Use of Platelet-enriched Plasma During Auricular Reconstruction
Use of Platelet-enriched Plasma to Improve the Percentage of Integration of the Cutaneous Graft During Second Stage of Auricular Reconstruction in Children Aged 8-12 Years; A Controlled Clinical Trial
In this study investigators are trying to determine the benefits of using platelet enriched
plasma during the second stage of auricular reconstruction. The intervention will be blinded
to the surgeon and the surgical team. The main outcome will be the evaluation of the
integration rate of the skin full thickness graft used to coat the auricular frame.
Integration rate (in percentage) of the full thickness split graft sued during the second stage of auricular reconstruction.
Platelet enriched plasma administration
Study Arms / Comparison Groups
Description: In this arm, surgeon will be applying platelet enriched plasma(PEP) (5 ml) during the second stage procedure of auricular reconstruction. PEP will be infected in the temporal fascia used to cover the cartilage frame.
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
June 29, 2017
December 10, 2018
Primary Completion Date
November 29, 2018
- Microtia Tanzer II-A
- patients aged 8-12 years
- Haemoglobin > 10 gr/dL
- History of first stage of auricular reconstruction
- associated endocrinopathies
- desnutrition (<2.5 gr/ dL)