Treatments

The following database contains products that have been granted orphan status, or have been market approval in the EU or the USA.

You can filter the content by clicking on the titles: Product, Indication, Sponsor and Date. Clicking once, will filter the column alphabetically from A – Z and a second click on the same title will filter from Z – A.

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Country Product Indication Sponsor Date
Antagonist of the complement 5a receptor Microscopic polyangiitis ChemoCentryx, Inc.;850 Maude Avenue;Mountain View, California, 94043 June 2, 2014
Humanized IgG monoclonal antibody hRS7 conjugated to topoisomerase I inhibitor Pancreatic cancer Immunomedics, Inc.;300 The American Road;Morris Plains, NJ, 07950 May 29, 2014
Human Monoclonal Antibody against Epidermal Growth Factor Receptor Linked to Monomethylauristatin F Glioblastoma AbbVie, Inc.;1 N. Waukegan Road;North Chicago, Illinois, 60064 May 29, 2014
Sacituzumab govitecan Pancreatic cancer Immunomedics, Inc.;300 The American Road;Morris Plains, New Jersey, 07950 May 29, 2014
All-cis-docosa-4,7,10,13,16,19-hexaenoic acid Retinitis pigmentosa Natac Pharma, S.L.;C/ Faraday 7, 28049;Madrid May 21, 2014
4-{[(2R,3S,4R,5S)-4-(4-Chloro-2-fluoro-phenyl)-3-(3-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2-dimethyl-propyl)-pyrrolidine-2-carbonyl]-amino}-3-methoxy-benzoic acid Acute myeloid leukemia Roche Genentech;F. Hoffmann-La Roche Ltd., 430 East 29th Street;New York, New York, 10016 May 19, 2014
Inecalcitol Chronic lymphocytic leukemia Hybrigenics, S.A.;3-5 Impasse Reille, 75014;Paris May 14, 2014
177Lu-tetraxetan-tetulomab Follicular lymphoma Nordic Nanovector AS;Anniken Hagen, Kjelsasveien 168B, NO-0884;Oslo May 14, 2014
[a-N-(2’succinyl-paclitaxel)Thr]-Phe-Phe-Tyr-Gly-Gly-Ser-Arg-Gly-[epsilon-N-(2’succinyl-paclitaxel)Lys]-Arg-Asn-Asn-Phe-[epsilon-N-(2’succinyl-paclitaxel)Lys]-Thr-Glu-Glu-Tyr Glioblastoma Angiochem, Inc.;201 President-Kennedy Avenue, MOntreal QCH2X 3Y7; May 14, 2014
Menadione Sodium Bisulfite Polycystic kidney disease- type 1 IC-MedTech Corporation;9902 Indian Creek Lane;El Cajon, California, 92021 May 14, 2014
Afamelanotide Familial benign chronic pemphigus (Hailey-Hailey disease) Clinuvel, Inc.;40 Worth Street, 10th Floor - Suite 1053;New York, New York, 10013 May 14, 2014
(Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N-(pyrazin-2-yl)acrylohydrazide Diffuse Large B-cell Lymphoma Karyopharm Therapeutics, Inc.;2 Mercer Road;Natick, Massachusetts, 01760 May 14, 2014
Targeted Gastrin 17 Complexed Peptide Pancreatic Cancer Tyg Oncology Ltd;Synergy House, 7 Acorn Business Park, Nottinghamshire NG18 1 EX; May 14, 2014
Selinexor; (Z)-3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N-(pyrazin-2-yl)acrylohydrazide Acute myeloid leukemia Karyopharm Therapeutics, Inc.;2 Mercer Road;Natick, Massachusetts, 01760 May 14, 2014
Diazoxide choline Prader-Willi syndrome Soleno Therapeutics, Inc.;1235 Radio Road, Suite 110;Redwood City, California, 94065 May 13, 2014
Adalimumab Non-infectious intermediate, posterior, or pan-uveitis, or chronic non-infectious anterior uveitis AbbVie, Inc.;1 North Waukegan Road;North Chicago, Illinois, 60064 May 13, 2014
Ex vivo cultured human mesenchymal stromal cells Prevention of graft rejection following solid organ transplantation iCell Science AB;Tallmov. 2A, 756 45 Uppsala; May 8, 2014
Autologous dendritic cells pulsed with allogeneic tumor cell lysate Malignant pleural mesothelioma Amphera BV;Onderwijs Blvd 219, 5223 DE's-Hertogenbosch; May 6, 2014
Filanesib Multiple myeloma Array BioPharma, Inc.;3200 Walnut Street;Boulder, Colorado, 80301 May 6, 2014
(3E,5E)-3,5-bis[(4-fluoro-3-nitrophenyl)methylidene]-1-(prop-2-enoyl)azepan-4-0ne Multiple myeloma VivoLux AB;Uppsala Science Park, SE-751 83 Uppsala; April 30, 2014
Demcizumab Pancreatic Cancer OncoMed Pharmaceuticals, Inc.;800 Chesapeake Drive;Redwood City, California, 94063 April 30, 2014
Ipatasertib Stomach Cancer Genentech, Inc.;1 DNA Way;South San Francisco, California, 94080 April 30, 2014
Recombinant AAV9 expressing human alpha-N-acetylglucosaminidase Mucopolysaccharidosis III-B (Sanfilippo Syndrome Type B) Abeona Therapeutics LLC;10000 Cedar Avenue;Cleveland, Ohio, 44106 April 30, 2014
18-(p-[124I]-iodophenyl)octadecyl phosphocholine Glioma Cellectar Biosciences, Inc.;3301 Agriculture Drive;Madison, Wisconsin, 53716 April 30, 2014
Human plasma derived conagulation protein-Factor XI For the treatment of congenital Factor XI deficiency Cambryn Biologics;600Tallevast Rd, Unit 201;Sarasota, Florida, 34243 April 30, 2014