Assessment of the V600E Mutation in the B-RAF Gene in Chronic Lymphoproliferative Disease

Brief Title

Assessment of the V600E Mutation in the B-RAF Gene in Chronic Lymphoproliferative Disease

Official Title

Assessment of the V600E Mutation in the B-RAF Gene in Chronic Lymphoproliferative Disease.

Brief Summary

      The presence of a specific mutation in the gene known as B-RAF has been found in patients who
      have Hairy Cell Leukemia. In this study this specific mutation known as V600E will be
      ascertained in peripheral blood samples of patients who have this disease and in a group of
      patients who have a similar chronic lymphoproliferative conditions such as splenic marginal
      lymphoma. The finding of this specific mutation will help to verify or exclude the diagnosis
      of Hairy Cell Leukemia and determine whether patients are in remission.
    



Study Type

Observational


Primary Outcome

detection of the B-RAF V600E mutation


Condition

Hairy Cell Leukemia



Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information



Estimated Enrollment

20

Start Date

November 2012

Completion Date

April 2013

Primary Completion Date

March 2013

Eligibility Criteria

        Inclusion Criteria:

        Patients over the age of 18 years -

        Exclusion Criteria:

        Patients less than 18 years in age or mentally defectives.

        -
      

Gender

All

Ages

18 Years - N/A

Accepts Healthy Volunteers

No

Contacts

, , 



Administrative Informations


NCT ID

NCT01720758

Organization ID

EMC-0124-11-CTIL


Responsible Party

Sponsor

Study Sponsor

HaEmek Medical Center, Israel


Study Sponsor

, , 


Verification Date

August 2017