Disease: Hereditary nonpolyposis colon cancer
- <em>MLH1</em> Promoter Methylation Could Be the Second Hit in Lynch Syndrome Carcinogenesis
- A 39 kb structural variant causing Lynch Syndrome detected by optical genome mapping and nanopore sequencing
- A Case of Lynch Syndrome-Associated Colorectal Adenocarcinoma in a 19-Year-Old Female Patient
- A Case of Transverse Colon Cancer Associated with Lynch Syndrome with Excellent Response to Pembrolizumab
- A locally advanced colon cancer patient with Muir-Torre syndrome obtains durable response to neoadjuvant and adjuvant immunotherapy
- A mismatched syndrome: A five-year-old girl with very-high-risk leukemia and Lynch syndrome
- A one-stop approach to diagnosing hereditary colorectal cancer in the Chinese population
- A tale of two pathways: Review of immune checkpoint inhibitors in DNA mismatch repair-deficient and microsatellite instability-high endometrial cancers
- Adoption of Universal Testing in Endometrial Cancers for Microsatellite Instability Using Next-Generation Sequencing
- Androgen Receptor Immunohistochemistry is Superior to PRAME for the Differentiation of Sebaceous Carcinoma From Primary Cutaneous Basaloid Mimics
- Apocrine carcinoma with marked sebocyte-like cytological features: A report of two cases
- Association between colorectal cancer, the frequency of Bacteroides fragilis, and the level of mismatch repair genes expression in the biopsy samples of Iranian patients
- Association of a novel frameshift variant and a known deleterious variant in MMR genes with Lynch syndrome in Chinese families
- Attenuated huntingtin gene CAG nucleotide repeat size in individuals with Lynch syndrome
- Balancing the burden and benefits of colonoscopy in Lynch Syndrome
- Beyond Time and Space: Charting Dynamic Evolution of Sporadic Colorectal Cancer
- BRAF(V600E) immunohistochemistry can reliably substitute BRAF molecular testing in the Lynch syndrome screening algorithm in colorectal cancer
- Characteristics and clinical analysis of MLH1 c.463dupC gene mutation in a Lynch syndrome family
- Characterization of mismatch-repair/microsatellite instability-discordant endometrial cancers
- Classification of MLH1 Missense VUS Using Protein Structure-Based Deep Learning-Ramachandran Plot-Molecular Dynamics Simulations Method
- Clinical Outcomes in Sebaceous Carcinoma: A Retrospective Two-Center Cohort Study
- Clinicopathological characteristics, molecular landscape, and biomarker landscape for predicting the efficacy of PD-1/PD-L1 inhibitors in Chinese population with mismatch repair deficient urothelial carcinoma: a real-world study
- Clinicopathological features of colorectal cancer patients under 30 years of age
- Clonal origin and genomic diversity in Lynch syndrome-associated endometrial cancer with multiple synchronous tumors: Identification of the pathogenicity of MLH1 p.L582H
- Co-Occurrence of Germline Genomic Variants and Copy Number Variations in Hereditary Breast and Colorectal Cancer Patients
- Colorectal cancer genetic referral: Are we doing enough?
- Comparison of immediate germline sequencing and multi-step screening for Lynch syndrome detection in high-risk endometrial and colorectal cancer patients
- Comprehensive assessment of mismatch repair and microsatellite instability status in molecular classification of endometrial carcinoma
- De novo germline pathogenic variant in Lynch Syndrome: A rare event or the tip of the iceberg?
- Deficient mismatch repair screening of advanced adenomas in the population screening program for colorectal cancer is not effective
- Detecting microsatellite instability in colorectal cancer using Transformer-based colonoscopy image classification and retrieval
- Development of an Electronic Health Record-Based Clinical Decision Support Tool for Patients With Lynch Syndrome
- Dietary behaviours of individuals with lynch syndrome at high risk of colorectal cancer: Results from the AAS-lynch study
- Efficacy of PD-1 inhibitors for colorectal cancer and polyps in Lynch syndrome patients
- Exercise Training Reduces the Inflammatory Response and Promotes Intestinal Mucosa-Associated Immunity in Lynch Syndrome
- Expanding the Spectrum of Skin Neoplasms in Muir-Torre Syndrome: Beyond Sebaceous Tumours
- Features of colorectal adenomas among young patients with Lynch syndrome according to path_MMR: Results from the PRED-IdF registry
- Functional and phenotypic consequences of an unusual inversion in MSH2
- Genomic Landscape of Lynch Syndrome Colorectal Neoplasia Identifies Shared Mutated Neoantigens for Immunoprevention
- Genotype-phenotype correlations in carriers of the PMS2 founder variant c.1831dup
- Glioma arising in the setting of mismatch repair deficiency-rare or are we missing it?
- Gut microbial signatures are associated with Lynch syndrome (LS) and cancer history in Druze communities in Israel
- Hereditary Nonpolyposis Colon Cancer
- Hormone Receptor-Positive Breast Cancer Sensitive to Pembrolizumab: Evidence of the Pathogenicity of the MLH1 Variant 1835del3
- Identification of people with Lynch syndrome from those presenting with colorectal cancer in England: baseline analysis of the diagnostic pathway
- Immunohistochemistry, Molecular Biology, and Clinical Scoring for the Detection of Muir-Torre Syndrome in Cutaneous Sebaceous Tumors: Which Strategy?
- In vitro study of radiosensitivity in colorectal cancer cell lines associated with Lynch syndrome
- Inherited BRCA1 and RNF43 pathogenic variants in a familial colorectal cancer type X family
- Landscape of somatic mutated genes and inherited susceptibility genes in gynecological cancer
- Less is more: rethinking colorectal cancer resection strategies in Lynch syndrome
- Low prevalence of gastric intestinal metaplasia and Helicobacter pylori on surveillance upper endoscopy in Lynch syndrome
- Lynch syndrome-associated upper tract urothelial carcinoma frequently occurs in patients older than 60 years: an opportunity to revisit urology clinical guidelines
- Metachronous colorectal cancer risk according to Lynch syndrome pathogenic variant after extensive versus partial colectomy in the Netherlands: a retrospective cohort study
- Methylated DNA Markers for Sporadic Colorectal and Endometrial Cancer Are Strongly Associated with Lynch Syndrome Cancers
- Microsatellite Instability Is Insufficiently Used as a Biomarker for Lynch Syndrome Testing in Clinical Practice
- Mismatch repair deficiency in multifocal gastric epithelial neoplasia and non-dysplastic glands: Harbinger of Lynch syndrome in an autoimmune gastritis patient
- MLH1 Promotor Hypermethylation in Colorectal and Endometrial Carcinomas from Patients with Lynch Syndrome
- Modifiable Risk Factors and Risk of Colorectal and Endometrial Cancers in Lynch Syndrome: A Systematic Review and Meta-Analysis
- Molecular analysis of cancer genomes in children with Lynch syndrome: Exploring causal associations
- Molecular characterization as new driver in prognostic signatures and therapeutic strategies for endometrial cancer
- Mosaic Muir Torre Syndrome: Keratoacanthoma as a Piece of the Puzzle
- MTHFR C677T and A1298C polymorphism's effect on risk of colorectal cancer in Lynch syndrome
- Muir-Torre Syndrome
- Muir-Torre syndrome and recent updates on screening guidelines: The link between colorectal tumors and sebaceous adenomas in unusual locations
- Muir-Torre Syndrome with Novel Mutation in the MSH2 Gene
- Neoplasia risk in patients with Lynch syndrome treated with immune checkpoint blockade
- New Insights into Lynch Syndrome: A Narrative Review
- Novel MSH2 and TSC2 variants in a Chinese family with Lynch syndrome and their synergistic impact in urothelial carcinoma
- PGT-M, a Useful Tool to Manage the Lynch Syndrome Transmission
- PREMM5 distinguishes sporadic from Lynch syndrome-associated MMR-deficient/MSI-high colorectal cancer
- Prevalence and characteristics of patients with upper urinary tract urothelial carcinoma having potential Lynch syndrome identified by immunohistochemical universal screening and Amsterdam criteria II
- Preventive strategies in familial and hereditary colorectal cancer
- Providing Opportunities for Close Examination of Lynch Syndrome after Microsatellite Instability Testing in a Hospital Setting
- Province-Wide Ascertainment of Lynch Syndrome in Manitoba
- Rare germline mutation and MSH2-&MSH6 + expression in a double primary carcinoma of colorectal carcinoma and endometrial carcinoma: a case report
- Rare germline mutation and MSH2-&MSH6 + expression in a double primary carcinoma of colorectal carcinoma and endometrial carcinoma: a case report
- Rare single-nucleotide variants of MLH1 and MSH2 genes in patients with Lynch syndrome
- Rechallenge With Switching Immune Checkpoint Inhibitors Following Autoimmune Myocarditis in a Patient With Lynch Syndrome
- Recurrent colon cancer in a patient with Muir-Torre syndrome: a case report
- Risk for Hereditary Neoplastic Syndromes in Women with Mismatch Repair-Proficient Endometrial Cancer
- Risk of metachronous colorectal cancer after colectomy for first colon cancer in Lynch syndrome: multicenter retrospective study in Japan
- Risk-stratified faecal immunochemical testing (FIT) for urgent colonoscopy in Lynch syndrome during the COVID-19 pandemic
- Sarcoma in patients with Lynch syndrome and response to immunotherapy
- Screening and surveillance for hereditary colorectal cancer
- Sebaceous carcinoma in a 54-year-old Black African man after cancer chemotherapy: a case report
- Small intestinal adenocarcinoma accompanied by lynch syndrome: A case report
- Sporadic Prostate Cancer in a Patient With Lynch Syndrome
- Sustained Disease Control in Immune Checkpoint Blockade Responders with Microsatellite Instability-high Colorectal Cancer after Treatment Termination
- Synchronous Gastric and Colonic Adenocarcinoma: A Case Report With its Molecular Implications
- Testing for deficient mismatch repair and microsatellite instability : A focused update
- The Progress of Colorectal Polyposis Syndrome in Chinese Population
- The Role of the Transforming Growth Factor-β Signaling Pathway in Gastrointestinal Cancers
- The structure of pathogenic germline variants in colorectal cancer in Moscow patients
- The two-in-one hit model of the short-cut carcinogenesis of colorectal carcinomas in MLH1-associated Lynch syndrome
- Tracheal Chondrosarcoma-A Novel Presentation of Lynch Syndrome
- Tumor analysis of MMR genes in Lynch-like syndrome: Challenges associated with results interpretation
- Turcot Syndrome
- Two Cases Suspected of Lynch Syndrome Caused by Juvenile Rectal Cancer
- Universal testing of cutaneous sebaceous carcinoma: a missed opportunity in Lynch syndrome detection
- Use of endoscopic submucosal dissection in a patient with synchronous and metachronous gastric cancers secondary to MSH2-related Lynch syndrome