Application of Virtual Mandibular Position in Temporomandibular Jont Reconstruction With Costochondral Graft in Children Jaw Deformity

Brief Title

Application of Virtual Mandibular Position in Temporomandibular Jont Reconstruction With Costochondral Graft in Children Jaw Deformity

Official Title

Application of Virtual Mandibular Position in Temporomandibular Jont Reconstruction With Costochondral Graft in Children Jaw Deformity.

Brief Summary

      Hypothesis:Computer-aided design virtual mandibular position is feasible for costochondral
      graft growing and occlusion stabilizing in the one-stage treatment of children
      temporomandibular joint ankylosis (TMJA) or condyle absence with jaw deformity.

      Methods: The inclusion criteria is children patients younger than 12 years old with
      unilateral TMJA or condyle absence. A virtual mandibular position is designed preoperatively
      according to the CT data of jaw and dentition. 3D printed templates and occlusal splints are
      used to guide the costochondral graft and mandibular position. During surgery, the affected
      ramus is reconstructed with costochondral grafting under the virtual mandibular position.
      After surgery, the occlusal splint is fixed to maxilla at least one month, and then, replaced
      by orthodontic functional appliance to promote downward growth of the maxilla. Occlusion,
      facial symmetry, costochondral graft growing would be evaluated and analysed until adulthood.
    



Study Type

Observational [Patient Registry]


Primary Outcome

Bilateral ramus height,chin deviation,maxilla height


Condition

Temporomandibular Joint Ankylosis

Intervention

temporomandibular jont reconstruction with costochondral transplantation

Study Arms / Comparison Groups

 Children TMJA or condyle absence with Jaw Deformity
Description:  inclusion criteria: <12 years old; Unilateral temporomandibular joint ankylosis or condyle absence; Temporomandibular joint reconstructed with costochondral graft;

Publications

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information


Recruitment Status

Procedure

Estimated Enrollment

15

Start Date

September 1, 2018

Completion Date

September 1, 2021

Primary Completion Date

September 1, 2020

Eligibility Criteria

        Inclusion Criteria:

          -  <12 years old

          -  Unilateral temporomandibular joint ankylosis or condyle absence;

          -  Temporomandibular joint reconstructed with costochondral graft;

        Exclusion Criteria:

          -  Bilateral temporomandibular joint ankylosis or condyle absence

          -  Combined with systematic disease
      

Gender

All

Ages

6 Years - 12 Years

Accepts Healthy Volunteers

No

Contacts

Yi Zhang, PhD, +86 15910920699, [email protected]

Location Countries

China

Location Countries

China

Administrative Informations


NCT ID

NCT03845088

Organization ID

schen


Responsible Party

Principal Investigator

Study Sponsor

Peking University


Study Sponsor

Yi Zhang, PhD, Study Chair, Peking University Hospital of Stomatology


Verification Date

May 2020