Natural History of Urticaria Pigmentosa in Children

Brief Title

Natural History of Urticaria Pigmentosa in Children

Official Title

Natural History of Urticaria Pigmentosa in Children

Brief Summary

      The purpose of this study is to determine how long the skin lesions usually last and what
      kind of symptoms and signs children with urticaria pigmentosa may develop over the years.
      This information will allow physicians to better care for patients who have been diagnosed
      with this disease and to provide their parents with more complete information regarding what
      to expect for the future of their child. This research is being done because many unanswered
      questions remain regarding children with urticaria pigmentosa and its course.
    

Detailed Description

      This study involves children, of age 0-18 years old who are diagnosed with urticaria
      pigmentosa during their visit at the Pediatric Dermatology Clinic. Parents and child will be
      interviewed to gain medical and family history, in addition, the doctor will perform a
      physical exam and take a photograph. Children older than 4 years of age will complete the
      "Children Dermatology Life Quality Index." Children less than 4 years of age with an active
      disease will have laboratory tests requiring a sample of blood (1 teaspoon).

      Patients will receive $50 for their first office visit as financial reimbursement for
      participating in the study.
    


Study Type

Observational




Condition

Urticaria Pigmentosa



Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information



Estimated Enrollment

47

Start Date

January 2006

Completion Date

June 2008

Primary Completion Date

June 2008

Eligibility Criteria

        Inclusion Criteria:

          -  Age 0-18 years old at diagnosis of UP

          -  3 or more mastocytomas (diagnosis can be based on clinical exam; biopsy only necessary
             if diagnosis is in question)

          -  patients recruited from Children's Hospital of Wisconsin Dermatology Clinic

        Exclusion Criteria:

          -  Less than 3 mastocytomas

          -  Diffuse mastocytosis

          -  TMEP

          -  residence is out of Wisconsin/Illinois area or the United States
      

Gender

All

Ages

N/A - 18 Years

Accepts Healthy Volunteers

No

Contacts

Sheila Galbraith, MD, , 

Location Countries

United States

Location Countries

United States

Administrative Informations


NCT ID

NCT00467792

Organization ID

UP



Study Sponsor

Medical College of Wisconsin

Collaborators

 Society for Pediatric Dermatology

Study Sponsor

Sheila Galbraith, MD, Principal Investigator, Medical College of Wisconsin


Verification Date

December 2008