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• Cockayne Syndrome Linked to Elevated R-Loops Induced by Stalled RNA Polymerase II during Transcription Elongation
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• Considerations for fatty acids in standardized reference diet for parthenogenetic marbled crayfish Procambarus virginalis model organism
• Contemporary Perspectives on the Role of Vitamin D in Enhancing Gut Health and Its Implications for Preventing and Managing Intestinal Diseases
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• FAM122A ensures cell cycle interphase progression and checkpoint control by inhibiting B55α/PP2A through helical motifs
• Gallic Acid Enhances the Efficacy of BCR::ABL1 Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia through Inhibition of Mitochondrial Respiration and Modulation of Oncogenic Signaling Pathways
• GBF1 deficiency causes cataracts in human and mouse
• Ginsenoside RK1 Induces Ferroptosis in Hepatocellular Carcinoma Cells through an FSP1-Dependent Pathway
• Glucose-6-phosphate dehydrogenase maintains redox homeostasis and biosynthesis in LKB1-deficient KRAS-driven lung cancer
• GPR50 regulates neuronal development as a mitophagy receptor
• Harnessing DNA replication stress to target RBM10 deficiency in lung adenocarcinoma
• Hedgehog pathway and cancer: A new area (Review)
• High-sensitive sensory neurons exacerbate rosacea-like dermatitis in mice by activating γδ T cells directly
• Humoral immune responses primed by the alteration of gut microbiota were associated with galactose-deficient IgA1 production in IgA nephropathy
• Identification of Biomarkers for Lung Adenocarcinoma With Qi Deficiency and Phlegm Dampness
• Identification of novel small molecule-based strategies of COL7A1 upregulation and readthrough activity for the treatment of recessive dystrophic epidermolysis bullosa
• Integration of QTL and comprehensive analysis in the circulating inflammatory cytokines for pan-cancer
• International Society on Thrombosis and Haemostasis clinical practice guideline for treatment of congenital hemophilia A and B based on the Grading of Recommendations Assessment, Development, and Evaluation methodology
• Iron-dependent KDM4D activity controls the quiescence-activity balance of MSCs via the PI3K-Akt-Foxo1 pathway
• KARS Mutations Impair Brain Myelination by Inducing Oligodendrocyte Deficiency: One Potential Mechanism and Improvement by Melatonin
• Lactate contributes to remote ischemic preconditioning-mediated protection against myocardial ischemia reperfusion injury by facilitating autophagy via AMPK-mTOR-TFEB-CX43 axis
• Lactate Contributes to Remote Ischemic Preconditioning-Mediated Protection Against Myocardial Ischemia Reperfusion Injury by Facilitating Autophagy via the AMPK-Mammalian Target of Rapamycin-Transcription Factor EB-Connexin 43 Axis
• LAG-3 and PD-1 synergize on CD8⁺ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity
• LncRNAH19 acts as a ceRNA of let-7 g to facilitate endothelial-to-mesenchymal transition in hypoxic pulmonary hypertension via regulating TGF-β signalling pathway
• Loss of tolerance precedes triggering and lifelong persistence of pathogenic type I interferon autoantibodies
• m³C32 tRNA modification controls serine codon-biased mRNA translation, cell cycle, and DNA-damage response
• MAPK Signaling-Mediated RFNG Phosphorylation and Nuclear Translocation Restrain Oxaliplatin-Induced Apoptosis and Ferroptosis
• MARCH1 negatively regulates TBK1-mTOR signaling pathway by ubiquitinating TBK1
• MASP-2 deficiency does not prevent the progression of diabetic kidney disease in a mouse model of type 1 diabetes
• Mass spectrometry imaging of SOD1 protein-metal complexes in SOD1G93A transgenic mice implicates demetalation with pathology
• Msh3 and Pms1 Set Neuronal CAG-repeat Migration Rate to Drive Selective Striatal and Cortical Pathogenesis in HD Mice
• N6-methyladenosine demethylase ALKBH5 homologous protein protects against cerebral I/R injury though suppressing SNHG3-mediated neural PANoptosis: Involvement of m6A-related macromolecules in the diseases of nervous system
• Negative features of sporadic amyotrophic lateral sclerosis: Motor neurons of Onuf's nucleus survive in ADAR2-conditional knockout mice
• New findings about neuropathological outcomes in the PKU mouse throughout lifespan
• NF1-dependent disruption of the blood-nerve-barrier is improved by blockade of P2RY14
• Non-ceruloplasmin copper and urinary copper in clinically stable Wilson disease: Alignment with recommended targets
• O-Sialoglycoprotein Endopeptidase Deficiency Impairs Proteostasis and Induces Autophagy in Human Embryonic Stem Cells
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• Pathogenic R(163)W Variant of the Copper Chaperone for Sod1 (Ccs) Functions as an Anti-chaperone
• Pathogenic variants in KMT2C result in a neurodevelopmental disorder distinct from Kleefstra and Kabuki syndromes
• Pharmacological and pre-clinical safety profile of rSIV.F/HN, a hybrid lentiviral vector for cystic fibrosis gene therapy
• PKR Mediates the Mitochondrial Unfolded Protein Response through Double-Stranded RNA Accumulation under Mitochondrial Stress
• Plasminogen missense variants and their involvement in cardiovascular and inflammatory disease
• R-loop functions in Brca1-associated mammary tumorigenesis
• R-loop resolution by ARIP4 helicase promotes androgen-mediated transcription induction
• R-loops and impaired autophagy trigger cGAS-dependent inflammation via micronuclei formation in Senataxin-deficient cells
• Recent Advances in Pre-Clinical Development of Adiponectin Receptor Agonist Therapies for Duchenne Muscular Dystrophy
• Relationship between adipokines and androgens in children and young adults with congenital adrenal hyperplasia
• Reticulated Retinoic Acid Synthesis is Implicated in the Pathogenesis of Dry Eye in Aqp5 Deficiency Mice
• Rhizobia cystathionine γ-lyase-derived H2S delays nodule senescence in soybean
• RYR2 deficient human model identifies calcium handling and metabolic dysfunction impacting pharmacological responses
• SARS-CoV-2 brainstem encephalitis in human inherited DBR1 deficiency
• SGK3 deficiency in macrophages suppresses angiotensin II-induced cardiac remodeling via regulating Ndufa13-mediated mitochondrial oxidative stress
• Shionone relieves oxygen-glucose deprivation/reoxygenation induced SH-SY5Y cells injury by inhibiting the p38 MAPK/NF-κB pathway
• SIGLEC15, negatively correlated with PD-L1 in HCC, could induce CD8+ T cell apoptosis to promote immune evasion
• SMARCA2 and SMARCA4 Participate in DNA Damage Repair
• Structural basis for a Polθ helicase small-molecule inhibitor revealed by cryo-EM
• Structural basis for the transport and regulation mechanism of the Multidrug resistance-associated protein 2
• Targeting myeloid-derived suppressor cells promotes antiparasitic T-cell immunity and enhances the efficacy of PD-1 blockade (15 words)
• The association between taurine concentrations and dog characteristics, clinical variables, and diet in English cocker spaniels: The Canine taURinE (CURE) project
• The contribution of commonly consumed edible insects to nutrition security in the Eastern D.R. Congo
• The expression and clinical significance of CFAP65 in colon cancer
• The P2 protein of wheat yellow mosaic virus acts as a viral suppressor of RNA silencing in Nicotiana benthamiana to facilitate virus infection
• The unfolded protein response sensor PERK mediates mechanical stress-induced maturation of focal adhesion complexes in glioblastoma cells
• Time-Restricted Feeding Reduces Atherosclerosis in LDLR KO Mice but Not in ApoE Knockout Mice
• Trackins (Trk-Targeting Drugs): A Novel Therapy for Different Diseases
• TRAP1 drives smooth muscle cell senescence and promotes atherosclerosis via HDAC3-primed histone H4 lysine 12 lactylation
• Unraveling the role of Major Vault Protein as a novel immune-related biomarker that promotes the proliferation and migration in pancreatic adenocarcinoma
• USP26 suppresses type I interferon signaling by targeting TRAF3 for deubiquitination