• <em>In vitro</em> and <em>in vivo</em> studies on the effect of a mitochondrial fusion promoter on Leydig cell integrity and function
• A detailed review of pharmacology of MFN1 (mitofusion-1)-mediated mitochondrial dynamics: Implications for cellular health and diseases
• A review for the correlation between optic atrophy 1-dependent mitochondrial fusion and cardiovascular disorders
• A Wolfram-like syndrome family: Case report
• Alpha-ketoglutaric acid attenuates oxidative stress and modulates mitochondrial dynamics and autophagy of spleen in a piglet model of lipopolysaccharide-induced sepsis
• Altered Glycolysis, Mitochondrial Biogenesis, Autophagy and Apoptosis in Peritoneal Endometriosis in Adolescents
• An interactive deep learning-based approach reveals mitochondrial cristae topologies
• ARK5 enhances cell survival associated with mitochondrial morphological dynamics from fusion to fission in human multiple myeloma cells
• Association between optic atrophy 1 polymorphisms and primary open angle glaucoma risk: Based on a meta-analysis
• ATF4-dependent increase in mitochondrial-endoplasmic reticulum tethering following OPA1 deletion in skeletal muscle
• Autosomal Dominant MPAN: Mosaicism Expands the Clinical Spectrum to Atypical Late-Onset Phenotypes
• Cardiac-specific PFKFB3 overexpression prevents diabetic cardiomyopathy via enhancing OPA1 stabilization mediated by K6-linked ubiquitination
• Cardiolipin clustering promotes mitochondrial membrane dynamics
• CGRP is essential for protection against alveolar epithelial cell necroptosis by activating the AMPK/L-OPA1 signaling pathway during acute lung injury
• Chinese expert consensus on the clinical diagnosis and treatment of autosomal dominant optic atrophy (2024)
• Clinical features of CAPOS syndrome caused by maternal <em>ATP1A3</em> gene variation: a case report
• Co-occurrence of Mycotoxin-Induced Hepatotoxicity in Mice Inhibited by Lycopene: Mitochondrial Impairment and Early Hepatic Fibrosis
• Creation of an Isogenic Human iPSC-Based RGC Model of Dominant Optic Atrophy Harboring the Pathogenic Variant c.1861C>T (p.Gln621Ter) in the OPA1 Gene
• Dietary alpha-ketoglutarate alleviates Escherichia coli LPS-induced intestinal barrier injury by modulating the endoplasmic reticulum-mitochondrial system pathway in piglets
• Dietary xylo-oligosaccharides alleviates LPS-induced intestinal injury via endoplasmic reticulum-mitochondrial system pathway in piglets
• Dietary α-Ketoglutarate Alleviates Escherichia coli LPS-Induced Intestinal Barrier Injury by Modulating the Endoplasmic Reticulum-Mitochondrial System Pathway in Piglets
• Differentiation activates mitochondrial OPA1 processing in myoblast cell lines
• Digenic FLNA and UCHL1 variants resulting in a complex phenotype
• Dihydromyricetin regulates RIPK3-CaMKII to prevent necroptosis in high glucose-stimulated cardiomyocytes
• Down-regulation of the mitochondrial fusion protein Opa1/Mfn2 promotes cardiomyocyte hypertrophy in Su5416/hypoxia-induced pulmonary hypertension rats
• Downregulation of Mitochondrial Fusion Protein Expression Affords Protection from Canonical Necroptosis in H9c2 Cardiomyoblasts
• Drosophila model to clarify the pathological significance of OPA1 in autosomal dominant optic atrophy
• Drugs targeting TGF-beta/Notch interaction attenuate hypertrophic scar formation by optic atrophy 1-mediated mitochondrial fusion
• Drugs targeting TGF-β/Notch interaction attenuate hypertrophic scar formation by optic atrophy 1-mediated mitochondrial fusion
• Effect of electroacupuncture of Governor Vessel on mitochondrial fusion and proliferation and differentiation of neural stem cells in spinal cord injury rats
• Electroacupuncture protects against cerebral ischemia-reperfusion injury through mitochondrial dynamics
• Empagliflozin impact on experimentally induced acetaminophen toxicity: Imprint of mitochondrial dynamics, biogenesis, and cGAS/STING signal in amending liver insult
• Empagliflozin targets Mfn1 and Opa1 to attenuate microglia-mediated neuroinflammation in retinal ischemia and reperfusion injury
• Establishing induced pluripotent stem cell lines from two dominant optic atrophy patients with distinct <em>OPA1</em> mutations and clinical pathologies
• Family Planning in Genetic Optic Atrophies in Israel, a Case Series and a Discussion of Ethical Considerations
• Flt3 Activation Mitigates Mitochondrial Fragmentation and Heart Dysfunction through Rebalanced L-OPA1 Processing by Hindering the Interaction between Acetylated p53 and PHB2 in Cardiac Remodeling
• GDF15 is required for cold-induced thermogenesis and contributes to improved systemic metabolic health following loss of OPA1 in brown adipocytes
• Genetic diversity of 1,845 rhesus macaques improves genetic variation interpretation and identifies disease models
• Genetic underpinnings explored: OPA1 deletion and complex phenotypes on chromosome 3q29
• High-fat diet causes mitochondrial damage and downregulation of mitofusin-2 and optic atrophy-1 in multiple organs
• HTR1B regulates mitochondrial homeostasis and mitophagy by activating the ERK/ MAPK signalling pathway during human embryonic arrest
• Human neural stem cells promote mitochondrial genesis to alleviate neuronal damage in MPTP-induced cynomolgus monkey models
• Human Platelet Derived Mitochondrial OPA-1 Isoforms and Interaction With TDP-43 in Neurodegenerative Diseases
• Human retinal organoids with an OPA1 mutation are defective in retinal ganglion cell differentiation and function
• Identification of cardioprotective substances in Panax ginseng/P. notoginseng based on mitochondrial morphological characteristics and UPLC-Triple-TOF-MS
• Identifying therapeutic compounds for autosomal dominant optic atrophy (ADOA) through screening in the nematode C. elegans
• In situ architecture of Opa1-dependent mitochondrial cristae remodeling
• Inherited Optic Neuropathies: Real-World Experience in the Paediatric Neuro-Ophthalmology Clinic
• Inhibition of MFN1 restores tamoxifen-induced apoptosis in resistant cells by disrupting aberrant mitochondrial fusion dynamics
• Knock-down of ROCK2 gene improves cognitive function and reduces neuronal apoptosis in AD mice by promoting mitochondrial fusion and inhibiting its division
• Lipidomics reveals the reshaping of the mitochondrial phospholipid profile in cells lacking OPA1 and mitofusins
• Long noncoding RNA H19 promotes vascular calcification by repressing the Bax inhibitor 1/optic atrophy 1 pathway
• Loss and recovery of myocardial mitochondria in mice under different tail suspension time: Apoptosis and mitochondrial fission, fusion and autophagy
• Melatonin Protects Against Mitochondrial Dyshomeostasis and Ovarian Damage Caused by Chronic Unpredictable Mild Stress Through the eIF2α-AFT4 Signaling Pathway in Mice
• Mitochondrial elongation confers protection against doxorubicin-induced cardiotoxicity
• Mitochondrial F0F1-ATP synthase governs the induction of mitochondrial fission
• Mitochondrial OPA1 Deficiency Is Associated to Reversible Defects in Spatial Memory Related to Adult Neurogenesis in Mice
• Mitochondrial transplantation reduces lower limb ischemia-reperfusion injury by increasing skeletal muscle energy and adipocyte browning
• Multi-omics analysis of the oncogenic role of optic <em>atrophy 1</em> in human cancer
• Mutations in human DNA methyltransferase DNMT1 induce specific genome-wide epigenomic and transcriptomic changes in neurodevelopment
• NDV inhibited IFN-β secretion through impeding CHCHD10-mediated mitochondrial fusion to promote viral proliferation
• New therapeutic directions in type II diabetes and its complications: mitochondrial dynamics
• Novel heterozygous OPA3 variant in a family with congenital cataracts, sensorineural hearing loss and neuropathy, without optic atrophy and comparison of pathogenic and population variants
• OMA1-Mediated Mitochondrial Dynamics Balance Organellar Homeostasis Upstream of Cellular Stress Responses
• OPA1 Dominant Optic Atrophy: Pathogenesis and Therapeutic Targets
• OPA1 mutation affects autophagy and triggers senescence in autosomal dominant optic atrophy plus fibroblasts
• Opa1 processing is dispensable in mouse development but is protective in mitochondrial cardiomyopathy
• OPA1 promotes ferroptosis by augmenting mitochondrial ROS and suppressing an integrated stress response
• OPA1, a molecular regulator of dilated cardiomyopathy
• Optic atrophy 1 mediates muscle differentiation by promoting a metabolic switch via the supercomplex assembly factor SCAF1
• Phenotypic variability related to dominant UCHL1 mutations: about three families with optic atrophy and ataxia
• Pioneering PGC-1α-boosted secretome: a novel approach to combating liver fibrosis
• PLAAT1 expression triggers fragmentation of mitochondria in an enzyme activity-dependent manner
• Prenatal exome sequencing for morphologically normal fetus: Should we be doing it?
• Pyrroloquinoline quinone drives ATP synthesis in vitro and in vivo and provides retinal ganglion cell neuroprotection
• Reduced FNDC5-AMPK signaling in diabetic atrium increases the susceptibility of atrial fibrillation by impairing mitochondrial dynamics and activating NLRP3 inflammasome
• Role of mitochondrial fusion proteins MFN2 and OPA1 on lung cellular senescence in chronic obstructive pulmonary disease
• Saponins from <em>Panax japonicus</em> improve neuronal mitochondrial injury of aging rats
• Sectorial Ganglion Cell Complex Thickness as Biomarker of Vision Outcome in Patients With Dominant Optic Atrophy
• Sex-related differences in SIRT3-mediated mitochondrial dynamics in renal ischemia/reperfusion injury
• Short Wavelength Automated Perimetry, Standard Automated Perimetry, and Optical Coherence Tomography in Dominant Optic Atrophy
• SIRT4 is a regulator of human skeletal muscle fatty acid metabolism influencing inner and outer mitochondrial membrane-mediated fusion
• SIRT4 is a regulator of human skeletal muscle fatty acid metabolism influencing inner and outer mitochondrial-mediated fusion
• Sodium butyrate improves renal injury in diabetic nephropathy through AMPK/SIRT1/PGC-1α signaling pathway
• Structural mechanism of mitochondrial membrane remodelling by human OPA1
• Suvorexant improves mitochondrial dynamics with the regulation of orexinergic and mTOR activation in rats exhibiting PTSD-like symptoms
• Targeting DRP1 with Mdivi-1 to correct mitochondrial abnormalities in ADOA plus syndrome
• Targeting DRP1 with Mdivi-1 to correct mitochondrial abnormalities in ADOA+ syndrome
• The Effect of Cold-Water Swimming on Energy Metabolism, Dynamics, and Mitochondrial Biogenesis in the Muscles of Aging Rats
• The human OPA1^delTTAG mutation induces adult onset and progressive auditory neuropathy in mice
• The mitochondrial fusion protein OPA1 is dispensable in the liver and its absence induces mitohormesis to protect liver from drug-induced injury
• The mutation R107Q alters mtSSB ssDNA compaction ability and binding dynamics
• The Role of Mitochondrial Dynamics and Mitotic Fission in Regulating the Cell Cycle in Cancer and Pulmonary Arterial Hypertension: <em>Implications for Dynamin-Related Protein 1 and Mitofusin2 in Hyperproliferative Diseases</em>
• The Role of Swelling in the Regulation of OPA1-Mediated Mitochondrial Function in the Heart In Vitro
• TRPA1 promotes cisplatin-induced acute kidney injury via regulating the endoplasmic reticulum stress-mitochondrial damage
• TRPA1-PI3K/Akt-OPA1-ferroptosis axis in ozone-induced bronchial epithelial cell and lung injury
• Visual Function and Inner Retinal Structure in Relation to Birth Factors in Autosomal Dominant Optic Atrophy
• Wolfram-like syndrome: a case report
• Yo-yo Dieting Delays Male Drosophila melanogaster Aging Through Enhanced Mitochondrial Function, Relative to Sustained High-Calorie Diet Feeding
• β-asarone improves cognitive impairment and alleviates autophagy in mice with vascular dementia via the cAMP/PKA/CREB pathway