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Treatments
The following database contains products that have been granted orphan status, or have been market approval in the EU or the USA.
You can filter the content by clicking on the titles: Product, Indication, Sponsor and Date. Clicking once, will filter the column alphabetically from A – Z and a second click on the same title will filter from Z – A.
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| Country | Product | Indication | Sponsor | Date |
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Itraconazole | Nevoid basal cell carcinoma syndrome | HedgePath Pharmaceuticals, Inc;324 South Hyde Park Avenue, Suite 350;Tampa, Florida, 33606 | May 19, 2016 |
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Ropidoxuridine (5-iodo-2-pyrimidinone-2′-deoxyribose) | Glioblastoma | EMEK, Inc.;196 Channel View;Warwick, Rhode Island, 02889 | May 19, 2016 |
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Tetrandrine | Chronic myeloid leukemia | Escend Pharmaceuticals, Inc.;3475 Edison Way, Suite R;Menlo Park, California, 94025 | May 19, 2016 |
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(2,2-diphenyl-tetrahydro-furan-3-yl-methyl)-dimethylamine hydrochloride | Rett like syndrome | Anavex Life Sciences Corporation;51 West 52nd Street, 7th Floor;New York, New York, 10019 | May 18, 2016 |
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Anti-HER2 bispecific antibody | Ovarian cancer | Zymeworks Inc.;18 West Mercer Street, Suite 370;Seattle, Washington, 98119 | May 18, 2016 |
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Human monoclonal antibody directed against tissue factor pathway inhibitor | Hemophilia A | Pfizer, Inc.;500 Arcola Road;Collegeville, Pennsylvania, 19426 | May 18, 2016 |
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Ustekinumab | pediatric Crohn’s disease | Janssen Research & Development, LLC;P. O. Box 776, 1400 McKean Road;Spring House, Pennsylvania, 19477 | May 18, 2016 |
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Combination of disulfiram and copper gluconate | Glioblastoma | Cantex Pharmaceuticals, Inc.;1792 Bell Tower Lane;Weston, Florida, 33326 | May 18, 2016 |
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Liposomal glutathione | Dengue Virus infection | Your Energy Systems, LLC;555 Bryant Street #305;Palo Alto, California, 94301 | May 18, 2016 |
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2-amino-N-({methyl-[(6-trifluoromethoxy-benzothiazol-2-ylcarbamoyl)-methyl]-carbamoyl}-methyl)-acetamide monohydrochloride | Spinocerebellar ataxia | Biohaven Pharmaceuticals, Inc.;234 Church Street, Suite 304;New Haven, Connecticut, 06510 | May 18, 2016 |
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Copper 64-DOTA-TATE | Diagnostic for the management of neuroendocrine tumors | RadioMedix, Inc.;9701 Richmond Avenue, Suite 222;Houston, Texas, 77042 | May 18, 2016 |
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Taurolidine | Pancreatic cancer | Geistlich Pharma NA, Inc.;202 Carnegie Center Drive;Princeton, New Jersey, 08540 | May 16, 2016 |
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(R)-1-[1-(4-Acetoxy-3,3-dimethyl-2-oxo-butyl)-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-3-(3-methylamino-phenyl)-urea | Gastric neuroendocrine tumors (gastric NETs) | Trio Medicines Ltd.;Pavillion View, Brighton BN1 1EY; | May 12, 2016 |
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Naratuximab emtansine | Diffuse Large B-cell Lymphoma | Debiopharm International S.A.;Forum "apres-demain", Chemin Messidor 5-7, CP 5911; | May 12, 2016 |
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Maytansinoid-conjugated humanized monoclonal antibody against CD37 | Diffuse Large B-cell Lymphoma | Debiopharm International S.A.;Forum "apres-demain", Chemin Messidor 5-7, CP 5911; | May 12, 2016 |
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Florilglutamic acid | Glioma | Piramal Imaging S.A.;13 Route de l'Ecole;Matran | May 11, 2016 |
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Autologous T-lymphocytes transduced with anti-BCMA02 CAR lentiviral vector encoding a chimeric antigen receptor (CAR) specific for the human B cell maturation antigen | Multiple myeloma | Celgene Corporation;86 Morris Avenue;Summit, New Jersey, 07901 | May 11, 2016 |
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6-methoxy-3-(3′,4′,5′-trimethoxybenzoyl) indole | Bile duct cancer | SynCore Biotechnology Co. Ltd.;4F, 69 Dongxing Road, XinYi Dist; | May 11, 2016 |
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Autologous ex vivo expanded polyclonal CD4+CD25+CD1271o/-FOXP3+ Regulatory T cells | Type 1 diabetes mellitus with residual beta cell function | Caladrius Biosciences;110 Allen Road, 2nd Floor;Basking Ridge, New Jersey, 07920 | May 10, 2016 |
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Selumetinib | Adjuvant treatment of patients with stage III or stage IV differentiated thyroid cancer | AstraZeneca Pharmaceuticals LP;1800 Concord Pike, P. O. Box 8355;Wilmington, Delaware, 19803 | May 10, 2016 |
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Enfumafungin derivative B-(1,3)-D-glucan synthestis inhibitor | Invasive Candida infections, including candidemia | SCYNEXIS, Inc.;101 Hudson Street, Suite 3610;Jersey City, New Jersey, 07302 | May 10, 2016 |
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Recombinant protein inhibitor of complement factor 5 | Guillain-Barré syndrome | Akari Therapeutics Plc;24 West 40th Street, 8th Floor;New York, New York, 10018 | May 10, 2016 |
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2′-O-(2-methoxyethyl)phosphorothioate antisense oligonucleotide | Acromegaly | Antisense Therapeutics Limited;6 Wallace Avenue, TOORAK VIC 3142;Trevose | May 10, 2016 |
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Clotrimazole otic solution | Fungal otitis externa (otomycosis) | Laboratorios SALVAT S.A.;C/ Gall, 30-36, Esplugues de Llobregat;Barcelona | May 10, 2016 |
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Human recombinant bone morphogenetic protein 4 | Glioblastoma | HyperStem Therapeutics, Inc.;13223-1 Black Mountain Road;San Diego, California, 92129 | May 4, 2016 |