• A case of cryopyrin-associated periodic syndrome due to somatic mosaic mutation complicated with recurrent circinate erythematous psoriasis
• A Knock-In Mouse Model of Cryopyrin-Associated Periodic Syndromes
• A novel Nlrp3 knock-in mouse model with hyperactive inflammasome in development of lethal inflammation
• A Retrospective Patient Chart Review and Survey in Patients with Cryopyrin-associated Periodic Syndromes Treated with Anakinra
• Adult patient diagnosed with Muckle-Wells syndrome, antiphospholipid syndrome and glomerular haematuria
• Antisense Oligonucleotide Therapy Decreases IL-1β Expression and Prolongs Survival in Mutant Nlrp3 Mice
• CANE, a Component of the NLRP3 Inflammasome, Promotes Inflammasome Activation
• Case Report: A <em>de novo NLRP3</em> variant resulting in autoinflammatory disease in a Chinese newborn
• Case Report: Efficacy, safety, and favorable long-term outcome of early treatment with IL-1 inhibitors in a patient with chronic infantile neurological cutaneous articular (CINCA) syndrome caused by NLRP3 mosaicism
• Case report: The altered rate of monocytic cell death in a patient of Muckle-Wells syndrome with atypical clinical course
• Clinical and Genetic Spectrum of Nine Cases of NLRP3-Associated Autoinflammatory Disease (NLRP3-AID) and Identification of One Novel NLRP3 Mutation by Genetic Variation Analyses
• Clinical characteristics of Chinese neonates with neonatal-onset multisystem inflammatory disease: a case report and literature review
• Clinical Characteristics of Cryopyrin-Associated Periodic Syndrome and Long-Term Real-World Efficacy and Tolerability of Canakinumab in Japan: Results of a Nationwide Survey
• Clinical presentation and genetic variants in patients with autoinflammatory diseases: results from the German GARROD registry
• Cold hypersensitivity in the hands and feet is associated with erectile dysfunction in young Taiwanese men
• Complex regulation of alarmins S100A8/A9 and secretion via gasdermin D pores exacerbates autoinflammation in familial Mediterranean fever
• Constitutive IL-1RA production by modified immune cells protects against IL-1-mediated inflammatory disorders
• Cracking the NLRP3 code: Pioneering precision medicine for inflammation
• Cryopyrin-associated periodic fever syndrome (CAPS) presenting as early-onset dementia, lacking typical recurrent fever or skin rash: a case report
• Diagnosis traps for patients with acquired NLRP3 mutation
• Discovery of a novel missense variant in NLRP3 causing atypical CAPS with hearing loss as the primary presentation, responsive to anti-IL-1 therapy
• Discovery of a Novel Missense Variant in NLRP3 Causing Atypical Cryopyrin-Associated Periodic Syndromes With Hearing Loss as the Primary Presentation, Responsive to Anti-Interleukin-1 Therapy
• Efficacy and safety of thalidomide in children with monogenic autoinflammatory diseases: a single-center, real-world-evidence study
• Evaluation of common NLRP3 Q703K variant in pediatric patients with autoinflammatory disease: CAPS and PFAPA
• Exploratory study of cold hypersensitivity in Japanese women: genetic associations and somatic symptom burden
• Expression of MHC II in DRG neurons attenuates paclitaxel-induced cold hypersensitivity in male and female mice
• Genetic variations in NLRP3 and NLRP12 genes in adult-onset patients with autoinflammatory diseases: a comparative study
• Glucose-oxygen deprivation constrains HMGCR function and Rac1 prenylation and activates the NLRP3 inflammasome in human monocytes
• HSP90β controls NLRP3 autoactivation
• Identification of a variant in NLRP3 gene in a patient with Muckle-Wells syndrome: a case report and review of literature
• Identifying high-risk neurological phenotypes in adult-onset classic monogenic autoinflammatory diseases: when should neurologists consider testing?
• Inflammasome activity is controlled by ZBTB16-dependent SUMOylation of ASC
• Isoliquiritigenin inhibits NLRP3 inflammasome activation with CAPS mutations by suppressing caspase-1 activation and mutated NLRP3 aggregation
• JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders
• KCNN4 links PIEZO-dependent mechanotransduction to NLRP3 inflammasome activation
• Kidney Involvement in Autoinflammatory Diseases
• Lipids in inflammasome activation and autoinflammatory disorders
• Long-term renal outcome of Cryopyrin-associated periodic syndrome (CAPS) under anti-Interleukin-1 therapy
• Long-term safety and effectiveness of canakinumab in patients with monogenic autoinflammatory diseases: results from the interim analysis of the RELIANCE registry
• Low-level NLRP3 somatic mosaicism in adult-onset cryopyrin-associated periodic syndrome misdiagnosed as chronic urticaria
• Low-level NRLP3 somatic mosaicism in adult-onset cryopyrin-associated periodic syndrome misdiagnosed as chronic urticaria
• Megakaryocyte NLRP3 hyperactivation induces mild anemia and potentiates inflammatory response in mice
• Neutrophilic Urticarial Dermatosis
• NLRC4 gain-of-function variant is identified in a patient with systemic lupus erythematosus
• NLRP12-associated autoinflammatory disease: much more than the FCAS phenotype
• No NLRP3 inflammasome activity in kidney epithelial cells, not even when the NLRP3-A350V Muckle-Wells variant is expressed in podocytes of diabetic mice
• Non-invasive load monitoring based on deep learning to identify unknown loads
• Ocular involvement in adult and paediatric patients with monogenic autoinflammatory diseases: a Spanish multicentre retrospective study
• Optical coherence tomography assessment of disease activity in cryopyrin-associated periodic syndrome
• Papilledema as a possible key sign for diagnosis of cryopyrin-associated periodic syndromes (CAPS): A case report
• Parthenolide targets NLRP3 to treat inflammasome-related diseases
• Pathogenic NLRP3 mutants form constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1β production
• Pharmacology of a Potent and Novel Inhibitor of the NOD-Like Receptor Pyrin Domain-Containing Protein 3 (NLRP3) Inflammasome that Attenuates Development of Nonalcoholic Steatohepatitis and Liver Fibrosis
• Practical Approach to Diagnosis and Management of IL-1-Mediated Autoinflammatory Diseases (CAPS, TRAPS, MKD, and DIRA)
• Refining Treat-to-Target (T2T) strategies in Cryopyrin-Associated Periodic Syndromes (CAPS): The role of inflammatory markers
• Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ZY-IL1 in Three Patients with Cryopyrin-Associated Periodic Syndromes
• Similarities and differences in autoinflammatory diseases with urticarial rash, cryopyrin-associated periodic syndrome and Schnitzler syndrome
• Single-cell transcriptomic analysis in two patients with rare systemic autoinflammatory diseases treated with anti-TNF therapy
• Socio-professional impact and quality of life of cryopyrin-associated periodic syndromes in 54 patients in adulthood
• Species-specific NLRP3 regulation and its role in CNS autoinflammatory diseases
• Subcutaneous administration of a novel TRPM8 antagonist reverses cold hypersensitivity while attenuating the drop in core body temperature
• The assessment of autoinflammatory disease classification criteria (Eurofever/PRINTO) in a real-life cohort
• The discovery of NLRP3 and its function in cryopyrin-associated periodic syndromes and innate immunity
• The genetic and clinical characteristics and effects of Canakinumab on cryopyrin-associated periodic syndrome: a large pediatric cohort study from China
• The most frequent febrile syndromes and autoinflammatory diseases in adulthood
• The phenotype and genotype of Chinese adult patients with NLRP3-associated autoinflammatory disease
• The Potential of NOD-like Receptor Protein 3 Inflammasome Inhibitors in the Treatments of Diseases
• The Role of <em>Hemophilus influenzae</em> Infection and Its Relationship With Colorectal Cancer
• Uncoupled pyroptosis and IL-1β secretion downstream of inflammasome signaling
• Update on ocular manifestations of the main monogenic and polygenic autoinflammatory diseases