• <em>Aspergillus fumigatus</em> Challenged by Human Dendritic Cells: Metabolic and Regulatory Pathway Responses Testify a Tight Battle
• <em>De novo</em> p.Glu61Ter mutation in GCH1 in a Moroccan patient with dopa-responsive dystonia: a case report
• A key role for tetrahydrobiopterin-dependent endothelial NOS regulation in resistance arteries: studies in endothelial cell tetrahydrobiopterin-deficient mice
• A Novel GCH1 Mutation in An Indian Child with GTP Cyclohydrolase Deficiency
• A novel GTPCH deficiency mouse model exhibiting tetrahydrobiopterin-related metabolic disturbance and infancy-onset motor impairments
• A novel missense mutation of the GTP cyclohydrolase 1 gene in a Taiwanese family with dopa-responsive dystonia: A case report
• A novel role for endothelial tetrahydrobiopterin in mitochondrial redox balance
• An unusual presentation of tyrosine hydroxylase deficiency
• Autosomal recessive GTPCH 1 deficiency: the importance of the analysis of neurotransmitters in cerebrospinal fluid
• Bacillus subtilis FolE is sustained by the ZagA zinc metallochaperone and the alarmone ZTP under conditions of zinc deficiency
• BH(4) deficiency identified in a neonatal screening program for hyperphenylalaninemia
• BH₄ deficiency identified in a neonatal screening program for hyperphenylalaninemia
• Catecholamines and Parkinson's disease: tyrosine hydroxylase (TH) over tetrahydrobiopterin (BH4) and GTP cyclohydrolase I (GCH1) to cytokines, neuromelanin, and gene therapy: a historical overview
• Child Neurology: A young child with an undiagnosed case of dystonia responsive to l-dopa
• Comment on "Mild dopa-responsive dystonia in heterozygous tyrosine hydroxylase mutation carrier: Evidence of symptomatic enzyme deficiency?"
• Common and rare GCH1 variants are associated with Parkinson's disease
• Comparative Analysis of Sporulating and Spore-Deficient Strains of Agrocybe salicacola Based on the Transcriptome Sequences
• Crucial neuroprotective roles of the metabolite BH4 in dopaminergic neurons
• Current Understanding of the Mechanisms Underlying Immune Evasion From PD-1/PD-L1 Immune Checkpoint Blockade in Head and Neck Cancer
• De novo tetrahydrobiopterin biosynthesis is impaired in the inflammed striatum of parkin^(-/-) mice
• Dexamethasone, tetrahydrobiopterin and uncoupling of endothelial nitric oxide synthase
• Diagnosing dopamine-responsive dystonias
• Disorders of purine biosynthesis metabolism
• Dopa-responsive dystonia in Chinese patients: Including a novel heterozygous mutation in the GCH1 gene with an intermediate phenotype and one case of prenatal diagnosis
• Dopa-responsive dystonia--clinical and genetic heterogeneity
• Early-onset autosomal dominant GTP-cyclohydrolase I deficiency: Diagnostic delay and residual motor signs
• Endothelial cell tetrahydrobiopterin deficiency attenuates LPS-induced vascular dysfunction and hypotension
• Endothelial Cell Tetrahydrobiopterin Modulates Sensitivity to Ang (Angiotensin) II-Induced Vascular Remodeling, Blood Pressure, and Abdominal Aortic Aneurysm
• Endothelial cell vasodilator dysfunction mediates progressive pregnancy-induced hypertension in endothelial cell tetrahydrobiopterin deficient mice
• Endothelial cell-derived tetrahydrobiopterin prevents aortic valve calcification
• Endothelial cell-specific roles for tetrahydrobiopterin in myocardial function, cardiac hypertrophy, and response to myocardial ischemia-reperfusion injury
• Folic Acid Production by Engineered Ashbya gossypii
• Four Years of Diagnostic Challenges with Tetrahydrobiopterin Deficiencies in Iranian Patients
• GCH-1 genetic variant may cause Parkinsonism by unmasking the subclinical nigral pathology
• GCH1 Deficiency Activates Brain Innate Immune Response and Impairs Tyrosine Hydroxylase Homeostasis
• GCH1 mutations are common in Serbian patients with dystonia-parkinsonism: Challenging previously reported prevalence rates of DOPA-responsive dystonia
• GCH1 mutations in hereditary spastic paraplegia
• GCH1: GTP cyclohydroxylase1: Role in neurodegenerative diseases
• Generation of an iPSC line from a patient with GTP cyclohydrolase 1 (GCH1) deficiency: HDMC0061i-GCH1
• Genetic and physiological regulation of folate in pak choi (Brassica rapa subsp. Chinensis) germplasm
• Genetic landscape of Segawa disease in Spain. Long-term treatment outcomes
• GTP Cyclohydrolase Drives Breast Cancer Development and Promotes EMT in an Enzyme-Independent Manner
• GTP cyclohydroxylase1 (GCH1): Role in neurodegenerative diseases
• GTP-cyclohydrolase deficiency induced peripheral and deep microcirculation dysfunction with age
• GTP-Cyclohydrolase I deficiency presenting as malignant hyperphenylalaninemia, recurrent hyperthermia and progressive neurological dysfunction in a South Asian child - a case report
• Human tyrosine hydroxylase in Parkinson's disease and in related disorders
• Hyperoxia depletes (6R)-5,6,7,8-tetrahydrobiopterin levels in the neonatal retina: implications for nitric oxide synthase function in retinopathy
• Increased Reactive Oxygen Species Generation Contributes to the Atherogenic Activity of the B2 Bradykinin Receptor
• Inherited dystonias: clinical features and molecular pathways
• Inhibition of Aberrant MicroRNA-133a Expression in Endothelial Cells by Statin Prevents Endothelial Dysfunction by Targeting GTP Cyclohydrolase 1 in Vivo
• Intestinal microbiota as a tetrahydrobiopterin exogenous source in hph-1 mice
• Ionizing radiation induces BH(4) deficiency by downregulating GTP-cyclohydrolase 1, a novel target for preventing and treating radiation enteritis
• Ionizing radiation induces BH₄ deficiency by downregulating GTP-cyclohydrolase 1, a novel target for preventing and treating radiation enteritis
• Isolation and In vitro Culture of Bone Marrow-Derived Macrophages for the Study of NO-Redox Biology
• Marginal BH4 deficiencies, iNOS, and self-perpetuating oxidative stress in post-acute sequelae of Covid-19
• Mast cell tetrahydrobiopterin contributes to itch in mice
• Mast cell-derived BH4 is a critical mediator of postoperative pain
• Mechanisms underlying the efficacy and limitation of dopa and tetrahydrobiopterin therapies for the deficiency of GTP cyclohydrolase 1 revealed in a novel mouse model
• Metabolic engineering of folate and its precursors in Mexican common bean (Phaseolus vulgaris L.)
• Metabonomic analysis of potential biomarkers and drug targets involved in diabetic nephropathy mice
• Molecular and metabolic bases of tetrahydrobiopterin (BH(4)) deficiencies
• Molecular and metabolic bases of tetrahydrobiopterin (BH₄) deficiencies
• Molecular genetics of phenylketonuria and tetrahydrobiopterin deficiency in Jordan
• Molecular genetics of tetrahydrobiopterin deficiency in Chinese patients
• Neurometabolic causes of dystonia: Sepiapterin reductase-deficient dopamine- and serotonin-responsive dystonia-plus syndrome
• Neuropsychiatric and sleep study in autosomal dominant dopa-responsive dystonia
• Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages through TCA Cycle Regulation and Itaconate Accumulation
• Nitrosative stress induced by homocysteine thiolactone drives vascular cognitive impairments via GTP cyclohydrolase 1 S-nitrosylation in vivo
• Non-motor symptoms and quality of life in dopa-responsive dystonia patients
• Non-motor symptoms in genetically defined dystonia: Homogenous groups require systematic assessment
• Nucleoside Diphosphate Kinase Escalates A-to-C Mutations in MutT-Deficient Strains of Escherichia coli
• Nucleotide Variants of the BH4 Biosynthesis Pathway Gene GCH1 and the Risk of Orofacial Clefts
• Older-onset levodopa-responsive parkinsonism with normal DAT-SPECT and pterin hypometabolism
• Oxidative Stress, GTPCH1, and Endothelial Nitric Oxide Synthase Uncoupling in Hypertension
• Personalized Medicine to Improve Treatment of Dopa-Responsive Dystonia-A Focus on Tyrosine Hydroxylase Deficiency
• Recessive GCH1 Deficiency Causing DOPA-Responsive Dystonia Diagnosed by Reported Negative Exome
• Regulation of mycobacterial infection by macrophage Gch1 and tetrahydrobiopterin
• Relationship between guanosine triphosphate pathway and tetrahydrobiopterin in gestational diabetes mellitus
• Reply to: Neurometabolic causes of dystonia: Sepiapterin reductase-deficient dopamine- and serotonin-responsive dystonia-plus syndrome
• Reversal of Pulmonary Hypertension in a Human-Like Model: Therapeutic Targeting of Endothelial DHFR
• Roles for endothelial cell and macrophage Gch1 and tetrahydrobiopterin in atherosclerosis progression
• Serotonergic system in vivo with [(11)C]DASB PET scans in GTP-cyclohydrolase deficient dopa-responsive dystonia patients
• Serotonergic system in vivo with [¹¹C]DASB PET scans in GTP-cyclohydrolase deficient dopa-responsive dystonia patients
• Suppression of GCH1 Sensitizes Ovarian Cancer and Breast Cancer to PARP Inhibitor
• Targeting feed-forward signaling of TGFβ/NOX4/DHFR/eNOS uncoupling/TGFβ axis with anti-TGFβ and folic acid attenuates formation of aortic aneurysms: Novel mechanisms and therapeutics
• Tetrahydrobiopterin (BH₄ ): Targeting endothelial nitric oxide synthase as a potential therapy for pulmonary hypertension
• Tetrahydrobiopterin deficiencies: Lesson from clinical experience
• Tetrahydrobiopterin in antenatal brain hypoxia-ischemia-induced motor impairments and cerebral palsy
• Tetrahydrobiopterin metabolism attenuates ROS generation and radiosensitivity through LDHA S-nitrosylation: novel insight into radiogenic lung injury
• Tetrahydrobiopterin modulates ubiquitin conjugation to UBC13/UBE2N and proteasome activity by S-nitrosation
• Tetrahydrobiopterin treatment reduces brain L-Phe but only partially improves serotonin in hyperphenylalaninemic ENU1/2 mice
• The Inhibitory Effect of Ojeoksan on Early and Advanced Atherosclerosis
• The Interactions Between Kynurenine, Folate, Methionine and Pteridine Pathways in Obesity
• The International Working Group on Neurotransmitter related Disorders (iNTD): A worldwide research project focused on primary and secondary neurotransmitter disorders
• The treatment and clinical follow-up outcome in Iranian patients with tetrahydrobiopterin deficiency
• Three-Dimensional Gait Analysis as a Biomarker for GTP Cyclohydrolase 1-Deficient Dopa-Responsive Dystonia
• Time estimation and arousal responses in dopa-responsive dystonia
• Transcranial sonography in dopa-responsive dystonia
• Tyrosine hydroxylase (TH), its cofactor tetrahydrobiopterin (BH4), other catecholamine-related enzymes, and their human genes in relation to the drug and gene therapies of Parkinson's disease (PD): historical overview and future prospects
• Zinc supplementation protects against diabetic endothelial dysfunction via GTP cyclohydrolase 1 restoration