostly males. It results from a congenital malformation of the inner ear structures

Gynandroblastoma

A type of ovarian tumor that causes feminizing and masculinizing effects of estrogen and androge

Haemophilus influenzae

Haemophilus influenzae, formerly called Pfeiffer's bacillus or Bacillus influenzae, is a non-motile Gram-negative coccobacillus first described in 1892 by Richard Pfeiffer during an influenza pandemic. A member of the Pasteurellaceae family, it is generally aerobic, but can grow as a facultative anaerobe.[1] H. influenzae was mistakenly considered to be the cause of influenza until 1933, when the viral etiology of the flu became apparent. Still, H. influenzae is responsible for a wide range of clinical diseases.

Haff disease

Haff disease or Haff syndrome is the development of rhabdomyolysis (swelling and breakdown of skeletal muscle, with a risk of acute kidney failure) within 24 hours of ingesting fish.

It was first described in 1924 in the vicinity of Königsberg, Germany (now Kaliningrad, Russia) on the Baltic coast, in people staying around the haff (German: lagoon).Over the subsequent fifteen years, about 1000 cases were reported in people, birds and cats, usually in the summer and fall, and a link was made with the consumption of fish (burbot, eel and pike). Since that time, only occasional reports have appeared of the condition, mostly from the Soviet Union and Germany.

In 1997, six cases of Haff disease were reported in California and Missouri, all after the consumption of buffalo fish (Ictiobus cyprinellus). In July and August 2010, dozens of people contracted rhabdomyolysis after eating Procambarus clarkii in Nanjing, China. A month later, the Chinese authorities claimed they were victims of Haff disease.

The most recent US outbreak was reported in Brooklyn, NY on 18 November 2011, when two household members were stricken by the syndrome after eating Buffalo fish.

Hagemoser Weinstein Bresnick syndrome

Hagemoser Weinstein Bresnick syndrome is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Hagemoser Weinstein Bresnick syndrome, or a subtype of Hagemoser Weinstein Bresnick syndrome, affects less than 200,000 people in the US population.

Hailey Hailey disease

Hailey-Hailey disease, or familial benign pemphigus, was originally described by the Hailey brothers in 1939.[1][2] It is a genetic disorder that causes blisters to form on the skin.

Haim-Munk syndrome

Haim-Munk syndrome is an extremely rare genetic disorder similar to Papillion-Lefevre syndrome. Features include callous patches of skin on the palms of the hands and the soles of the feet, long pointy fingers, and degeneration of the tissues that surround and support the teeth.

HAIR-AN syndrome

A very rare syndrome that affects females only and is characterized mainly by insulin resistance, dark velvety patches of skin and increased male hormone production in females.

Hairy cell leukemia

Hairy cell leukemia is a rare, slow-growing cancer of the blood in which the bone marrow produces too many B cells (lymphocytes), a type of white blood cell that fights infection. The condition is named after these excess B cells which look 'hairy' under a microscope because of fine projections (villi) from their surface. As the number of leukemia cells increases, fewer healthy white blood cells, red blood cells and platelets are produced.

Hairy cell leukemia affects more men than women, and it occurs most commonly in middle-aged or older adults. Hairy cell leukemia is considered a chronic disease because it may never completely disappear, although treatment can lead to a remission for years.

Hairy elbows

A rare condition where the elbows become progressively hairy until about 5 years of age and then slowly disappears. Short stature appears to be associated in the some of the few cases reported.