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Treatments
The following database contains products that have been granted orphan status, or have been market approval in the EU or the USA.
You can filter the content by clicking on the titles: Product, Indication, Sponsor and Date. Clicking once, will filter the column alphabetically from A – Z and a second click on the same title will filter from Z – A.
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Country | Product | Indication | Sponsor | Date |
---|---|---|---|---|
N-(2-{2-dimethylaminoethyl-methylamino}-4-methoxy-5-{[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide mesylate salt | Epidermal growth factor receptor mutation-positive non-small cell lung cancer | AstraZeneca Pharmaceuticals LP;P. O. Box 8355, 1800 Concord Pike;Wilmington, DE, 19803-8355 | September 4, 2014 | |
6-((3S,4S)-4-Methyl-1-pyrimidin-2-ylmethyl-pyrrolidin-3-yl-1-(tetrahydro-pyran-4-yl)-1,5-dihydro-pryazolo[3,4-d]pyrimidin-4-one | Sickle cell anemia | Pfizer, Inc.;500 Arcola Road;Collegeville, Pennsylvania, 19426 | September 4, 2014 | |
Methotrexate | Myasthenia gravis Myasthenia gravis | The Universtiy of Kanasa Medical Center;3901 Rainbow Blvd, MSN 2012;Kanasa City, Kansas, 66160 | August 28, 2014 | |
2-{[(1r,4r)-4-(((4-chlorophenyl)(phenyl)carbamoyloxy)methyl)cyclohexy]methoxy} acetic acid | Pulmonary Arterial Hypertension | Arena Pharmaceuticals, Inc.;6154 Nancy Ridge Drive;San Diego, California, 92121 | August 28, 2014 | |
Spanlecortemlocel | Acute lymphoblastic leukemia | Novartis Pharmaceuticals Corporation;One Health Plaza;East Hanover, New Jersey, 07936 | August 27, 2014 | |
Gefitinib | Non-small cell lung cancer | AstraZeneca Pharmaceuticals LP;1800 Concord Pike, P. O. Box 8355;Wilmington, Delaware, 19803 | August 26, 2014 | |
(3S)-1-azabicylo[2.2.2]oct-3yl {2-[2-(4-fluorophenyl)-1,3-thiazol-4-yl]propan-2-yl}carbamate | Fabry disease | Genzyme Corporation;500 Kendall Street;Cambridge, Massachusetts, 01242 | August 26, 2014 | |
Venglustat | Fabry disease | Genzyme Corporation;500 Kendall Street;Cambridge, Massachusetts, 01242 | August 26, 2014 | |
Cannabidiol | Glioblastoma | Insys Development Company, Inc.;1333 S. Spectrum Blvd, Suite 100;Chandler, Arizona, 85286 | August 20, 2014 | |
Lacnotuzumab | Pigmented villonodular synovitis, including giant cell tumor of the tendon sheath | Novartis Pharmaceuticals Corp;One Health Plaza;East Hanover, New Jersey, 07936 | August 19, 2014 | |
Dexrazoxane hydrochloride | Prevention of cardiomyopathy for chilren and adolescents 0 through 16 years of age treated with anthracyclines | Satiscor, LLC;45 Marine Road;Boston, Massachusetts, 02127 | August 19, 2014 | |
Altiratinib | Glioblastoma | Deciphera Pharmaceuticals, LLC;643 Massachusetts, Suite 200;Lawrence, Kansas, 66044 | August 19, 2014 | |
Immune Globulin Subcutaneous (Human), 20% Liquid | Chronic inflammatory demyelinating polyneuropathy | CSL Behring;P. O. Box 61501, 1020 First Avenue;King of Prussia, Pennsylvania, 19406 | August 18, 2014 | |
Dry extract from Betulae Cortex (birch bark) | Dystrophic epidermolysis bullosa | Birken AG;Streiflingsweg 11;Niefern-Oeschelbronn | August 7, 2014 | |
N1,N14,-diethyl-3,12,-dihydroxyhomospermine | Pancreatic Cancer | Sun BioPharma, Inc.;712 Vista Blvd, Suite 305;Waconia, Minnesota, 55387 | August 7, 2014 | |
Anti-Beta1 integrin monoclonal antibody | Glioblastoma | OncoSynergy, Inc.;409 Illinois Street, Room 3044;San Francisco, California, 94158 | August 7, 2014 | |
Roseburia hominis | Ulcerative colitis | 4D Pharma Research Ltd;Life Sciences Innovation Bldg, Cornhill Road; | August 4, 2014 | |
Binimetinib | Ovarian cancer | Array Biopharma, Inc.;3200 Walnut Street;Boulder, Colorado, 80301 | July 31, 2014 | |
Antibody drug conjugate consisting of a humanized IgG1 anti-NaPi2b monoclonal antibody and monomethyl auristatin E | Ovarian cancer | Genentech, Inc.;1 DNA Way;South San Francisco, California, 94080 | July 29, 2014 | |
Antibody drug conjugate consisting of fully human anti-guanylyl cyclase C monoclonal antibody linked to the cytotoxic drug monomethyl auristatin E | Stomach Cancer | Millennium Pharmaceuticals, Inc.;40 Landsdowne Street;Cambridge, Massachusetts, 02139 | July 21, 2014 | |
2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thienol[3,2,-f]-[1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]-N-(4-hydroxyphenyl)-acetamide dihydrate | Acute myeloid leukemia | OncoEthix GmbH (Merck Subsidiary);Weystrasse 20, 6000 Lucerne; | July 16, 2014 | |
Paclitaxel-coated buttress | For use as local administration at the time of curative surgery in the treatment of stage 0 to III non-small cell lung cancer | AcuityBio, Inc.;200 Upland Road;Newton, Massachusetts, 02460 | July 15, 2014 | |
Adalimumab | Behçet’s Disease | Mucora;32b Eisenberg St, Rehovot 7628810; | July 10, 2014 | |
Adeno-associated viral vector serotype 2 containing the humanREP1gene | Choroideremia | NightstaRx Ltd. | July 4, 2014 | |
Bendamustine for 50 ml admixture | Chronic lymphocytic leukemia | Eagle Pharmaceuticals, INc.;50 Tice Blvd, Suite 315;Woodcliff Lake, New Jersey, 07677 | July 2, 2014 |