Identification of New Markers in the Hypereosinophilic Syndrome

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Idiopathic hypereosinophilic syndrome
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Brief Title

Identification of New Markers in the Hypereosinophilic Syndrome

Official Title

Identification of New Markers in the Hypereosinophilic Syndrome

Brief Summary

      The purpose is to characterize new hypereosinophilic syndrome biomarkers more informative and
      more accessible compared to those that we have already thanks to a proteomic approach. This
      will help the investigators to diagnose the this disease.

Study Type

Interventional

Primary Outcome

The aim is to characterize, through an approach immunoprotéomique, new HES biomarkers more informative and easier access than those currently available to us. These biomarkers will help to the diagnosis of HES, compared with other causes of eosinophilia.

Condition

Hypereosinophilic Syndrome

Intervention

biologie sample

Study Arms / Comparison Groups

 Hypereosinophilic syndrome unexplained
Description:

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information

Recruitment Status

Biological

Estimated Enrollment

41

Start Date

June 29, 2010

Completion Date

July 2015

Primary Completion Date

July 2015

Eligibility Criteria

        Inclusion Criteria:

          -  dated and signed informed consent

          -  virale serology negative or negative result less than 6 months

          -  virale serology negative for HBV or vaccinated patient

          -  insured

          -  virale serology negative or negative result less than 6 months

          -  negative pregnancy test or female menopause for at least 1 year

        Exclusion Criteria:

          -  subject enable adult, under guardianship or under protective measures of justice

          -  Refusal or inability to give informed consent

          -  The hypereosinophilic syndrome explained origin other than than atopy, bullous
             pemphigoid, the Churg-Strauss syndrome and DRESS

Gender

All

Ages

18 Years - 80 Years

Accepts Healthy Volunteers

Accepts Healthy Volunteers

Contacts

Lionel Prin, MD PhD, ,

Location Countries

France

Location Countries

France

Administrative Informations

NCT ID

NCT01713504

Organization ID

2008_29

Secondary IDs

2009-A00314-53

Responsible Party

Sponsor

Study Sponsor

University Hospital, Lille

Study Sponsor

Lionel Prin, MD PhD, Principal Investigator, University Hospital, Lille

Verification Date

February 2019