Disease: Deficiency of the Interleukin-1 Receptor Antagonist
- A case report of a novel compound heterozygous mutation in a Brazilian patient with deficiency of Interleukin-1 receptor antagonist (DIRA)
- A case report of mevalonate kinase deficiency in a 14-month-old female with fevers and lower extremity weakness
- A novel mutation of interleukin-1 receptor antagonist (IL1RN) in a DIRA patient from Turkey: Diagnosis and treatment
- Accuracy of generative artificial intelligence models in differential diagnoses of familial Mediterranean fever and deficiency of Interleukin-1 receptor antagonist
- Advances in clinical outcomes: What we have learned during the COVID-19 pandemic
- Analysis of Anakinra Therapy for the Deficiency of Interleukin-1 Receptor Antagonist through Clinical Evidence
- Autotaxin inhibition attenuates the aortic valve calcification by suppressing inflammation-driven fibro-calcific remodeling of valvular interstitial cells
- Blocking of interleukin-1 suppresses angiotensin II-induced renal injury
- Case report: Novel compound heterozygous IL1RN mutations as the likely cause of a lethal form of deficiency of interleukin-1 receptor antagonist
- Clinical advances in biological therapy for generalized pustular psoriasis: a review
- Consensus protocols for the diagnosis and management of the hereditary autoinflammatory syndromes CAPS, TRAPS and MKD/HIDS: a German PRO-KIND initiative
- Coupling Between Interleukin-1R1 and Necrosome Complex Involves in Hemin-Induced Neuronal Necroptosis After Intracranial Hemorrhage
- Deficiency of Interleukin-1 Receptor Antagonist: A Case with Late Onset Severe Inflammatory Arthritis, Nail Psoriasis with Onychomycosis and Well Responsive to Adalimumab Therapy
- Deficiency of Interleukin-1 Receptor Antagonist: New Genetic Autoinflammatory Disease as a Diagnostic Challenge for Pediatricians
- Dermal fibroblasts are the key sensors of aseptic skin inflammation through interleukin 1 release by lesioned keratinocytes
- Diet-Induced Obese Mice and Leptin-Deficient <em>Lep<sup>ob/ob</sup></em> Mice Exhibit Increased Circulating GIP Levels Produced by Different Mechanisms
- Diet-Induced Obese Mice and Leptin-Deficient Lep(ob/ob) Mice Exhibit Increased Circulating GIP Levels Produced by Different Mechanisms
- Distinct anti-inflammatory properties of alpha1-antitrypsin and corticosteroids reveal unique underlying mechanisms of action
- Ectonucleotidase tri(di)phosphohydrolase-1 (ENTPD-1) disrupts inflammasome/interleukin 1β-driven venous thrombosis
- Effect of Baihe Gujin decoction combined with Shengmai powder on the expression of IL-1β and IL-1Ra in peripheral blood CD14+ monocytes from patients with pulmonary tuberculosis
- Efficacy of Anakinra Treatment in two Moroccan Patients With Mevalonate Kinase Deficiency
- Enterotoxigenic <em>Escherichia coli</em> Enterotoxins Regulate Epithelial to Immune Relay of IL-33 and IL-1Ra Cytokines
- Exosomes Derived from Adipose Tissue-Derived Mesenchymal Stromal Cells Prevent Medication-Related Osteonecrosis of the Jaw through IL-1RA
- Exploring possible relationships between 25(OH)D deficiency and variables related to inflammation, endothelial function, and enzymatic antioxidants in adolescent athletes: a prospective study
- Extinguishing Febrile Infection-Related Epilepsy Syndrome: Pipe Dream or Reality?
- Familial Mediterranean Fever
- Functional deficiency in endogenous interleukin-1 receptor antagonist in patients with febrile infection-related epilepsy syndrome
- Genetic diagnosis of autoinflammatory disease patients using clinical exome sequencing
- Germline HAVCR2/TIM-3 Checkpoint Inhibitor Receptor Deficiency in Recurrent Autoinflammatory Myocarditis
- Homozygous IL1RN Mutation in Siblings with Deficiency of Interleukin-1 Receptor Antagonist (DIRA)
- IL-1 Antagonism in Men With Metabolic Syndrome and Low Testosterone: A Randomized Clinical Trial
- IL-1 Inhibition and Function of the HDL-Containing Fraction of Plasma in Patients with Stages 3 to 5 CKD
- IL-1R1 blockade attenuates liver injury through inhibiting the recruitment of myeloid-derived suppressor cells in sepsis
- IL-1Ra deficiency accelerates intervertebral disc degeneration in C57BL6J mice
- IL-1RA is part of the inflammasome-regulated immune response in bladder epithelial cells and influences colonization of uropathogenic E. coli
- IL-1β Damages Fibrocartilage and Upregulates MMP-13 Expression in Fibrochondrocytes in the Condyle of the Temporomandibular Joint
- IL-1β is not critical to chronic heart dysfunction in mice with Chagas disease
- IL-1β-driven osteoclastogenic Tregs accelerate bone erosion in arthritis
- IL-25 exacerbates autoimmune aortitis in IL-1 receptor antagonist-deficient mice
- IL1R1 is required for celastrol's leptin-sensitization and antiobesity effects
- IL1RN mediates the suppressive effect of methionine deprivation on glioma proliferation
- Increase in the Number of Bone Marrow Osteoclast Precursors at Different Skeletal Sites, Particularly in Long Bone and Jaw Marrow in Mice Lacking IL-1RA
- Increased ILC3s associated with higher levels of IL-1β aggravates inflammatory arthritis in mice lacking phagocytic NADPH oxidase
- Infants with evolving bronchopulmonary dysplasia demonstrate monocyte-specific expression of IL-1 in tracheal aspirates
- Inhibition of interleukin-1 suppresses angiotensin II-induced aortic inflammation and aneurysm formation
- Inhibition of interleukin-6 signaling attenuates aortitis, left ventricular hypertrophy and arthritis in interleukin-1 receptor antagonist deficient mice
- Interleukin 1-beta, interleukin-1 receptor antagonist and vitamin D levels in children with atopic dermatitis
- Interleukin 1-β, interleukin-1 receptor antagonist and vitamin D levels in children with atopic dermatitis
- Interleukin-1 receptor inhibition reduces stroke size in a murine model of sickle cell disease
- Interleukin-1-Interleukin-17 Signaling Axis Induces Cartilage Destruction and Promotes Experimental Osteoarthritis
- Interleukin-22 Attenuated Renal Tubular Injury in Aristolochic Acid Nephropathy via Suppressing Activation of NLRP3 Inflammasome
- Interleukin-36 Receptor Signaling Attenuates Epithelial Wound Healing in C57BL/6 Mouse Corneas
- Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α
- Knockout of the KH-Type Splicing Regulatory Protein Drives Glomerulonephritis in MRL-Fas<sup>lpr</sup> Mice
- Long-term efficacy of canakinumab in hyperimmunoglobulin D syndrome
- Loss of IL-33 enhances elastase-induced and cigarette smoke extract-induced emphysema in mice
- Loss of interleukin 1 signaling causes impairment of microglia- mediated synapse elimination and autistic-like behaviour in mice
- Macrophage activation syndrome with acute hepatitis in a patient with adult-onset immunodeficiency with anti-interferon gamma antibodies: a case report
- Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis
- Majeed syndrome: description of a novel mutation and therapeutic response to bisphosphonates and IL-1 blockade with anakinra
- Markers of Mitochondrial Metabolism in Tumor Hypoxia, Systemic Inflammation, and Adverse Outcome of Rectal Cancer
- New variant in deficiency of interleukin-36 receptor antagonist syndrome (DITRA)
- New variant in the IL1RN-gene (DIRA) associated with late-onset, CRMO-like presentation
- Novel Majeed Syndrome-Causing LPIN2 Mutations Link Bone Inflammation to Inflammatory M2 Macrophages and Accelerated Osteoclastogenesis
- Overview of the rarest causes of fever in newborns: handy hints for the neonatologist
- Pediatric autoinflammatory bone disorders-a mini review with special focus on pathogenesis and inborn errors of immunity
- Placental thromboinflammation impairs embryonic survival by reducing placental thrombomodulin expression
- Practical Approach to Diagnosis and Management of IL-1-Mediated Autoinflammatory Diseases (CAPS, TRAPS, MKD, and DIRA)
- PTPN2 Regulates the Interferon Signaling and Endoplasmic Reticulum Stress Response in Pancreatic β-Cells in Autoimmune Diabetes
- Real-Life Indications of Interleukin-1 Blocking Agents in Hereditary Recurrent Fevers: Data From the JIRcohort and a Literature Review
- Recombinant Human Proteoglycan 4 Regulates Phagocytic Activation of Monocytes and Reduces IL-1β Secretion by Urate Crystal Stimulated Gout PBMCs
- Regular exercise stimulates endothelium autophagy via IL-1 signaling in ApoE deficient mice
- Roles of Interleukin-1 Receptor Antagonist in Prostate Cancer Progression
- S100A8/A9 is not essential for the development of inflammation and joint pathology in interleukin-1 receptor antagonist knockout mice
- Scoping review of biological treatment of deficiency of interleukin-36 receptor antagonist (DITRA) in children and adolescents
- Second-line chemoimmunotherapy with nivolumab and paclitaxel in immune-related biomarker-enriched advanced gastric cancer: a multicenter phase Ib/II study
- Self-supervised learning for medical image analysis: Discriminative, restorative, or adversarial?
- Severe autoinflammation in 4 patients with C-terminal variants in cell division control protein 42 homolog (CDC42) successfully treated with IL-1β inhibition
- Sideroblastic anaemia, immunodeficiency, periodic fevers and developmental delay (SIFD) presenting as systemic inflammation with arthritis
- Spectrum of Genetic Autoinflammatory Diseases Presenting with Cutaneous Symptoms
- Spectrum of Systemic Auto-Inflammatory Diseases in India: A Multi-Centric Experience
- Steroid receptor coactivator-3 inhibition generates breast cancer antitumor immune microenvironment
- Supplementation of diet with non-digestible oligosaccharides alters the intestinal microbiota, but not arthritis development, in IL-1 receptor antagonist deficient mice
- Systemic and Nodular Hyperinflammation in a Patient with Refractory Familial Hemophagocytic Lymphohistiocytosis 2
- The 2021 EULAR/American College of Rheumatology points to consider for diagnosis, management and monitoring of the interleukin-1 mediated autoinflammatory diseases: cryopyrin-associated periodic syndromes, tumour necrosis factor receptor-associated period
- The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis
- The IL1RN Mutation Creating the Most-Upstream Premature Stop Codon Is Hypomorphic Because of a Reinitiation of Translation
- The Novel Tetra-Specific Drug C-192, Conjugated Using UniStac, Alleviates Non-Alcoholic Steatohepatitis in an MCD Diet-Induced Mouse Model
- The systemic autoinflammatory disorders for dermatologists. Part 2: disease examples
- Therapeutic potential of dinitrobenzene sulfonic acid (DNBS)-induced colitis in mice by targeting IL-1β and IL-18
- Toll-Like Receptor 5 Signaling Ameliorates Liver Fibrosis by Inducing Interferon β-Modulated IL-1 Receptor Antagonist in Mice
- Towards a Treatment for Neuroinflammation in Epilepsy: Interleukin-1 Receptor Antagonist, Anakinra, as a Potential Treatment in Intractable Epilepsy
- Tumor-derived interleukin-1 receptor antagonist exhibits immunosuppressive functions and promotes pancreatic cancer
- Tumour necrosis factor alpha, interleukin 1 beta and interferon gamma have detrimental effects on equine tenocytes that cannot be rescued by IL-1RA or mesenchymal stromal cell-derived factors
- Type I interferon-driven susceptibility to Mycobacterium tuberculosis is mediated by IL-1Ra
- Unveiling the Efficacy, Safety, and Tolerability of Anti-Interleukin-1 Treatment in Monogenic and Multifactorial Autoinflammatory Diseases
- Variation of sexual dimorphism and asymmetry in disease expression of inflammatory arthritis among laboratory mouse models with different genomic backgrounds
- When neonatal inflammation does not mean infection: an early-onset mevalonate kinase deficiency with interstitial lung disease
- Whole-exome sequencing in a subject with fluctuating neuropsychiatric symptoms, immunoglobulin G1 deficiency, and subsequent development of Crohn's disease: a case report
- Young and aged TLR4 deficient mice show sex-dependent enhancements in spatial memory and alterations in interleukin-1 related genes