• 47, XY, +der(Y),t(X;Y)(p21.1;p11.2): a unique case of XY sex reversal
• A de novo 1.58 Mb deletion, including MAP2K6 and mapping 1.28 Mb upstream to SOX9, identified in a patient with Pierre Robin sequence and osteopenia with multiple fractures
• A de novo mutation of DAX1 in a boy with congenital adrenal hypoplasia without hypogonadotropic hypogonadism
• A new DAX-1 mutation in a family with a case of neonatal adrenal insufficiency and a sibling with adrenal hypoplasia and sudden death at 3 years of age
• A Novel Look at Dosage-Sensitive Sex Locus Xp21.2 in a Case of 46,XY Partial Gonadal Dysgenesis without <em>NR0B1</em> Duplication
• A Novel Muscle Atrophy Mechanism: Myocyte Degeneration Due to Intracellular Iron Deprivation
• A phenotypic spectrum of sexual development in Dax1 (Nr0b1)-deficient mice: consequence of the C57BL/6J strain on sex determination
• Acid ceramidase (ASAH1) is a global regulator of steroidogenic capacity and adrenocortical gene expression
• Adrenal hypoplasia congenita presenting as congenital adrenal hyperplasia
• Adult‑onset X‑linked adrenal hypoplasia congenita caused by a novel mutation in DAX1/NR0B1: A case report and literature review
• Aldosterone-producing adenoma formation in the adrenal cortex involves expression of stem/progenitor cell markers
• An amino-terminal DAX1 (NROB1) missense mutation associated with isolated mineralocorticoid deficiency
• Androgens inhibit aromatase expression through DAX-1: insights into the molecular link between hormone balance and Leydig cancer development
• Anomalies in Human Sex Determination: Usefulness of a Combined Cytogenetic Approach to Characterize an Additional Case with Xp Functional Disomy Associated with 46,XY Gonadal Dysgenesis
• Are human male patients with DAX1/NR0B1 mutations infertile?
• cAMP-independent signaling regulates steroidogenesis in mouse Leydig cells in the absence of StAR phosphorylation
• CBP/p300-interacting transactivator, with Glu/Asp-rich C-terminal domain, 2, and pre-B-cell leukemia transcription factor 1 in human adrenal development and disease
• CCAAT/enhancer-binding protein β is involved in the breed-dependent transcriptional regulation of 3β-hydroxysteroid dehydrogenase/Δ(5)-Δ(4)-isomerase in adrenal gland of preweaning piglets
• Central precocious puberty in a patient with X-linked adrenal hypoplasia congenita and Xp21 contiguous gene deletion syndrome
• Characteristic induction of steroidogenic factor 1 (SF-1) and DAX-1 and enhanced expression of glucocorticoid synthesis-related genes in adrenals from spontaneously hypertensive rats
• Clinical and molecular genetic analysis of a Chinese family with congenital X-linked adrenal hypoplasia caused by novel mutation 1268delA in the DAX-1 gene
• DAX-1 (dosage-sensitive sex reversal-adrenal hypoplasia congenita critical region on the X-chromosome, gene 1) selectively inhibits transactivation but not transrepression mediated by the glucocorticoid receptor in a LXXLL-dependent manner
• DAX-1 acts as a novel corepressor of orphan nuclear receptor HNF4alpha and negatively regulates gluconeogenic enzyme gene expression
• DAX-1 and DAX-1A expression in human testicular tissues with primary spermatogenic failure
• DAX-1 inhibits hepatocellular carcinoma proliferation by inhibiting β-catenin transcriptional activity
• DAX-1A (NR0B1A) expression levels are extremely low compared to DAX-1 (NR0B1) in human steroidogenic tissues
• DAX1 regulatory networks unveil conserved and potentially new functions
• DAX1 suppresses FXR transactivity as a novel co-repressor
• Delayed-onset adrenal hypoplasia congenita and hypogonadotropic hypogonadism caused by a novel mutation in <em>DAX1</em>
• Developmental Programming: Prenatal Testosterone Excess on Ovarian SF1/DAX1/FOXO3
• Disorders of adrenal development
• Distinct nuclear receptor expression in stroma adjacent to breast tumors
• Distinct repressive properties of the mammalian and fish orphan nuclear receptors SHP and DAX-1
• DMRT1/Dmrt1, the sex determining or sex differentiating gene in Vertebrata
• Dosage-sensitive sex reversal adrenal hypoplasia congenita critical region on the X chromosome, gene 1 (DAX1) (NR0B1) and small heterodimer partner (SHP) (NR0B2) form homodimers individually, as well as DAX1-SHP heterodimers
• Duplication of dosage sensitive sex reversal area in a 46, XY patient with normal sex determining region of Y causing complete sex reversal
• Dynamic pituitary-adrenal interactions in response to cardiac surgery
• Effect of sex inversion in embryos of domestic chicken (Gallu gallus domesticus) by influence of letrozole and tamoxifen
• Effects of apigenin on steroidogenesis and steroidogenic acute regulatory gene expression in mouse Leydig cells
• Evidence of adrenal failure in aging Dax1-deficient mice
• Evolution of the gene network underlying gonadogenesis in turtles with temperature-dependent and genotypic sex determination
• Excess DAX1 leads to XY ovotesticular disorder of sex development (DSD) in mice by inhibiting steroidogenic factor-1 (SF1) activation of the testis enhancer of SRY-box-9 (Sox9)
• Expression of aldosterone synthase and adrenocorticotropic hormone receptor in adrenal incidentalomas from normotensive and hypertensive patients: Distinguishing subclinical or atypical primary aldosteronism from adrenal incidentaloma
• Expression of selected genes involved in steroidogenesis in the course of enucleation-induced rat adrenal regeneration
• Female-to-male sex reversal associated with unique Xp21.2 deletion disrupting genomic regulatory architecture of the dosage-sensitive sex reversal region
• Four Japanese patients with adrenal hypoplasia congenita and hypogonadotropic hypogonadism caused by DAX-1 gene mutations: mutant DAX-1 failed to repress steroidogenic acute regulatory protein (StAR) and luteinizing hormone beta-subunit gene promoter acti
• Gene dosage of DAX-1, determining in sexual differentiation: duplication of DAX-1 in two sisters with gonadal dysgenesis
• Gene expression patterns in juvenile American alligators (Alligator mississippiensis) exposed to environmental contaminants
• GnRH pulse frequency differentially regulates steroidogenic factor 1 (SF1), dosage-sensitive sex reversal-AHC critical region on the X chromosome gene 1 (DAX1), and serum response factor (SRF): potential mechanism for GnRH pulse frequency regulation of LH
• Gonadotropin-releasing hormone and gonadal steroids regulate transcription factor mRNA expression in primary pituitary and immortalized gonadotrope cells
• Heat stress upregulates aromatases expression through nuclear DAX-1 deficiency in R2C Leydig tumor cells
• Hepatocyte DAX1 Deletion Exacerbates Inflammatory Liver Injury by Inducing the Recruitment of CD4⁺ and CD8⁺ T Cells through NF-κB p65 Signaling Pathway in Mice
• Hepatocyte-Specific Deficiency of DAX-1 Protects Mice from Acetaminophen-Induced Hepatotoxicity by Activating NRF2 Signaling
• Human fetal adrenal cells retain age-related stem- and endocrine-differentiation potential in culture
• Hypogonadotropic hypogonadism in subjects with DAX1 mutations
• Identification and Functional Evaluation of Alternative Splice Variants of Dax1 in Mouse Embryonic Stem Cells
• Identification and involvement of DAX1 gene in spermatogenesis of boring giant clam Tridacna crocea
• In ovo injection of betaine promotes adrenal steroidogenesis in pre-hatched chicken fetuses
• In vivo inhibition of steroidogenic acute regulatory protein expression by dexamethasone parallels induction of the negative transcription factor DAX-1
• Induced Pluripotent Stem Cells from a Marsupial, the Tasmanian Devil (Sarcophilus harrisii): Insight into the Evolution of Mammalian Pluripotency
• Inhibition of GLI Transcriptional Activity and Prostate Cancer Cell Growth and Proliferation by DAX1
• Insulin directly regulates steroidogenesis via induction of the orphan nuclear receptor DAX-1 in testicular Leydig cells
• Interleukin-6 inhibits adrenal androgen release from bovine adrenal zona reticularis cells by inhibiting the expression of steroidogenic proteins
• Investigation of Flavonoid Scaffolds as DAX1 Inhibitors against Ewing Sarcoma through Pharmacoinformatic and Dynamic Simulation Studies
• Involvement of the thromboxane A2 receptor in the regulation of steroidogenic acute regulatory gene expression in murine Leydig cells
• Late-onset vanishing testis-like syndrome in a 38,XX/38,XY agonadic pig (Sus scrofa)
• Liver receptor homolog-1 and steroidogenic factor-1 have similar actions on rat granulosa cell steroidogenesis
• LXXLL motifs and AF-2 domain mediate SHP (NR0B2) homodimerization and DAX1 (NR0B1)-DAX1A heterodimerization
• Male-to-female sex reversal associated with an approximately 250 kb deletion upstream of NR0B1 (DAX1)
• microRNA-181 promotes prostate cancer cell proliferation by regulating DAX-1 expression
• MicroRNA-561 promotes acetaminophen-induced hepatotoxicity in HepG2 cells and primary human hepatocytes through downregulation of the nuclear receptor corepressor dosage-sensitive sex-reversal adrenal hypoplasia congenital critical region on the X chromos
• Molecular characterisation of a der(Y)t(Xp;Yp) with Xp functional disomy and sex reversal
• New perspectives on PPAR, VDR and FXRα as new actors in testicular pathophysiology
• Next-Generation Sequencing Identifies Different Genetic Defects in 2 Patients with Primary Adrenal Insufficiency and Gonadotropin-Independent Precocious Puberty
• Non-conventional Genetic Basis of Congenital Adrenal Hypoplasia in South Asia
• Novel frameshift mutation of the NR0B1(DAX1) in two tall adult brothers
• Novel mutations and spectrum of the disease of NR0B1 (DAX1)-related adrenal insufficiency in Indian children
• Novel mutations of DAX1 (NR0B1) in two Chinese families with X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism
• Novel non-stop variant of the <em>NR0B1</em> gene in two siblings with adrenal hypoplasia congenita
• Nuclear receptor DAX1 in human prostate cancer: a novel independent biological modulator
• Orphan nuclear receptor DAX-1 acts as a novel corepressor of liver X receptor alpha and inhibits hepatic lipogenesis
• Orphan nuclear receptors as drug targets for the treatment of prostate and breast cancers
• Pre-B-cell transcription factor 1 and steroidogenic factor 1 synergistically regulate adrenocortical growth and steroidogenesis
• Presence of 21-Hydroxylase Antibodies in a Boy with X-Linked Adrenal Hypoplasia Congenita
• Regulation of Leydig cell steroidogenesis by extracellular signal-regulated kinase 1/2: role of protein kinase A and protein kinase C signaling
• Role of dosage-sensitive sex reversal, adrenal hypoplasia congenita, critical region on the X chromosome, gene 1 in protein kinase A- and protein kinase C-mediated regulation of the steroidogenic acute regulatory protein expression in mouse Leydig tumor c
• Role of SF-1 and DAX-1 during differentiation of P19 cells by retinoic acid
• Seven novel DAX1 mutations with loss of function identified in Chinese patients with congenital adrenal hypoplasia
• Sex reversal in C57BL/6J XY mice caused by increased expression of ovarian genes and insufficient activation of the testis determining pathway
• Sibling cases of Addison's disease caused by DAX-1 gene mutations
• SOX9 chromatin folding domains correlate with its real and putative distant cis-regulatory elements
• Steroidogenesis in the skin: implications for local immune functions
• Targeting 17β-estradiol biosynthesis in neural stem cells improves stroke outcome
• Temperature sex reversal implies sex gene dosage in a reptile
• The Expression Pattern of Insulin-Like Growth Factor Subtype 3 (igf3) in the Orange-Spotted Grouper <em>Epinephelus coioides</em> and Its Function on Ovary Maturation
• The signaling phospholipid PIP3 creates a new interaction surface on the nuclear receptor SF-1
• Three cases of congenital adrenal hypoplasia with novel mutations in the (NROB1) DAX-1 gene
• TNF-α-mediated suppression of Leydig cell steroidogenesis involves DAX-1
• X-linked congenital adrenal hypoplasia associated with hypospadias in an Egyptian baby: a case report
• X-linked congenital adrenal hypoplasia with hypogonadotropic hypogonadism caused by an inversion disrupting a conserved noncoding element upstream of the NR0B1 (DAX1) gene