Research By Disease – CheckOrphan

Disease: Primary amoebic meningoencephalitis

Naegleria fowleri Detected in Grand Teton National Park Hot Springs
Naegleria fowleri: Understanding the Amoeba's Threat in Recreational Waters
A comparison of clinical outcomes associated with dosing metronidazole every 8 hours versus every 12 hours: a systematic review and metaanalysis
A giant virus infecting the amoeboflagellate Naegleria
A human pluripotent stem cell-derived in vitro model of the blood-brain barrier in cerebral malaria
Acetaminophen and Ibuprofen in Pediatric Central Nervous System Malaria: A Randomized Clinical Trial
An imported malaria case with repeated episodes of neurological syndromes resulting from different Plasmodium species
Apolipoprotein-E4: risk of severe malaria and mortality and cognitive impairment in pediatric cerebral malaria
Beyond the microcirculation: sequestration of infected red blood cells and reduced flow in large draining veins in experimental cerebral malaria
Biological screening for congenital toxoplasmosis in newborns from Jataí, Goiás, Brazil: a cross-sectional study
Blockage of mechanosensitive Piezo1 channel alleviates the severity of experimental malaria-associated acute lung injury
Bradykinin produced during Plasmodium falciparum erythrocytic cycle drives monocyte adhesion to human brain microvascular endothelial cells
Brain-eating amoeba: Recognition and treatment of primary amebic meningoencephalitis
Calcified cerebral toxoplasmosis associated with recurrent perilesional edema causing neurological manifestations in an HIV-infected individual: case report with a decade-long follow-up
Case Report: A Series of Three Meningoencephalitis Cases Caused by Acanthamoeba spp. from Eastern India
Cerebral malaria presenting as nonconvulsive status epilepticus: a case report
CEREBRAL TOXOPLASMOSIS IN THE COURSE OF HIV INFECTION - CASE STUDY
Cerebral toxoplasmosis mimicking stroke in a woman living with undiagnosed HIV
Combination of trimethoprim-sulfamethoxazole and clindamycin in the treatment of relapsing toxoplasmic encephalitis
Community and health worker perspectives on malaria in Meghalaya, India: covering the last mile of elimination by 2030
Comparative performance of ISAGA IgM and ELISA assays for the diagnosis of maternal and congenital Toxoplasma infections: which technique could replace ISAGA IgM?
Congenital Toxoplasmosis and Long-term Outcomes
Congenital toxoplasmosis of the brain caused by infection in late pregnancy
Corrigendum: Structural informatics approach for designing an epitope-based vaccine against the brain-eating Naegleria fowleri
Could PLATELIA Toxo IgM be the new gold standard for the serological diagnosis of congenital toxoplasmosis: a French multicenter study
Development and immunological evaluation of an mRNA-based vaccine targeting Naegleria fowleri for the treatment of primary amoebic meningoencephalitis
DON in pediatric cerebral malaria, a phase I/IIA dose-escalation safety study: study protocol for a clinical trial
Dynamic intravital imaging reveals reactive vessel-associated microglia play a protective role in cerebral malaria coagulopathy
Emergence of Naegleria fowleri as a fatal parasite in Pakistan
Emerging and Re-Emerging Parasitic Infections of the Central Nervous System (CNS) in Europe
Employing digital PCR for enhanced detection of perinatal Toxoplasma gondii infection: A cross-sectional surveillance and maternal-infant outcomes study in El Salvador
Enhanced anti-malarial efficacy of mefloquine delivered via cationic liposome in a murine model of experimental cerebral malaria
Enhanced Antimalarial and Antisequestration Activity of Methoxybenzenesulfonate-Modified Biopolymers and Nanoparticles for Tackling Severe Malaria
Enolase inhibitors as therapeutic leads for Naegleria fowleri infection
Evaluation of different cut-off points for IgG avidity and IgM in the diagnosis of acute toxoplasmosis in pregnant women participating in a congenital toxoplasmosis screening program
Exploring adjunctive therapies for cerebral malaria
Exploring therapeutic approaches against Naegleria fowleri infections through the COVID box
Extracellular vesicles derived from plasmodium-infected red blood cells alleviate cerebral malaria in plasmodium berghei ANKA-infected C57BL/6J mice
Fatal Case of Naegleria fowleri Primary Amebic Meningoencephalitis from Indoor Surfing Center, Taiwan, 2023
Feasibility, safety, and impact of the RTS,S/AS01E malaria vaccine when implemented through national immunisation programmes: evaluation of cluster-randomised introduction of the vaccine in Ghana, Kenya, and Malawi
Flucofuron as a Promising Therapeutic Agent against Brain-Eating Amoeba
Genetic characterization of Toxoplasma gondii from human and chicken isolates from Argentina
Hemichorea-hemiballismus associated with a case of cerebral toxoplasmosis in a hematopoietic stem cell transplant recipient
High-Throughput Screen of Microbial Metabolites Identifies F1FO ATP Synthase Inhibitors as New Leads for Naegleria fowleri Infection
Host Transcriptional Meta-signatures Reveal Diagnostic Biomarkers for Plasmodium falciparum Malaria
Immunofluorescence study of cytoskeleton in endothelial cells induced with malaria sera
In defense of children's brain: reshuffling the laboratory toolbox for the diagnosis of congenital toxoplasmosis
In silico discovery of diagnostic/vaccine candidate antigenic epitopes and a multi-epitope peptide vaccine (NaeVac) design for the brain-eating amoeba Naegleria fowleri causing human meningitis
In silico-based vaccine design against Naegleria fowleri causing primary amebic meningoencephalitis
Infected erythrocytes and plasma proteomics reveal a specific protein signature of severe malaria
Lactoferrin and Lysozyme Inhibit the Proteolytic Activity and Cytopathic Effect of Naegleria fowleri Enzymes
Long-term Ocular Outcomes in Congenital Toxoplasmosis Treated Perinatally
Longitudinal associations of plasma amino acid levels with recovery from malarial coma
Lymphatic network drainage resolves cerebral edema and facilitates recovery from experimental cerebral malaria
Malaria: A focused review for the emergency medicine clinician
Metagenomic next-generation sequencing for diagnosis of fatal Balamuthia amoebic encephalitis
Miconazole-like Scaffold is a Promising Lead for Naegleria fowleri-Specific CYP51 Inhibitors
Monocytes, particularly nonclassical ones, lose their opsonic and nonopsonic phagocytosis capacity during pediatric cerebral malaria
MRI-Based Brain Volume Scoring in Cerebral Malaria Is Externally Valid and Applicable to Lower-Resolution Images
Multicenter evaluation of the Toxoplasma gondii Real-TM (Sacace) kit performance for the molecular diagnosis of toxoplasmosis
Multiple Ring-Enhancing Brain Lesions: Fulminant Diffuse Cerebral Toxoplasmosis or Cerebral Metastases?
Murine model captures evolution of edema in experimental cerebral malaria
Naegleria fowleri in 2023: A rising threat to Pakistan
Nanoparticle-Terpene Fusion: A Game-Changer in Combating Primary Amoebic Meningoencephalitis Caused by Naegleria fowleri
Natural Terpenes Inhibit the Cytopathogenicity of Naegleria fowleri Causing Primary Amoebic Meningoencephalitis in the Human Cell Line Model
Natural Terpenes Inhibit the Cytopathogenicity of Naegleria fowleri Causing Primary Amoebic Meningoencephalitis in the Human Cell Line Model
Neurons upregulate PD-L1 via IFN/STAT1/IRF1 to alleviate damage by CD8+ T cells in cerebral malaria
Neuropilin-1 identifies a subset of highly activated CD8+ T cells during parasitic and viral infections
Next generation imidazothiazole and imidazooxazole derivatives as potential drugs against brain-eating amoebae
Noninvasive diagnostic biomarkers, genomic profiling, and advanced microscopic imaging in the early detection and characterization of Naegleria fowleri infections leading to primary amebic meningoencephalitis (PAM)
Novel paradigm enables accurate monthly gestational screening to prevent congenital toxoplasmosis and more
Observing astrocyte polarization in brains from mouse chronically infected with Toxoplasma gondii
Optimized Axenic Culture Medium for Comprehensive Biological and Physiological Analysis of Naegleria Fowleri
Oral administration of IPI549 protects mice from neuropathology and an overwhelming inflammatory response during experimental cerebral malaria
Post hospital admission blood lactate measurements are associated with mortality but not neurologic morbidity in children with cerebral malaria
Primary amebic meningoencephalitis: a review of Naegleria fowleri and analysis of successfully treated cases
Prokaryotic microbial ecology as an ecosurveillance tool for eukaryotic pathogen colonisation: Meiothermus and Naegleria fowleri
Prothrombotic autoantibodies targeting platelet factor 4/polyanion are associated with pediatric cerebral malaria
Providing an in vitro depiction of microglial cells challenged with immunostimulatory extracellular vesicles of Naegleria fowleri
Role of angiotensin pathway and its target therapy to rescue from experimental cerebral malaria
Role of astrocyte senescence regulated by the non- canonical autophagy in the neuroinflammation associated to cerebral malaria
Structural informatics approach for designing an epitope-based vaccine against the brain-eating Naegleria fowleri
Successful Treatment of Confirmed Naegleria fowleri Primary Amebic Meningoencephalitis
Sulfadiazine-induced crystalluria and non-oliguric renal failure in HIV-1 inaugural infection with presumed cerebral toxoplasmosis
Surveillance of Naegleria fowleri in Louisiana's public water systems
Synthesis and Biological Evaluation of Cyanoacrylamides and 5-Iminopyrrol-2-Ones Against Naegleria fowleri
Synthesis and Evaluation of Benzylamine Inhibitors of Neuropathogenic Naegleria fowleri "Brain-Eating" Amoeba
Synthetic angiotensin II peptide derivatives confer protection against cerebral and severe non-cerebral malaria in murine models
THE 72-KDA PROTEIN OF NAEGLERIA FOWLERI PLAYS AN IMPORTANT ROLE IN THE ADHESION OF TROPHOZOITES TO BALB/C MICE NASAL EPITHELIUM
The anti-amoebic activity of Pinus densiflora leaf extract against the brain-eating amoeba Naegleria fowleri
The mRNA content of plasma extracellular vesicles provides a window into molecular processes in the brain during cerebral malaria
The prevention of congenital toxoplasmosis using a combination of Spiramycin and Cotrimoxazole: The long-time experience of a tertiary referral centre
TNFR1 signaling converging on FGF14 controls neuronal hyperactivity and sickness behavior in experimental cerebral malaria
Toxoplasmic encephalitis with high 201Tl uptake and retention mimicking malignant lymphoma in a patient with human immunodeficiency virus infection
Transcriptional responses of brain endothelium to Plasmodium falciparum patient-derived isolates in vitro
Trypanosoma cruzi Central Nervous System Infection-Pathogenesis, Clinical Manifestations, Diagnosis, and Treatment
Unexpected trends of amoebic encephalitis in Pakistan
Unpleasant Souvenir: Imported Plasmodium falciparum Malaria in Türkiye
Unravelling mysteries at the perivascular space: a new rationale for cerebral malaria pathogenesis
Waking up to the Naegleria threat: urgent measures needed to protect public health in Pakistan