Spontaneous Coronary Artery Dissection National Swiss Registry

Brief Title

Spontaneous Coronary Artery Dissection National Swiss Registry

Official Title

Spontaneous Coronary Artery Dissection (SCAD) National Swiss Registry (SwissSCAD)

Brief Summary

      Spontaneous coronary artery dissection (SCAD), is an underdiagnosed pathology, affecting
      predominantly young women without traditional cardiovascular risk factors and is associated
      with major adverse outcomes including myocardial infarction, cardiac arrest, or death.

      Timely diagnosis of SCAD as well as clinical follow-up are of the essence in this pathology
      associated with major cardiac adverse outcomes. Despite recent improvements in diagnosis and
      recognition of the importance of SCAD, it remains poorly studied and understood.

      In this context, we designed the SwissSCAD registry, a large, observational, prospective,
      cohort study, to describe the natural history of SCAD, its outcomes and its treatments.
    



Study Type

Observational [Patient Registry]


Primary Outcome

Primary objective


Condition

Spontaneous Coronary Artery Dissection


Study Arms / Comparison Groups

 Retrospective patients
Description:  The investigators will review the hospital records at the investigational site for SCAD events having occurred over the last 5 years. All SCAD patients aged ≥18 years, not presenting atherosclerotic or iatrogenic coronary dissection will be informed about the SwissSCAD study by phone and will be given at least one week to decide if they wish to participate. We plan to include 500 patients in the retrospective arm.

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information



Estimated Enrollment

1000

Start Date

June 30, 2020

Completion Date

June 30, 2030

Primary Completion Date

June 30, 2025

Eligibility Criteria

        Inclusion Criteria:

          -  Subject is ≥18 years of age.

          -  Patient presenting newly diagnosed SCAD or diagnosed with SCAD within the last 5
             years.

          -  Subject must be willing to sign a Patient Informed Consent (PIC).

        Exclusion Criteria:

          -  Patient unwilling or unable to provide informed consent.

          -  Patients with atherosclerotic or iatrogenic coronary dissection.
      

Gender

All

Ages

18 Years - N/A


Contacts

Sophie Degrauwe, Dr, +41795530294, [email protected]

Location Countries

Switzerland

Location Countries

Switzerland

Administrative Informations


NCT ID

NCT04457544

Organization ID

2019-01886


Responsible Party

Sponsor-Investigator

Study Sponsor

Dr. Sophie Degrauwe


Study Sponsor

Sophie Degrauwe, Dr, Principal Investigator, Hopitaux universitaires de Geneve


Verification Date

June 2020