Peri Kasai Portoenterostomy Anchoring of the Jejunal Loop

Brief Title

Peri Kasai Portoenterostomy Anchoring of the Jejunal Loop


Brief Summary

      the study of the effect o the hanging of the jejunal loop to the peri KPE Glisson capsule on
      the rate of bile drainage and requirement of liver transplantation
    

Detailed Description

      To evaluate the effect of anchoring jejunal loop to Glisson capsule of liver after completion
      of modified Kasai portoenterostomy (KPE) on the frequency of attacks of cholangitis and the
      overall incidence of native liver survival.

      Methods: Retrospective study included 29 infants diagnosed as biliary atresia (BA). They were
      subjected to modified KPE. Two subgroups were present. Group A included 16 infants and had
      KPE. Group B included 13 infants and had the assumed modification. Wider dissection of
      fibrous portal plate was considered in both groups. After completion of KPE, the jejunal loop
      anchored to Glisson capsule of liver at porta hepatis in group B.
    


Study Type

Interventional


Primary Outcome

decrease he total number of cholangitis

Secondary Outcome

 early improvement of liver functions

Condition

Biliary Atresia

Intervention

kasai portoenterostomy

Study Arms / Comparison Groups

 classic KPE
Description:  the classic management of biliary atresia as described

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information


Recruitment Status

Procedure

Estimated Enrollment

26

Start Date

January 2015

Completion Date

December 2021

Primary Completion Date

June 2021

Eligibility Criteria

        Inclusion Criteria:

          -  infants with biliary atresia diagnosed and treated before 60th day of age

        Exclusion Criteria:

          -  infants older than 60 days
      

Gender

All

Ages

N/A - 8 Weeks

Accepts Healthy Volunteers

No

Contacts

, +201003546853, [email protected]

Location Countries

Egypt

Location Countries

Egypt

Administrative Informations


NCT ID

NCT04961034

Organization ID

33943/7/20


Responsible Party

Principal Investigator

Study Sponsor

Tanta University


Study Sponsor

, , 


Verification Date

July 2021