Disease: Tuberous sclerosis- type 2
- <em>Tsc2</em> shapes olfactory bulb granule cell molecular and morphological characteristics
- A new view of macula densa cell protein synthesis
- A novel role of CRTC2 in promoting nonalcoholic fatty liver disease
- A single-center observational study on long-term neurodevelopmental outcomes in children with tuberous sclerosis complex
- Aberrant DJ-1 expression underlies L-type calcium channel hypoactivity in dendrites in tuberous sclerosis complex and Alzheimer's disease
- Amplification of human interneuron progenitors promotes brain tumors and neurological defects
- An overview of actionable and potentially actionable TSC1 and TSC2 germline variants in an online Database
- Analysis of Clinical Features and Next-Generation Sequencing of 12 Tuberous Sclerosis Families in China
- Angiotensin II receptor type 1 blockade regulates Klotho expression to induce TSC2-deficient cell death
- Aspirin-exacerbated respiratory disease is associated with variants in filaggrin, epithelial integrity, and cellular interactions
- Autosomal dominant genodermatoses in adults being heralded by superimposed skin lesions in children
- Biallelic ELOC-Inactivated Renal Cell Carcinoma: Molecular Features Supporting Classification as a Distinct Entity
- Birth Characteristics Among Children Diagnosed with Neurofibromatosis Type 1 and Tuberous Sclerosis
- Cancer Predisposition Syndromes in Neuro-oncology
- Case report: The origin of transmantle-like features
- Cerebellar demyelination and neurodegeneration associated with mTORC1 hyperactivity may contribute to the developmental onset of autism-like neurobehavioral phenotype in a rat model
- Clinical characteristics and genetic analysis of a Chinese pedigree affected with tuberous sclerosis complex
- Construction of TSC2 knockout cell line using CRISPR/Cas9 system and demonstration of its effects on NIH-3T3 cells
- Cortical wiring by synapse type-specific control of local protein synthesis
- Cross talk between LAM cells and fibroblasts may influence alveolar epithelial cell behavior in lymphangioleiomyomatosis
- Cutaneous Angiofibroma
- Cutaneous Angiofibroma
- Dermoscopy of hypopigmented macules unveiling genetic diagnosis of tuberous sclerosis complex type 2 in an infant presenting with sacral chordoma
- Developmental effects of constitutive mTORC1 hyperactivity and environmental enrichment on structural synaptic plasticity and behaviour in a rat model of autism spectrum disorder
- Downregulated formyl peptide receptor 2 expression in the epileptogenic foci of patients with focal cortical dysplasia type IIb and tuberous sclerosis complex
- Early diagnosis of a newborn with tuberous sclerosis caused by a genetic mutation
- Early Post-Natal Immune Activation Leads to Object Memory Deficits in Female <em>Tsc2</em><sup>+/-</sup> Mice: The Importance of Including Both Sexes in Neuroscience Research
- Ectopic HCN4 Provides a Target Biomarker for the Genetic Spectrum of mTORopathies
- Effects of Mutations in TSC Genes on Neurodevelopment and Synaptic Transmission
- Eosinophilic, solid, and cystic renal cell carcinoma (ESC-RCC)
- Epilepsy severity mediates association between mutation type and ADHD symptoms in tuberous sclerosis complex
- Epilepsy surgery in children with tuberous sclerosis
- Epilepsy Surgery in Young Children With Tuberous Sclerosis Complex: A Novel Hybrid Multimodal Surgical Approach
- Epileptic spasms are associated with increased stereo-electroencephalography derived functional connectivity in tuberous sclerosis complex
- Estradiol ameliorates metformin-inhibited Sertoli cell proliferation via AMPK/TSC2/mTOR signaling pathway
- Familial Neoplastic Syndromes
- Genetics of Pancreatic Neuroendocrine Tumors
- Identification of an Electrogenic 2Cl(-)/H(+) Exchanger, ClC5, as a Chloride-Secreting Transporter Candidate in Kidney Cyst Epithelium in Tuberous Sclerosis
- Identification of an Electrogenic 2Cl<sup>-</sup>/H<sup>+</sup> Exchanger, ClC5, as a Chloride-Secreting Transporter Candidate in Kidney Cyst Epithelium in Tuberous Sclerosis
- Identification of serum and glucocorticoid-regulated kinase 1 as a regulator of signal transducer and activator of transcription 3 signaling
- Increased expression of complement components in tuberous sclerosis complex and focal cortical dysplasia type 2B brain lesions
- Interictal and seizure-onset EEG patterns in malformations of cortical development: A systematic review
- Interleukin-6 mediates PSAT1 expression and serine metabolism in TSC2-deficient cells
- Jagged-1 is induced by mTOR inhibitors in renal cancer cells through an Akt/ALK5/Smad4-dependent mechanism
- Kidney collecting duct cell type composition is regulated by Notch signaling via modulation of mTORC1
- LncRNA PVT-1 promotes osteosarcoma cancer stem-like properties through direct interaction with TRIM28 and TSC2 ubiquitination
- Long-term dietary DHA intervention prevents telomere attrition and lipid disturbance in telomerase-deficient male mice
- Loss of <em>TSC1/TSC2</em> sensitizes immune checkpoint blockade in non-small cell lung cancer
- Low-frequency electroacupuncture improves disordered hepatic energy metabolism in insulin-resistant Zucker diabetic fatty rats via the AMPK/mTORC1/p70S6K signaling pathway
- Low-grade oncocytic tumour of the kidney is characterised by genetic alterations of TSC1, TSC2, MTOR or PIK3CA and consistent GATA3 positivity
- Managing Headache Disorders Associated with Tuberous Sclerosis and Neurofibromatosis
- Mechanistic Target of Rapamycin Complex 1 Signaling Links Hypoxia to Increased IGFBP-1 Phosphorylation in Primary Human Decidualized Endometrial Stromal Cells
- Modeling tuberous sclerosis complex with human induced pluripotent stem cells
- MR Imaging Detection of CNS Lesions in Tuberous Sclerosis Complex: The Usefulness of T1WI with Chemical Shift Selective Images
- mTOR Pathway Somatic Pathogenic Variants in Focal Malformations of Cortical Development: Novel Variants, Topographic Mapping, and Clinical Outcomes
- Multidisciplinary neurocutaneous syndrome clinics: a systematic review and institutional experience
- Multidisciplinary Outpatient Clinic of Neurocutaneous Diseases: Five-year Experience of a Pediatric Tertiary Hospital in Portugal
- Multifocality is not associated with worse survival in sporadic pancreatic neuroendocrine tumors
- Nervous system (NS) Tumors in Cancer Predisposition Syndromes
- Neurocutaneous Disorders in Pregnancy
- Neurocutaneous Syndromes, Perinatal Factors, and the Risk of Childhood Cancer in Sweden
- Neurodevelopmental Findings and Epilepsy in Malformations of Cortical Development
- Neuroendocrine neoplasms in the context of inherited tumor syndromes: a reappraisal focused on targeted therapies
- Neurofibromatosis Type 1
- Neurofibromatosis Type 1
- Neurofibromatosis type1, type 2, tuberous sclerosis and Von Hippel-Lindau disease
- Orbital Perivascular Epithelioid Cell Tumor in a Case of Tuberous Sclerosis
- Overview of therapeutic options for epilepsy
- Pancreatic neuroendocrine neoplasms: Updates on genomic changes in inherited tumour syndromes and sporadic tumours based on WHO classification
- Pediatric cervical kyphosis in the MRI era (1984-2008) with long-term follow up: literature review
- Perinatal adversities in tuberous sclerosis complex: Determinants and neurodevelopmental outcomes
- Periplaneta americana extract CⅡ-3 induces senescence of leukemia K562 cells via SIRT1/mTOR signaling pathway
- Perivascular Epithelioid Cell-Family Tumors in Children, Adolescents and Young Adults:Clinicopathologic Features in 70 Cases
- Persistent mTORC1 activation due to loss of liver tuberous sclerosis complex 1 promotes liver injury in alcoholic hepatitis
- Phosphorylation of PBX2, a novel downstream target of mTORC1, is determined by GSK3 and PP1
- Prdx5 in the Regulation of Tuberous Sclerosis Complex Mutation-Induced Signaling Mechanisms
- Presynaptic GABA<sub>B</sub> receptor-mediated network excitation in the medial prefrontal cortex of Tsc2<sup>+/-</sup> mice
- Prophylactic Steroids for Preventing Postembolization Syndrome after Transcatheter Arterial Embolization of Renal Angiomyolipoma: A Comparative Study
- Refractive Errors, Retinal Findings, and Genotype of Tuberous Sclerosis Complex: A Retrospective Cohort Study
- Role of Type I Interferon Signaling and Microglia in the Abnormal Long-term Potentiation and Object Place Recognition Deficits of Male Mice With a Mutation of the Tuberous Sclerosis 2 Gene
- Second-line cannabis therapy in patients with epilepsy
- Solitary atrial Rhabdomyoma in an infant with tuberous sclerosis: a case report and review of the literature
- Somatic mutations involving TSC 1 and TSC2 genes in two children with focal cortical dysplasia
- Syndroms associated with benign skin tumors
- Targeting autophagy using small-molecule compounds to improve potential therapy of Parkinson's disease
- Taylor's focal cortical dysplasia revisited: History, original specimens and impact
- The risk of glaucoma associated with phacomatosis cesioflammea and phacomatosis cesioflammeo-marmorata
- The therapeutic potential of purified cannabidiol
- Transition readiness in adolescents and young adults with chronic genetic skin conditions
- TSC1/2 mutations-a unique type of mutation suitable for liver transplantation of Hepatocellular carcinoma
- Tsc2 mutation rather than Tsc1 mutation dominantly causes a social deficit in a mouse model of tuberous sclerosis complex
- TSC2 regulates tumor susceptibility to TRAIL-mediated T-cell killing by orchestrating mTOR signaling
- Tuberous Sclerosis Complex (TSC) Inactivation Increases Neuronal Network Activity by Enhancing Ca(2+) Influx via L-Type Ca(2+) Channels
- Tuberous Sclerosis Complex (TSC) Inactivation Increases Neuronal Network Activity by Enhancing Ca<sup>2+</sup> Influx via L-Type Ca<sup>2+</sup> Channels
- Tuberous Sclerosis, Type II Diabetes Mellitus and the PI3K/AKT/mTOR Signaling Pathways-Case Report and Literature Review
- Tumor Syndromes: Neurosurgical Evaluation and Management
- Tyrosine Kinase Inhibitors Diminish Renal Neoplasms in a Tuberous Sclerosis Model Via Induction of Apoptosis
- Vascular endothelial growth factor-C modulates cortical NMDA receptor activity in cortical lesions of young patients and rat model with focal cortical dysplasia
- Whole Exome Sequencing in a Series of Patients with a Clinical Diagnosis of Tuberous Sclerosis Not Confirmed by Targeted <em>TSC1/TSC2</em> Sequencing
- Whole Exome Sequencing in a Series of Patients with a Clinical Diagnosis of Tuberous Sclerosis Not Confirmed by Targeted TSC1/TSC2 Sequencing