VLA-4 and LFA-1 integrin activator January 19, 2018 VLA-4 and LFA-1 integrin activator Trade Name Orphan Indication Malignant melanoma stages IIB to IV USA Market Approval USA USA Designation Date 2017-11-08 00:00:00 Sponsor 7 Hills Pharma, LLC;8285 El Rio Street, Suite 130;Houston, Texas, 77054