the Effect of Oral Vasopressors for Liberation From IV Vasopressors in Spinal Shock

Brief Title

the Effect of Oral Vasopressors for Liberation From IV Vasopressors in Spinal Shock

Official Title

The Effect of Oral Midodrine Versus Oral Desmopressin Acetate Use for Liberation From IV Noradrenaline in Intensive Care Unit Patients Recovering From Spinal Shock .

Brief Summary

      the study is developed to evaluate the effect of use of oral vasopressors (midodrine versus
      minirin) on weaning ICU patients from IV vasopressors (noradrenaline) and compare between
      them for efficacy in shortage the duration of IV vasopressor and has low complications and
      side effects.
    


Study Phase

Phase 2

Study Type

Interventional


Primary Outcome

liberation the patient from IV vasopressors with maintaining hemodynamics.


Condition

Spinal Shock

Intervention

Midodrine Oral Tablet

Study Arms / Comparison Groups

 midodrine group
Description:  midodrine group will receive midodrine 10 mg PO q8hr with gradual weaning of IV noradrenaline after receiving 4 doses of oral midodrine

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information


Recruitment Status

Drug

Estimated Enrollment

90

Start Date

October 15, 2020

Completion Date

January 28, 2021

Primary Completion Date

January 1, 2021

Eligibility Criteria

        Inclusion Criteria:

          -  Age of 18 - 60 years.

          -  Patients of both genders.

          -  Patients diagnosed by spinal shock and they are in the recovery stage .

        Exclusion Criteria:

          -  Patient refusal.

          -  Anuric or oliguric patients or patients with chronic kidney disease.

          -  Patients with allergy to medication included in the study.
      

Gender

All

Ages

18 Years - 60 Years

Accepts Healthy Volunteers

No

Contacts

Ahmed T Ahmed, lecture, 01062716629, [email protected]

Location Countries

Egypt

Location Countries

Egypt

Administrative Informations


NCT ID

NCT04586790

Organization ID

oral vasopressors


Responsible Party

Sponsor-Investigator

Study Sponsor

Ahmed talaat ahmed aly


Study Sponsor

Ahmed T Ahmed, lecture, Principal Investigator, Assiut University


Verification Date

October 2020