• A Case of Hypophosphatasia With Normal Alkaline Phosphatase Levels
• A case report of odonto-hypophosphatasia with a novel variant in the <em>ALPL</em> gene
• A case report of odonto-hypophosphatasia with a novel variant in the ALPL gene
• A Delphi panel to build consensus on assessing disease severity and disease progression in adult patients with hypophosphatasia in the United States
• A Novel Case of Concomitant PHEX and ALPL Mutation In a Family With Rickets
• A probable case of hypophosphatasia in St Bride's Lower Churchyard (1770-1849, London, UK)
• A Review of Selected Dental Anomalies With Histologic Features in the Pediatric Patient
• A unique case of childhood hypophosphatasia caused by a novel heterozygous 51-bp in-frame deletion in the <em>ALPL</em> gene
• A unique case of childhood hypophosphatasia caused by a novel heterozygous 51-bp in-frame deletion in the ALPL gene
• Acalvaria: the first case report from Nepal
• Advances in Immune Tolerance Induction in Enzyme Replacement Therapy
• ALPL regulates pro-angiogenic capacity of mesenchymal stem cells through ATP-P2X7 axis controlled exosomes secretion
• Atypical Femoral Fracture in Hypophosphatasia: A Systematic Review
• Calcium Pyrophosphate Crystal Deposition: Insights to Risks Factors and Associated Conditions
• Calcium pyrophosphate deposition disease
• Case Report of a 4-Year-Old Girl with Stage IV Grade C Localized Periodontitis (Pre-Puberal Localized Aggressive Periodontitis) Affected by Misrecognition and Late Diagnosis
• Catalyzing precision: unraveling the diagnostic conundrum of tunisian familial hypophosphatasia case through integrative clinical and molecular approaches
• Challenges in Hypophosphatasia: Suspicion, Diagnosis, Genetics, Management, and Follow-Up
• Chylous ascites complicating perinatal severe hypophosphatasia in an infant on high-setting ventilation and enzyme replacement therapy
• Clinical and molecular description of the first Italian cohort of 33 subjects with hypophosphatasia
• Clinical Profiles of Children with Hypophosphatasia prior to Treatment with Enzyme Replacement Therapy: An Observational Analysis from the Global HPP Registry
• Clinical utility of comprehensive gene panel testing for common and rare causes of skeletal dysplasia and other skeletal disorders: Results from the largest cohort to date
• Combination of osteogenesis imperfecta and hypophosphatasia in three children with multiple fractures, low bone mass and severe osteomalacia, a challenge for therapeutic management
• Compromised Muscle Properties in a Severe Hypophosphatasia Murine Model
• Correction to: The diagnosis of hypophosphatasia in children as a multidisciplinary effort: an expert opinion
• Correction: Hypophosphatasia diagnosis: current state of the art and proposed diagnostic criteria for children and adults
• Could Some Patients With Fibromyalgia Potentially Have Hypophosphatasia? A Retrospective Single-Center Study
• Cranial Neural Crest Specific Deletion of <em>Alpl</em> (TNAP) via P0-Cre Causes Abnormal Chondrocyte Maturation and Deficient Cranial Base Growth
• Craniosynostosis in primary metabolic bone disorders: a single-institution experience
• Current status of <em>N</em>-, <em>O</em>-, <em>S</em>-heterocycles as potential alkaline phosphatase inhibitors: a medicinal chemistry overview
• Cutaneous lesions in the setting of hypophosphatasia
• Dental characteristics of patients with four different types of skeletal dysplasias
• Detection of hypophosphatasia in hospitalised adults in rheumatology and internal medicine departments: a multicentre study over 10 years
• Diagnosis and initial management of children presenting with premature loss of primary teeth associated with a systemic condition: A scoping review and development of clinical aid
• Diagnosis and treatment of adult hypophosphatasia: Still a big challenge?
• Diagnostic and New Therapeutic Approaches to Two Challenging Pediatric Metabolic Bone Disorders: Hypophosphatasia and X-linked Hypophosphatemic Rickets
• Diffusion tensor imaging shows increased physis organization after growth hormone initiation in hypophosphatasia
• Effect of Asfotase Alfa in the Treatment of Hypophosphatasia- A Systematic Review
• Effectiveness of asfotase alfa for treatment of adults with hypophosphatasia: results from a global registry
• Effects of asfotase alfa in adults with pediatric-onset hypophosphatasia over 24 months of treatment
• Efficacy and safety of asfotase alfa in patients with hypophosphatasia: A systematic review
• Enzyme replacement therapy for hypophosphatasia-The current paradigm
• First Reported Case of a Pyrophosphate Kidney Stone in a Human
• First reported magnesium pyrophosphate kidney stone prompts diagnosis of hypophosphatasia
• Genetic profile of a large Spanish cohort with hypercalcemia
• Health-related quality of life and fatigue in adult rare bone disease patients: A cross-sectional study from Austria
• Hypoalkaline Phosphatemia Dental Type: A Case Report
• Hypophosphatasia diagnosis: current state of the art and proposed diagnostic criteria for children and adults
• Hypophosphatasia Presenting as a Chronic Diffuse Pain Syndrome with Extra-Articular Calcifications
• Hypophosphatasia: from birth to adulthood
• Hypophosphatasia: presentation and response to asfotase alfa
• Impact of Restricted Phosphorus, Calcium-adjusted Diet on Musculoskeletal and Mental Health in Hypophosphatasia
• Impressive clinical improvement and disappearance of neuropathic pain in an adult patient with hypophosphatasia treated with asfotase alfa
• Improvement in quality of life after asfotase alfa treatment in adults with pediatric-onset hypophosphatasia: data from 5 patient-reported outcome measures
• Improving care pathways for people living with rare bone diseases (RBDs): outcomes from the first RBD Summit
• Inherited phosphate and pyrophosphate disorders: New insights and novel therapies changing the oral health landscape
• Integrated Applied Clinical Pharmacology in the Advancement of Rare and Ultra-Rare Disease Therapeutics
• Joint manifestations revealing inborn metabolic diseases in adults: a narrative review
• Latent metabolic bone disease, skeletal dysplasia and other conditions related to low bone formation among 38 patients with subtrochanteric femoral fractures: a retrospective observational study
• Management of Craniosynostosis in Lethal Perinatal Hypophosphatasia
• Mild hypophosphatasia may be twice as prevalent as previously estimated: an effective clinical algorithm to detect undiagnosed cases
• Monoclonal antibody anti-sclerostin for treatment of pelvic insufficiency fractures in adult hypophosphatasia: A case report
• Musculoskeletal and neurocognitive clinical significance of adult hypophosphatasia
• Musculoskeletal pain and muscular weakness as the main symptoms of adult hypophosphatasia in a Spanish cohort: clinical characterization and identification of a new ALPL gene variant
• New Empirical Bayes Models to Jointly Analyze Multiple RNA-Sequencing Data in a Hypophosphatasia Disease Study
• New insights into the landscape of ALPL gene variants in patients with hypophosphatasia from the Global HPP Registry
• Nomogram for predicting early hypophosphatemia in term infants
• Nutritional Behavior of Patients with Bone Diseases: A Cross-Sectional Study from Austria
• Odontohypophosphatasia caused by a novel combination of two heterozygous variants: a case report
• On pathways and blind alleys-The importance of biomarkers in vitamin B₆ -dependent epilepsies
• Orodental phenotype and genotype findings in 8 Chinese children with hypophosphatasia
• Patient-derived reference intervals for alkaline phosphatase to support appropriate utility for isoenzymes determinations and hypophosphatasia
• Pediatric hypophosphatasia: avoid diagnosis missteps!
• Persistent hypercalcemia mimicking hypophosphatasia after discontinuation of a ketogenic diet: a case report
• Preclinical rodent models for human bone disease including a focus on cortical bone
• Preclinical Rodent Models for Human Bone Disease, Including a Focus on Cortical Bone
• Prenatal asfotase alfa-mediated enzyme replacement therapy restores delayed calcification in a severe infantile form of hypophosphatasia model mice
• Proceedings of the 2023 Santa Fe Bone Symposium: Progress and Controversies in the Management of Patients with Skeletal Diseases
• Proposed diagnostic criteria for the diagnosis of hypophosphatasia in children and adolescents: results from the HPP International Working Group
• Pyridoxine challenge reflects pediatric hypophosphatasia severity and thereby examines tissue-nonspecific alkaline phosphatase's role in vitamin B(6) metabolism
• Pyridoxine challenge reflects pediatric hypophosphatasia severity and thereby examines tissue-nonspecific alkaline phosphatase's role in vitamin B₆ metabolism
• Rare Causes of Musculoskeletal Pain: Thinking beyond Common Rheumatologic Diseases
• Role of PLP-Level as a predictive marker for oral health status in adult hypophosphatasia
• Safety, Pharmacokinetics, and Pharmacodynamics of Efzimfotase Alfa, a Second-generation Enzyme Replacement Therapy: Phase 1, Dose-escalation Study in Adults with Hypophosphatasia
• Serum alkaline phosphatase can be elevated in patients with hypophosphatasia due to liver disease
• Short stature with low serum alkaline phosphatase activity: a case report of hypophosphatasia
• Skeletal indicators of pathology in the context of early tooth loss in children: A systematic literature review
• Subnormal Serum Liver Enzyme Levels: A Review of Pathophysiology and Clinical Significance
• Systemic effects of hypophosphatasia characterization of two novel variants in the <em>ALPL</em> gene
• Systemic effects of hypophosphatasia characterization of two novel variants in the ALPL gene
• The challenge of hypophosphatasia diagnosis in adults: results from the HPP International Working Group Literature Surveillance
• The diagnosis of hypophosphatasia in children as a multidisciplinary effort: an expert opinion
• The Effect of Asfotase Alfa on Plasma and Urine Pyrophosphate Levels and Pseudofractures in a Patient With Adult-Onset Hypophosphatasia
• The Global ALPL gene variant classification project: Dedicated to deciphering variants
• The odontoblastic differentiation of dental mesenchymal stem cells: molecular regulation mechanism and related genetic syndromes
• The structural pathology for hypophosphatasia caused by malfunctional tissue non-specific alkaline phosphatase
• Use of Complementary and Alternative Medicine in Patients with Rare Bone Diseases and Osteoporosis
• What the pediatric endocrinologist needs to know about skeletal dysplasia, a primer
• Zinc and vitamin D deficiency and supplementation in hypophosphatasia patients - A retrospective study
• Τhe story of sclerostin inhibition: the past, the present, and the future