Effect of High Protein Diet on Cardiovascular Diseases Risk Factors Among Overweight and Obese Children

Brief Title

Effect of High Protein Diet on Cardiovascular Diseases Risk Factors Among Overweight and Obese Children


Brief Summary

      The investigators aimed to determine the effects of HP diet on CVD risk factors among
      overweight and obese children.
    

Detailed Description

      Background: Studies regarding the effects of high protein (HP) diet on cardiovascular (CVD)
      risk factors have reported contradictory results.

      Objective: In present study, the investigators aimed to determine the effects of HP diet on
      CVD risk factors among overweight and obese children.

      Design: In this randomized controlled trial, the investigators recruited 50 overweight and
      obese women, aged 6-11years into HP or control energy restricted diets for 10 weeks (protein,
      carbohydrate, fat: 25%, 45%, 30% vs. 15%, 55%, 30%, respectively). Total protein amount,
      divided to animal and plant sources in 50%-50% and animal sources distributed (half/half)
      between meats and dairy products. Fasting blood samples, lipid profile, systolic and
      diastolic blood pressure and anthropometric measurements were measured based on the standard
      guidelines.
    

Study Phase

Phase 3

Study Type

Interventional


Primary Outcome

the amount of weight reduction in two dietary groups

Secondary Outcome

 LDL (mg/ml)

Condition

Body Mass Index Quantitative Trait Locus 7 Disorder

Intervention

nutrition intervention

Study Arms / Comparison Groups

 nutrition intervention
Description:  high protein diet

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information


Recruitment Status

Other

Estimated Enrollment

50

Start Date

September 2011

Completion Date

September 2012

Primary Completion Date

December 2011

Eligibility Criteria

        Inclusion Criteria:

          -  BMI > 85th age of 6-11 years

          -  no history of chronic diseases

          -  no taken medications

        Exclusion Criteria:

          -  do not prescribe their diet

          -  mental retardation
      

Gender

All

Ages

6 Years - 11 Years

Accepts Healthy Volunteers

Accepts Healthy Volunteers

Contacts

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Location Countries

Iran, Islamic Republic of

Location Countries

Iran, Islamic Republic of

Administrative Informations


NCT ID

NCT01886482

Organization ID

high protein diet in childhood


Responsible Party

Principal Investigator

Study Sponsor

Isfahan University of Medical Sciences


Study Sponsor

, , 


Verification Date

June 2013