Disease: Familial platelet disorder with associated myeloid malignancy
- <em>RUNX1</em> Familial Platelet Disorder with Associated Myeloid Malignancies
- A <em>de novo</em> germline <em>RUNX1</em> variant preceding development of concurrent T-lymphoblastic leukemia and myelodysplastic syndrome
- A novel RUNX1 exon 3 - 7 deletion causing a familial platelet disorder
- A RUNX1-FPDMM rhesus macaque model reproduces the human phenotype and predicts challenges to curative gene therapies
- A Systematic Review of the Role of Runt-Related Transcription Factor 1 (RUNX1) in the Pathogenesis of Hematological Malignancies in Patients With Inherited Bone Marrow Failure Syndromes
- Altered platelet-megakaryocyte endocytosis and trafficking of albumin and fibrinogen in RUNX1 haplodeficiency
- Bone Marrow Morphology Associated With Germline <em>RUNX1</em> Mutations in Patients With Familial Platelet Disorder With Associated Myeloid Malignancy
- Clinical Relevance of RUNX1 and CBFB Alterations in Acute Myeloid Leukemia and Other Hematological Disorders
- Correction to: Functional classification of RUNX1 variants in familial platelet disorder with associated myeloid malignancies
- Efficacy of novel agents against cellular models of familial platelet disorder with myeloid malignancy (FPD-MM)
- Familial platelet disorder due to germline exonic deletions in <em>RUNX1</em>: a diagnostic challenge with distinct alterations of the transcript isoform equilibrium
- Familial predisposition of myeloid malignancies: biological and clinical significance of recurrent germ line mutations
- FLI1 is associated with regulation of DNA methylation and megakaryocytic differentiation in FPDMM caused by a RUNX1 transactivation domain mutation
- Gene of the issue: RUNX1 mutations and inherited bleeding
- Genomic Landscape of Patients with Germline <em>RUNX1</em> Variants and Familial Platelet Disorder with Myeloid Malignancy
- Genomic Landscape of Patients with Germline RUNX1 Variants and Familial Platelet Disorder with Myeloid Malignancy
- Genomic landscape of patients with germline RUNX1 variants and familial platelet disorder with myeloid malignancy
- GENYOi005-A: An induced pluripotent stem cells (iPSCs) line generated from a patient with Familial Platelet Disorder with associated Myeloid Malignancy (FPDMM) carrying a p.Thr196Ala variant
- Germline <em>RUNX1</em> variants in paediatric patients in a French specialised centre
- Haematological spectrum and genotype-phenotype correlations in nine unrelated families with RUNX1 mutations from the French network on inherited platelet disorders
- Hematopoietic Cell Autonomous Disruption of Hematopoiesis in a Germline Loss-of-function Mouse Model of <em>RUNX1</em>-FPD
- Myelodysplastic syndromes and acute leukemia with genetic predispositions: a new challenge for hematologists
- Myeloid neoplasms with germ line RUNX1 mutation
- Natural history study of patients with familial platelet disorder with associated myeloid malignancy
- Natural History Study of Patients with Familial Platelet Disorder with Myeloid Malignancy
- Needle in a haystack or elephant in the room? Identifying germline predisposition syndromes in the setting of a new myeloid malignancy diagnosis
- NIH natural history study of FPDMM patients
- Prevalence and clinical expression of germ line predisposition to myeloid neoplasms in adults with marrow hypocellularity
- RUNX1 deficiency (familial platelet disorder with predisposition to myeloid leukemia, FPDMM)
- RUNX1 Familial Platelet Disorder with Associated Myeloid Malignancies
- RUNX1 is required in granulocyte-monocyte progenitors to attenuate inflammatory cytokine production by neutrophils
- RUNX1 is required in granulocyte-monocyte progenitors to attenuate inflammatory cytokine production by neutrophils
- RUNX1-deficient human megakaryocytes demonstrate thrombopoietic and platelet half-life and functional defects
- Somatic Exonic Deletions in RUNX1 Constitutes a Novel Recurrent Genomic Abnormality in Acute Myeloid Leukemia
- Spectrum of clinical and genetic features of patients with inherited platelet disorder with suspected predisposition to hematological malignancies: a nationwide survey in Japan
- The clinical phenotype of germline RUNX1 mutations in relation to the accompanying somatic variants and RUNX1 isoform expression
- Unrelated hematopoietic stem cell transplantation for familial platelet disorder/acute myeloid leukemia with germline RUNX1 mutations
- Validation and clinical application of transactivation assays for RUNX1 variant classification
- WAS-Related Disorders