• <em>KCNQ1</em> and Long QT Syndrome in 1/45 Amish: The Road From Identification to Implementation of Culturally Appropriate Precision Medicine
• A computational analysis of the effect of sevoflurane in a human ventricular cell model of long QT syndrome: Importance of repolarization reserve in the QT-prolonging effect of sevoflurane
• A mild phenotype associated with KCNQ1 p.V205M mediated long QT syndrome in First Nations children of Northern British Columbia: effect of additional variants and considerations for management
• A mutation in the cardiac KV7.1 channel possibly disrupts interaction with Yotiao protein
• A novel mutation KCNQ1p.Thr312del is responsible for long QT syndrome type 1
• A novel stop-gain pathogenic variant in the KCNQ1 gene causing long QT syndrome 1
• A pore-localizing CACNA1C-E1115K missense mutation, identified in a patient with idiopathic QT prolongation, bradycardia, and autism spectrum disorder, converts the L-type calcium channel into a hybrid nonselective monovalent cation channel
• Accelerated QT adaptation following atropine-induced heart rate increase in LQT1 patients versus healthy controls: A sign of disturbed hysteresis
• Altered mechano-electrical coupling: An underappreciated factor in sympathetically mediated torsades de pointes in the long QT(1) syndrome
• Altered mechano-electrical coupling: An underappreciated factor in sympathetically mediated torsades de pointes in the long QT₁ syndrome
• Analysis of the KCNQ1 gene mutation in 2 families with congenital long QT syndrome type 1 in Xinjiang Uygur Autonomous Region
• Association of the P441L KCNQ1 variant with severity of long QT syndrome and risk of cardiac events
• Beckwith-Wiedemann syndrome with long QT caused by a deletion involving KCNQ1 but not KCNQ1OT1:TSS-DMR
• Cardiac Arrest Following Torsades de Pointes Caused by Hypokalemia and Catecholamines in a Patient with Congenital Long QT Syndrome Type 1 After Surgical Aortic Valve Replacement: A Case Report
• Cardiac electrical and mechanical alterations - united in the long QT syndrome
• Cardiac microtissues from human pluripotent stem cells recapitulate the phenotype of long-QT syndrome
• Cardiac response to water activities in children with Long QT syndrome type 1
• Case report: A 56-year-old woman presenting with torsades de pointes and cardiac arrest associated with levosimendan administration and underlying congenital long QT syndrome type 1
• Clinical characterization of type 1 long QT syndrome caused by C-terminus Kv7.1 variants
• Comparison of automated interval measurements by widely used algorithms in digital electrocardiographs
• Compound Heterozygous <em>KCNQ1</em> Mutations Causing Recessive Romano-Ward Syndrome: Functional Characterization by Mutant Co-expression
• Compound Heterozygous KCNQ1 Mutations Causing Recessive Romano-Ward Syndrome: Functional Characterization by Mutant Co-expression
• Computational Study on Effect of KCNQ1 P535T Mutation in a Cardiac Ventricular Tissue
• Concealed long QT syndrome type 1
• Congenital Long QT Syndrome: A Review of Genetic and Pathophysiologic Etiologies, Phenotypic Subtypes and Clinical Management
• Corrigendum to "A challenge for mutation specific risk stratification in long QT syndrome type 1" [J. Cardiol. 72(1) (2018) 56-65]
• Differential Diagnosis Between Catecholaminergic Polymorphic Ventricular Tachycardia and Long QT Syndrome Type 1 - Modified Schwartz Score
• Divergent regulation of KCNQ1/E1 by targeted recruitment of protein kinase A to distinct sites on the channel complex
• Electro-mechanical (dys-)function in long QT syndrome type 1
• Enhancing the interpretation of genetic observations in KCNQ1 in unselected populations: relevance to secondary findings
• Epilepsy in patients with long QT syndrome type 1: A Norwegian family
• Erratum to "Optical Recording of Action Potentials in Human Induced Pluripotent Stem Cell-Derived Cardiac Single Cells and Monolayers Generated from Long QT Syndrome Type 1 Patients"
• Establishment of a human induced pluripotent stem cell line, KSCBi015-A, from a long QT syndrome type 1 patient harboring a KCNQ1 mutation
• Estimating the probability of early afterdepolarizations and predicting arrhythmic risk associated with long QT syndrome type 1 mutations
• Extensive Diversity of Molecular Mechanisms Underlying the Congenital Long QT Syndrome Type 1
• Functional Characterization of a Spectrum of Novel Romano-Ward Syndrome <em>KCNQ1</em> Variants
• Functional Characterization of a Spectrum of Novel Romano-Ward Syndrome KCNQ1 Variants
• Functional hyperactivity in long QT syndrome type 1 pluripotent stem cell-derived sympathetic neurons
• Functionally Aberrant Mutant KCNQ1 With Intermediate Heterozygous and Homozygous Phenotypes
• Generation and characterization of the human induced pluripotent stem cell (hiPSC) line NCUFi001-A from a patient carrying KCNQ1 G314S mutation
• Generation and characterization of twelve human induced pluripotent stem cell (iPSC) lines from four familial long QT syndrome type 1 (LQT1) patients carrying KCNQ1 c.1201dupC mutation
• Generation of a human embryonic stem cell line WAe009-A-79 carrying a long QT syndrome mutation in KCNQ1
• Generation of a human induced pluripotent stem cell line (JSPHi002-A) from a patient with long-QT syndrome type 1 caused by KCNQ1 c.773A &gt; T mutation
• Generation of a human induced pluripotent stem cell line (JSPHi002-A) from a patient with long-QT syndrome type 1 caused by KCNQ1 c.773A > T mutation
• Generation of eight human induced pluripotent stem cell (iPSC) lines from familial Long QT Syndrome type 1 (LQT1) patients carrying KCNQ1 c.1697C&gt;A mutation (NUIGi005-A, NUIGi005-B, NUIGi005-C, NUIGi006-A, NUIGi006-B, NUIGi006-C, NUIGi007-A, and NU
• Generation of eight human induced pluripotent stem cell (iPSC) lines from familial Long QT Syndrome type 1 (LQT1) patients carrying KCNQ1 c.1697C>A mutation (NUIGi005-A, NUIGi005-B, NUIGi005-C, NUIGi006-A, NUIGi006-B, NUIGi006-C, NUIGi007-A, and NUIGi0
• Generation of patient-specific induced pluripotent stem cell lines from one patient with Jervell and Lange-Nielsen syndrome, one with type 1 long QT syndrome and two healthy relatives
• Generation of the human induced pluripotent stem cell (hiPSC) line PSMi004-A from a carrier of the KCNQ1-R594Q mutation
• Generation of the human induced pluripotent stem cell (hiPSC) line PSMi005-A from a patient carrying the KCNQ1-R190W mutation
• Generation of the human induced pluripotent stem cell (hiPSC) line PSMi006-A from a patient affected by an autosomal recessive form of long QT syndrome type 1
• Generation of the human induced pluripotent stem cell (hiPSC) line PSMi007-A from a Long QT Syndrome type 1 patient carrier of two common variants in the NOS1AP gene
• Generation of three induced pluripotent stem cell lines (SCVIi014-A, SCVIi015-A, and SCVIi016-A) from patients with LQT1 caused by heterozygous mutations in the KCNQ1 gene
• Genetic characterization of KCNQ1 variants improves risk stratification in type 1 long QT syndrome patients
• Genetic testing in Polynesian long QT syndrome probands reveals a lower diagnostic yield and an increased prevalence of rare variants
• Head-up tilt test induces T-wave alternans in long QT syndrome with KCNQ1 gene mutation: Case report CARE-compliant article
• Human Induced Pluripotent Stem Cell-Derived Engineered Heart Tissue as a Sensitive Test System for QT Prolongation and Arrhythmic Triggers
• I_Ks Activator ML277 Mildly Affects Repolarization and Arrhythmic Outcome in the CAVB Dog Model
• I_Ks inhibitor JNJ303 prolongs the QT interval and perpetuates arrhythmia when combined with enhanced inotropy in the CAVB dog
• Identification of a Novel KCNQ1 Frameshift Mutation and Review of the Literature among Iranian Long QT Families
• Impaired Adrenergic/Protein Kinase A Response of Slow Delayed Rectifier Potassium Channels as a Long QT Syndrome Motif: Importance and Unknowns
• Implantable loop recorder uncovered torsades de pointes in long-QT syndrome type 1 with multi cause of syncope
• Independent validation and clinical implications of the risk prediction model for long QT syndrome (1-2-3-LQTS-Risk)
• Information Flow Between Heart Rhythm, Repolarization, and the Diastolic Interval Series for Healthy Individuals and LQTS1 Patients
• Interactions between KCNQ1 and KCNH2 may modulate the long QT type 1 phenotype
• KCNQ1 and Long QT Syndrome in 1/45 Amish: The Road From Identification to Implementation of Culturally Appropriate Precision Medicine
• KCNQ1-deficient and KCNQ1-mutant human embryonic stem cell-derived cardiomyocytes for modeling QT prolongation
• Left Cardiac Sympathetic Denervation Monotherapy in Patients With Congenital Long QT Syndrome
• Long QT syndrome type 1 and 2 patients respond differently to arrhythmic triggers: The TriQarr in vivo study
• Long QT Syndrome Type 1 in an Australian Indigenous Patient
• Low Baseline Fetal Heart Rate Leads to Diagnosis of Long QT Syndrome Type 1
• Molecular Mechanism of Autosomal Recessive Long QT-Syndrome 1 without Deafness
• Mutation location and IKs regulation in the arrhythmic risk of long QT syndrome type 1: the importance of the KCNQ1 S6 region
• Mutation-Specific Differences in Kv7.1 (<em>KCNQ1</em>) and Kv11.1 (<em>KCNH2</em>) Channel Dysfunction and Long QT Syndrome Phenotypes
• Mutation-Specific Differences in Kv7.1 (KCNQ1) and Kv11.1 (KCNH2) Channel Dysfunction and Long QT Syndrome Phenotypes
• Mutational and phenotypic spectra of KCNE1 deficiency in Jervell and Lange-Nielsen Syndrome and Romano-Ward Syndrome
• No beneficial use of the wearable cardioverter defibrillator among patients suffering from inherited and congenital heart disease: data from a European multicenter registry
• NOS1AP polymorphisms reduce NOS1 activity and interact with prolonged repolarization in arrhythmogenesis
• Optical Recording of Action Potentials in Human Induced Pluripotent Stem Cell-Derived Cardiac Single Cells and Monolayers Generated from Long QT Syndrome Type 1 Patients
• Outcome by Sex in Patients With Long QT Syndrome With an Implantable Cardioverter Defibrillator
• Proarrhythmic proclivity of left-stellate ganglion stimulation in a canine model of drug-induced long-QT syndrome type 1
• QT correction using Bazett's formula remains preferable in long QT syndrome type 1 and 2
• Recurrent Torsades with Refractory QT Prolongation in a 54-Year-Old Man
• Retraction of: Systematic Evaluation of KCNQ1 variant using ACMG/AMP Guidelines and Risk Stratification in Long QT Syndrome Type 1
• Seizure-induced Torsades de pointes:In a canine drug-induced long-QT1 model
• Sex hormones and repolarization dynamics during the menstrual cycle in women with congenital long QT syndrome
• shRNAs Targeting a Common <em>KCNQ1</em> Variant Could Alleviate Long-QT1 Disease Severity by Inhibiting a Mutant Allele
• Sigma non-opioid receptor 1 is a potential therapeutic target for long QT syndrome
• Spatio-temporal repolarization dispersion before and after exercise in patients with long QT syndrome type 1 vs controls - probing into the arrhythmia substrate
• Spatiotemporal repolarization dispersion before and after exercise in patients with long QT syndrome type 1 versus controls: probing into the arrhythmia substrate
• Suppression-Replacement <em>KCNQ1</em> Gene Therapy for Type 1 Long QT Syndrome
• Suppression-Replacement KCNQ1 Gene Therapy for Type 1 Long QT Syndrome
• Systematic Evaluation of <em>KCNQ1</em> Variant Using ACMG/AMP Guidelines and Risk Stratification in Long QT Syndrome Type 1
• Systematic Evaluation of KCNQ1 Variant Using ACMG/AMP Guidelines and Risk Stratification in Long QT Syndrome Type 1
• Systematic Evaluation of KCNQ1 variant using ACMG/AMP Guidelines and Risk Stratification in Long QT Syndrome Type 1: Expression of Concern
• Targeting the I_Ks Channel PKA Phosphorylation Axis to Restore Its Function in High-Risk LQT1 Variants
• The fully activated open state of KCNQ1 controls the cardiac "fight-or-flight" response
• The Pathological Mechanisms of Hearing Loss Caused by <em>KCNQ1</em> and <em>KCNQ4</em> Variants
• They Are Not Monozygotic Twins - Long QT Syndrome Type 1 (LQT1) and Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)
• To Modify or Not to Modify: Allele-Specific Effects of 3'UTR-<em>KCNQ1</em> Single Nucleotide Polymorphisms on Clinical Phenotype in a Long QT 1 Founder Population Segregating a Dominant-Negative Mutation
• Unlocking the Potential of Left Cardiac Sympathetic Denervation: A Scoping Review of a Promising Approach for Long QT Syndrome