Disease: PEPCK 1 deficiency
- A re-assessment of sucrose signaling involved in cluster-root formation and function in phosphate-deficient white lupin (Lupinus albus)
- A1 adenosine receptor allosteric enhancer PD-81723 protects against renal ischemia-reperfusion injury
- Activation of farnesoid X receptor induces RECK expression in mouse liver
- Adaptation of AMPK-mTOR-signal pathways and lipid metabolism in response to low- and high-level rapeseed meal diet in Chinese perch (Siniperca chuatsi)
- Adropin regulates hepatic glucose production via PP2A/AMPK pathway in insulin-resistant hepatocytes
- Alteration of de novo glucose production contributes to fasting hypoglycaemia in Fyn deficient mice
- Application of the split root technique to study iron uptake in cucumber plants
- Astragalus mongholicus powder, a traditional Chinese medicine formula ameliorate type 2 diabetes by regulating adipoinsular axis in diabetic mice
- Boosting Anaplerotic Reactions by Pyruvate Kinase Gene Deletion and Phosphoenolpyruvate Carboxylase Desensitization for Glutamic Acid and Lysine Production in Corynebacterium glutamicum
- Characterization of central carbon metabolism of Streptococcus pneumoniae by isotopologue profiling
- Cytosolic phosphoenolpyruvate carboxykinase deficiency presenting with acute liver failure following gastroenteritis
- Cytosolic Phosphoenolpyruvate Carboxykinase Deficiency: Cause of Hypoglycemia-Induced Seizure and Death
- Cytosolic phosphoenolpyruvate carboxykinase deficiency: Expanding the clinical phenotype and novel laboratory findings
- Deleting pck improves growth and suppresses by-product formation during 1,3-propanediol fermentation by Klebsiella pneumoniae
- Deletion of CD36 gene ameliorates glucose metabolism abnormality induced by high-fat diet and promotes liver lipid accumulation
- Difference in C3-C4 metabolism underlies tradeoff between growth rate and biomass yield in Methylobacterium extorquens AM1
- Differential expression of genes involved in alternative glycolytic pathways, phosphorus scavenging and recycling in response to aluminum and phosphorus interactions in Citrus roots
- Down-regulation of hepatic phosphoenolpyruvate carboxykinase expression in magnesium-deficient rats
- Early life stress interacts with the diet deficiency of omega-3 fatty acids during the life course increasing the metabolic vulnerability in adult rats
- Effect of leptin treatment on mitochondrial function in obese leptin-deficient ob/ob mice
- Effects of ATRAP in Renal Proximal Tubules on Angiotensin-Dependent Hypertension
- Effects of phosphoenolpyruvate carboxylase desensitization on glutamic acid production in Corynebacterium glutamicum ATCC 13032
- Engineered Bacillus subtilis 168 produces L-malate by heterologous biosynthesis pathway construction and lactate dehydrogenase deletion
- Evidence that tolerance of Eutrema salsugineum to low phosphate conditions is hard-wired by constitutive metabolic and root-associated adaptations
- Evolution of pyruvate kinase-deficient Escherichia coli mutants enables glycerol-based cell growth and succinate production
- Expanding the clinical spectrum of cytosolic phosphoenolpyruvate carboxykinase deficiency: novel PCK1 variants in four Arabian Gulf families
- Fe deficiency induced changes in rice (Oryza sativa L.) thylakoids
- Fibroblast growth factor 21 and exercise-induced hepatic mitochondrial adaptations
- Genetic and Pharmacological Inhibition of Autophagy increases the Monoubiquitination of Non-Photosynthetic Phospho<em>enol</em>pyruvate Carboxylase
- Genetic and Pharmacological Inhibition of Autophagy increases the Monoubiquitination of Non-Photosynthetic Phosphoenolpyruvate Carboxylase
- Glucagon receptor knockout mice are protected against acute olanzapine-induced hyperglycemia
- Glucose consumption rate critically depends on redox state in Corynebacterium glutamicum under oxygen deprivation
- GLUT2 proteins and PPARγ transcripts levels are increased in liver of ovariectomized rats: reversal effects of resistance training
- Hepatic cytokine-inducible SH2-containing protein (CISH) regulates gluconeogenesis via cAMP-responsive element binding protein (CREB)
- Hepatic deficiency of Poldip2 in type 2 diabetes dampens lipid and glucose homeostasis
- Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance
- High Protein Diet Feeding Aggravates Hyperaminoacidemia in Mice Deficient in Proglucagon-Derived Peptides
- High selenium impairs hepatic insulin sensitivity through opposite regulation of ROS
- Hydrogen sulphide improves adaptation of Zea mays seedlings to iron deficiency
- Hypocholesterolemic phospholipid transfer protein knockout mice exhibit a normal glucocorticoid response to food deprivation
- Impact of hematopoietic cyclooxygenase-1 deficiency on obesity-linked adipose tissue inflammation and metabolic disorders in mice
- Impact of peripheral ketolytic deficiency on hepatic ketogenesis and gluconeogenesis during the transition to birth
- Inactivation of the adrenergic receptor β2 disrupts glucose homeostasis in mice
- Inducible liver-specific knockdown of protein tyrosine phosphatase 1B improves glucose and lipid homeostasis in adult mice
- Inhibition of gluconeogenic genes by calcium-regulated heat-stable protein 1 via repression of peroxisome proliferator-activated receptor alpha
- Insulin sensitivity improvement of fermented Korean Red Ginseng (Panax ginseng) mediated by insulin resistance hallmarks in old-aged ob/ob mice
- Integrated multi-omics reveals the molecular mechanisms underlying efficient phosphorus use under phosphate deficiency in elephant grass (<em>Pennisetum purpureum</em>)
- Integrated multi-omics reveals the molecular mechanisms underlying efficient phosphorus use under phosphate deficiency in elephant grass (Pennisetum purpureum)
- Interactions between light intensity and phosphorus nutrition affect the phosphate-mining capacity of white lupin (Lupinus albus L.)
- L-Citrulline increases hepatic sensitivity to insulin by reducing the phosphorylation of serine 1101 in insulin receptor substrate-1
- LCAT Enzyme Replacement Therapy Reduces LpX and Improves Kidney Function in a Mouse Model of Familial LCAT Deficiency
- Loss of Nrf2 in mice evokes a congenital intrahepatic shunt that alters hepatic oxygen and protein expression gradients and toxicity
- Low soil available phosphorus level reduces cotton fiber length via osmoregulation
- Magnesium deficiency results in damage of nitrogen and carbon cross-talk of maize and improvement by cerium addition
- Melatonin improved glucose homeostasis is associated with the reprogrammed gut microbiota and reduced fecal levels of short-chain fatty acids in db/db mice
- Meta-analysis of transcriptomic profiles in Dunaliella tertiolecta reveals molecular pathway responses to different abiotic stresses
- Metabolic dysregulation and emerging therapeutical targets for hepatocellular carcinoma
- Metabolic engineering of Lactobacillus plantarum for succinic acid production through activation of the reductive branch of the tricarboxylic acid cycle
- Methyl jasmolate treated buckwheat sprout powder enhances glucose metabolism by potentiating hepatic insulin signaling in estrogen-deficient rats
- Moderate intake of aspartame and sucralose with meals, but not fructose, does not exacerbate energy and glucose metabolism in estrogen-deficient rats
- n-Butylamine production from glucose using a transaminase-mediated synthetic pathway in Escherichia coli
- Novel homozygous PCK1 mutation causing cytosolic phosphoenolpyruvate carboxykinase deficiency presenting as childhood hypoglycemia, an abnormal pattern of urine metabolites and liver dysfunction
- NR6A1 regulates lipid metabolism through mammalian target of rapamycin complex 1 in HepG2 cells
- Nutrient metabolism in the liver and muscle of juvenile blunt snout bream (Megalobrama amblycephala) in response to dietary methionine levels
- Pancreastatin-dependent inflammatory signaling mediates obesity-induced insulin resistance
- Particulate Air pollution mediated effects on insulin resistance in mice are independent of CCR2
- PAS Kinase deficiency alters the glucokinase function and hepatic metabolism
- Pathway construction and metabolic engineering for fermentative production of ectoine in Escherichia coli
- PCK1 attenuates tumor stemness via activating the Hippo signaling pathway in hepatocellular carcinoma
- PCK1 Downregulation Promotes TXNRD1 Expression and Hepatoma Cell Growth via the Nrf2/Keap1 Pathway
- PCK1 is a key regulator of metabolic and mitochondrial functions in renal tubular cells
- PCK2 activation mediates an adaptive response to glucose depletion in lung cancer
- PEPCK-C reexpression in the liver counters neonatal hypoglycemia in Pck1 (del/del) mice, unmasking role in non-gluconeogenic tissues
- PEPCK-C reexpression in the liver counters neonatal hypoglycemia in Pck1 <sup>del/del</sup> mice, unmasking role in non-gluconeogenic tissues
- PEPCK-M expression in mouse liver potentiates, not replaces, PEPCK-C mediated gluconeogenesis
- Phosphoenolpyruvate carboxykinase (PEPCK) deficiency affects the germination, growth and fruit sugar content in tomato (Solanum lycopersicum L.)
- Phosphorus and nitrogen physiology of two contrasting poplar genotypes when exposed to phosphorus and/or nitrogen starvation
- Phosphorus-induced greater enhancement in carbon supply and storage for oil synthesis during the crucial period made cottonseed kernel oil yield have a higher increment than protein
- Potassium deficiency affects the carbon-nitrogen balance in cotton leaves
- PPARγ-induced upregulation of subcutaneous fat adiponectin secretion, glyceroneogenesis and BCAA oxidation requires mTORC1 activity
- Progesterone increases blood glucose via hepatic progesterone receptor membrane component 1 under limited or impaired action of insulin
- Proximal tubule sphingosine kinase-1 has a critical role in A1 adenosine receptor-mediated renal protection from ischemia
- Pyruvate kinase deletion as an effective phenotype to enhance lysine production in Corynebacterium glutamicum ATCC13032: Redirecting the carbon flow to a precursor metabolite
- Redirecting carbon flux through pgi-deficient and heterologous transhydrogenase toward efficient succinate production in Corynebacterium glutamicum
- San-Huang-Tang protects obesity/diabetes induced NAFLD by upregulating PGC-1alpha/PEPCK signaling in obese and galr1 knockout mice models
- San-Huang-Tang protects obesity/diabetes induced NAFLD by upregulating PGC-1α/PEPCK signaling in obese and galr1 knockout mice models
- Scaling with body mass and age in glycolytic enzymes of domestic dogs
- Sexual dimorphic effects of <em>igf1</em> deficiency on metabolism in zebrafish
- Sexual dimorphic effects of igf1 deficiency on metabolism in zebrafish
- Sexual Dimorphism in Circadian Physiology Is Altered in LXRalpha Deficient Mice
- Sexual Dimorphism in Circadian Physiology Is Altered in LXRα Deficient Mice
- Stat3-mediated activation of microRNA-23a suppresses gluconeogenesis in hepatocellular carcinoma by down-regulating glucose-6-phosphatase and peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
- Stepwise metabolic engineering of Corynebacterium glutamicum for the production of phenylalanine
- Suppression of experimental cerebral malaria by disruption of malate:quinone oxidoreductase
- Testosterone modulates renal ammonia metabolism
- The anaplerotic node is essential for the intracellular survival of <em>Mycobacterium tuberculosis</em>
- The Role of Fatty Acid Metabolism in Drug Tolerance of Mycobacterium tuberculosis
- The zinc finger proteins Mxr1p and repressor of phosphoenolpyruvate carboxykinase (ROP) have the same DNA binding specificity but regulate methanol metabolism antagonistically in Pichia pastoris
- Vitamin D Deficiency Increases Lipogenesis and Reduces Beta-Oxidation in the Liver of Diet-Induced Obese Mice
- Vitamin D Deficiency Induces Insulin Resistance and Re-Supplementation Attenuates Hepatic Glucose Output via the PI3K-AKT-FOXO1 Mediated Pathway