The Relationships Between Gene Polymorphisms of LTA4H and Dexamethasone Treatment for Tuberculous Meningitis

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Brief Title

The Relationships Between Gene Polymorphisms of LTA4H and Dexamethasone Treatment for Tuberculous Meningitis


Brief Summary

      The study aimed to evaluate the relationships between the gene polymorphisms of leukotriene
      A4 hydrolase(LTA4H) and Dexamethasone treatment for tuberculous meningitis in Chinese
      patients.
    


Study Phase

Phase 4

Study Type

Interventional


Primary Outcome

MRI


Condition

Tuberculous Meningitis

Intervention

Dexamethasone acetate

Study Arms / Comparison Groups

 treatment of dexamethasone group
Description:  

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information


Recruitment Status

Drug

Estimated Enrollment

200

Start Date

November 2015


Primary Completion Date

October 2018

Eligibility Criteria

        Inclusion Criteria:

        patients were eligible to enter the study if they met the diagnositic criteria for
        possible, probable or definite Tuberculosis meningitis(TBM).

        Exclusion Criteria:

        Patients were excluded if they were infected with HIV, diagnosed as carcinomatous
        meningitis, viral meningitis, purulent meningitis, cryptococcus meningitis.
      

Gender

All

Ages

14 Years - N/A


Contacts

, , 



Administrative Informations


NCT ID

NCT02588196

Organization ID

BH 002


Responsible Party

Sponsor-Investigator

Study Sponsor

Hui Bu


Study Sponsor

, , 


Verification Date

October 2015