• A Genetic Analysis of the <em>Caenorhabditis elegans</em> Detoxification Response
• A Possible Anti-Inflammatory Effect of Proline in the Brain Cortex and Cerebellum of Rats
• Acetylcholinesterase activity as a neurotoxicity marker within the context of experimentally-simulated hyperprolinaemia: An in vitro approach
• Acute encephalopathy associated with influenza virus infection in a patient with hyperprolinaemia type II
• alpha-Tocopherol and ascorbic acid prevent memory deficits provoked by chronic hyperprolinemia in rats
• An interictal schizophrenia-like psychosis in an adult patient with 22q11.2 deletion syndrome
• Analysis and update of the human aldehyde dehydrogenase (ALDH) gene family
• Analysis of 26 amino acids in human plasma by HPLC using AQC as derivatizing agent and its application in metabolic laboratory
• Antioxidant Therapy in a Patient with Hyperprolinemia Type 1 Presenting with Mild Neuromotor Retardation and Speech Disturbance
• Behavioral and neurochemical effects of proline
• Behavioral changes induced by long-term proline exposure are reversed by antipsychotics in zebrafish
• Biochemical and clinical features of hereditary hyperprolinemia
• Chronic hyperprolinemia provokes a memory deficit in the Morris water maze task
• Comparative aspects of tissue glutamine and proline metabolism
• Crosstalk Among Disrupted Glutamatergic and Cholinergic Homeostasis and Inflammatory Response in Mechanisms Elicited by Proline in Astrocytes
• Crystal structure of Thermus thermophilus Delta1-pyrroline-5-carboxylate dehydrogenase
• Cytoskeleton of cortical astrocytes as a target to proline through oxidative stress mechanisms
• Disorders affecting vitamin B₆ metabolism
• Drosophila delta-1-pyrroline-5-carboxylate dehydrogenase (P5CDh) is required for proline breakdown and mitochondrial integrity-Establishing a fly model for human type II hyperprolinemia
• Early neurological phenotype in 4 children with biallelic PRODH mutations
• Effect of hyperprolinemia on acetylcholinesterase and butyrylcholinesterase activities in rat
• Effect of Proline on Cell Death, Cell Cycle, and Oxidative Stress in C6 Glioma Cell Line
• Effects of chronic proline administration on lipid contents of rat brain
• Elevated creatinine in a patient on IVIG-therapy
• Epilepsy Phenotypes of Vitamin B6-Dependent Diseases: An Updated Systematic Review
• Evidence for association of hyperprolinemia with schizophrenia and a measure of clinical outcome
• Evidence that hyperprolinemia alters glutamatergic homeostasis in rat brain: neuroprotector effect of guanosine
• Experimental hyperprolinemia induces mild oxidative stress, metabolic changes, and tissue adaptation in rat liver
• Functional consequences of PRODH missense mutations
• Functional specialization in proline biosynthesis of melanoma
• Gamma glutamyl semialdehyde dehydrogenase: simulations on native and mutant forms support the importance of outer shell lysines
• Glutamatergic markers, age, intellectual functioning and psychosis in 22q11 deletion syndrome
• Human aldehyde dehydrogenase genes: alternatively spliced transcriptional variants and their suggested nomenclature
• Hyperprolinemia as a clue in the diagnosis of a patient with psychiatric manifestations
• Hyperprolinemia in Type 2 Glutaric Aciduria and MADD-Like Profiles
• Hyperprolinemia induces DNA, protein and lipid damage in blood of rats: antioxidant protection
• Hyperprolinemia is a risk factor for schizoaffective disorder
• Hyperprolinemia is not associated with childhood onset schizophrenia
• Hyperprolinemia type caused by PRODH gene variation: 2 cases report and literature review
• Hyperprolinemia type I caused by homozygous p.T466M mutation in PRODH
• Hyperprolinemia type Ⅰ caused by PRODH gene variation: 2 cases report and literature review
• Hyperprolinemic larvae of the drosophilid fly, Chymomyza costata, survive cryopreservation in liquid nitrogen
• Identification of delta-1-pyrroline-5-carboxylate derived biomarkers for hyperprolinemia type II
• Identification of PRODH mutations in Korean neonates with type I hyperprolinemia
• Identification of Δ-1-pyrroline-5-carboxylate derived biomarkers for hyperprolinemia type II
• Improving patient tolerability in immunoglobulin treatment: focus on stabilizer effects
• Inborn errors of proline metabolism
• Infantile onset ascending hereditary spastic paralysis
• Influence of proline on rat brain activities of alanine aminotransferase, aspartate aminotransferase and acid phosphatase
• Intellectual Disability Associated With Pyridoxine-Responsive Epilepsies: The Need to Protect Cognitive Development
• Involvement of hyperprolinemia in cognitive and psychiatric features of the 22q11 deletion syndrome
• L-proline determination by molecularly imprinted nanoparticles: A potential nanoscale tool for the diagnosis of metabolic disorders
• Long-term clinical outcome, therapy and mild mitochondrial dysfunction in hyperprolinemia
• Long-term neuropsychiatric follow-up in hyperprolinemia type I
• Long-term proline exposure alters nucleotide catabolism and ectonucleotidase gene expression in zebrafish brain
• Metabolic epilepsy in hyperprolinemia type II due to a novel nonsense ALDH4A1 gene variant
• Mutations in SLC25A22: hyperprolinaemia, vacuolated fibroblasts and presentation with developmental delay
• Myoclonus-Ataxia Syndrome Associated with Hyperprolinemia Type I
• N-(pyrrole-2-carboxyl) glycine a diagnostic marker of hyperprolinaemia type II: mass spectra of trimethylsilyl derivatives
• Neurotoxicity and metabolism of the catecholamine-derived 3,4-dihydroxyphenylacetaldehyde and 3,4-dihydroxyphenylglycolaldehyde: the role of aldehyde dehydrogenase
• New developments in diagnosis and treatment update: Schizophrenia/first episode psychosis in children and adolescents
• Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily
• Noninvasive human metabolome analysis for differential diagnosis of inborn errors of metabolism
• Novel variants in a patient with late-onset hyperprolinemia type II: diagnostic key for status epilepticus and lactic acidosis
• Peculiarities of epileptic syndrome in children with metabolic disorders of nervous system
• Physical exercise reverses cognitive impairment in rats subjected to experimental hyperprolinemia
• Preliminary report of NAD+-dependent amino acid dehydrogenase producing bacteria isolated from soil
• PRODH rs450046 and proline x COMT Val¹⁵⁸ Met interaction effects on intelligence and startle in adults with 22q11 deletion syndrome
• Proline impairs energy metabolism in cerebral cortex of young rats
• Proline oxidase controls proline, glutamate, and glutamine cellular concentrations in a U87 glioblastoma cell line
• Proline promotes decrease in glutamate uptake in slices of cerebral cortex and hippocampus of rats
• Proline reduces brain cytochrome c oxidase: prevention by antioxidants
• Proline-induced changes in acetylcholinesterase activity and gene expression in zebrafish brain: reversal by antipsychotic drugs
• Protective effect of antioxidants on brain oxidative damage caused by proline administration
• Protective effect of green tea extract against proline-induced oxidative damage in the rat kidney
• Psychiatric phenotypes associated with hyperprolinemia: A systematic review
• Pyridoxine and pyridoxalphosphate-dependent epilepsies
• Pyrroline-5-carboxylate reductase 2 (PYCR2) deficiency causes hereditary spastic paraplaegia in late childhood
• Role of antioxidants on Na(+),K (+)-ATPase activity and gene expression in cerebral cortex of hyperprolinemic rats
• SAXS fingerprints of aldehyde dehydrogenase oligomers
• Screening for amino acid metabolic disorders of newborns in Zhejiang province:prevalence, outcome and follow-up
• Selective Screening for Organic Acidurias and Amino Acidopathies in Pakistani Children
• Sensing of hyperprolinemia biomarker and its recognition in biological sample through "turn-on" event by Zn-based metal-organic framework
• Single amino acid polymorphism in aldehyde dehydrogenase gene superfamily
• Status epilepticus and hyperprolinaemia following recurrent gelatine administrations in a patient on peritoneal dialysis
• Structural Biology of Proline Catabolic Enzymes
• Structural determinants of oligomerization of δ(1)-pyrroline-5-carboxylate dehydrogenase: identification of a hexamerization hot spot
• Structure, function, and mechanism of proline utilization A (PutA)
• The 22q11 PRODH/DGCR6 deletion is frequent in hyperprolinemic subjects but is not a strong risk factor for ASD
• The impact of glucose on mitochondria and life span is determined by the integrity of proline catabolism in Caenorhabditis elegans
• The three-dimensional structural basis of type II hyperprolinemia
• Type I Hyperprolinemia - What about the Kidney?
• Type I hyperprolinemia and proline dehydrogenase (PRODH) mutations in four Italian children with epilepsy and mental retardation
• Type I hyperprolinemia: genotype/phenotype correlations
• Unusual Aggregates Formed by the Self-Assembly of Proline, Hydroxyproline, and Lysine
• Update on the aldehyde dehydrogenase gene (ALDH) superfamily
• Update on the treatment of vitamin B6 dependent epilepsies
• Vitamin B6 dependent seizures
• Vitamin B6 related epilepsy during childhood
• Vitamin D insufficiency and schizophrenia risk: evaluation of hyperprolinemia as a mediator of association