• A double heterozygote for familial hypercholesterolaemia and familial defective apolipoprotein B-100
• A genetic and clinical study in a family with familial hypercholesterolemia
• A novel method for measuring intestinal and hepatic triacylglycerol kinetics
• A novel pathogenic variant of the LDLR gene in the Asian population and its clinical correlation with familial hypercholesterolemia
• A Rare Mutation in The <em>APOB</em> Gene Associated with Neurological Manifestations in Familial Hypobetalipoproteinemia
• Adduction of cholesterol 5,6-secosterol aldehyde to membrane-bound myelin basic protein exposes an immunodominant epitope
• All signs of metabolic syndrome in the hypertensive ISIAH rats are associated with increased activity of transcription factors PPAR, LXR, PXR, and CAR in the liver
• ANGPTL3 deficiency impairs lipoprotein production and produces adaptive changes in hepatic lipid metabolism
• Apolipoprotein B100 biogenesis: a complex array of intracellular mechanisms regulating folding, stability, and lipoprotein assembly
• Arylacetamide deacetylase: a novel host factor with important roles in the lipolysis of cellular triacylglycerol stores, VLDL assembly and HCV production
• AUP1 (Ancient Ubiquitous Protein 1) Is a Key Determinant of Hepatic Very-Low-Density Lipoprotein Assembly and Secretion
• Body mass index and glycemic control influence lipoproteins in children with type 1 diabetes
• Changes in Serum Lipid Profiles in Patients with Familial Hypercholesterolemia Who Smoke: A Pilot Study
• Characteristics of lipid metabolism under different urinary protein excretion in children with primary nephrotic syndrome
• Characterization of a mutant form of human apolipoprotein B (Thr26_Tyr27del) associated with familial hypobetalipoproteinemia
• Chronic kidney disease delays VLDL-apoB-100 particle catabolism: potential role of apolipoprotein C-III
• Chylomicronemia elicits atherosclerosis in mice--brief report
• Contribution of intestinal triglyceride-rich lipoproteins to residual atherosclerotic cardiovascular disease risk in individuals with type 2 diabetes on statin therapy
• CSF-Based Analysis for Identification of Potential Serum Biomarkers of Neural Tube Defects
• Decreased bone mineral density in subjects carrying familial defective apolipoprotein B-100
• DIAgnosis and Management Of familial hypercholesterolemia in a Nationwide Design (DIAMOND-FH): Prevalence in Switzerland, clinical characteristics and the diagnostic value of clinical scores
• Disruption of the ERLIN-TM6SF2-APOB complex destabilizes APOB and contributes to non-alcoholic fatty liver disease
• Does dietary folic acid supplementation in mouse NTD models affect neural tube development or gamete preference at fertilization?
• Effect of a splice site mutation in LDLR gene and two variations in PCSK9 gene in Tunisian families with familial hypercholesterolaemia
• Effect of apolipoprotein E genotype on apolipoprotein B-100 metabolism in normolipidemic and hyperlipidemic subjects
• Effect of ezetimibe on hepatic fat, inflammatory markers, and apolipoprotein B-100 kinetics in insulin-resistant obese subjects on a weight loss diet
• Effect of the R92H and A379V genotypes of platelet-activating factor acetylhydrolase on its enzyme activity, oxidative stress and metabolic profile in Chinese women with polycystic ovary syndrome
• Effects of bariatric surgery on hepatic and intestinal lipoprotein particle metabolism in obese, nondiabetic humans
• Effects of soy consumption on serum lipids and apoproteins in peritoneal dialysis patients: a randomized controlled trial
• Efficacy of alirocumab in 1191 patients with a wide spectrum of mutations in genes causative for familial hypercholesterolemia
• Estrogen enhances secretion of apolipoprotein B-100 containing lipoproteins by BeWo cells
• Estrogen treatment after ovariectomy protects against fatty liver and may improve pathway-selective insulin resistance
• Familial combined hyperlipidemia is associated with alterations in the cholesterol synthesis pathway
• Familial defective apolipoprotein B-100 and increased low-density lipoprotein cholesterol and coronary artery calcification in the old order amish
• Familial defective apolipoprotein B-100: A review
• Familial defective apolipoprotein B-100: a tale of twin mutations
• Familial hypercholesterolemia: epidemiology, Neolithic origins and modern geographic distribution
• Familial Hypercholesterolemia: Real-World Data of 1236 Patients Attending a Czech Lipid Clinic. A Retrospective Analysis of Experience in More than 50 years. Part I: Genetics and Biochemical Parameters
• Familial Hypercholesterolemia: Real-World Data of 1236 Patients Attending a Czech Lipid Clinic. A Retrospective Analysis of Experience in More than 50 years. Part II. Clinical Characteristics
• Familial hypobetalipoproteinemia in a hospital survey: genetics, metabolism and non-alcoholic fatty liver disease
• Fatty liver and insulin resistance: not always linked
• Fibrinogen Gamma Chain Mutations Provoke Fibrinogen and Apolipoprotein B Plasma Deficiency and Liver Storage
• Genetic basis of index patients with familial hypercholesterolemia in Chinese population: mutation spectrum and genotype-phenotype correlation
• GENetic characteristics and REsponse to lipid-lowering therapy in familial hypercholesterolemia: GENRE-FH study
• Genetic screening for homozygous and heterozygous familial hypercholesterolemia
• Genomic characterization of two deletions in the LDLR gene in Tunisian patients with familial hypercholesterolemia
• Homozygous autosomal dominant hypercholesterolaemia in the Netherlands: prevalence, genotype-phenotype relationship, and clinical outcome
• Homozygous Familial Hypercholesterolemia Patients With Identical Mutations Variably Express the LDLR (Low-Density Lipoprotein Receptor): Implications for the Efficacy of Evolocumab
• Homozygous MTTP and APOB mutations may lead to hepatic steatosis and fibrosis despite metabolic differences in congenital hypocholesterolemia
• Huh-7 or HepG2 cells: which is the better model for studying human apolipoprotein-B100 assembly and secretion?
• Identification and functional characterization of LDLR mutations in familial hypercholesterolemia patients from Southern Italy
• Identification of protein disulfide isomerase 1 as a key isomerase for disulfide bond formation in apolipoprotein B100
• Immunochemical analysis of the electronegative LDL subfraction shows that abnormal N-terminal apolipoprotein B conformation is involved in increased binding to proteoglycans
• Impaired HDL (High-Density Lipoprotein)-Mediated Macrophage Cholesterol Efflux in Patients With Abdominal Aortic Aneurysm-Brief Report
• Impaired VLDL assembly: a novel mechanism contributing to hepatic lipid accumulation following ovariectomy and high-fat/high-cholesterol diets?
• In Silico Analysis of CatSper Family Genes and APOB Gene Regulation in Male Infertility
• Increased whole-body adiposity without a concomitant increase in liver fat is not associated with augmented metabolic dysfunction
• Inverse expression of estrogen receptor alpha and apolipoprotein B in coronary intimal hyperplasia of surgically repaired congenital heart disease: a pre-atherosclerotic condition?
• Lack of cardiovascular disease among old order amish with familial defective apolipoprotein B
• Lipid droplets are arrested in the ER membrane by tight binding of lipidated apolipoprotein B-100
• Lipid profile and concentration of ApoA-1 and ApoB-100 in patients with end-stage renal disease treated by repeated haemodialysis
• Lipoprotein(A) with An Intact Lysine Binding Site Protects the Retina From an Age-Related Macular Degeneration Phenotype in Mice (An American Ophthalmological Society Thesis)
• Loss and gain of function of Grp75 or mitofusin 2 distinctly alter cholesterol metabolism, but all promote triglyceride accumulation in hepatocytes
• Low-density lipoprotein lowering in 2013 by nonstatin agents: the discovery and development of promising novel targeted therapies
• Low-dose dexamethasone administration for 3 weeks favorably affects plasma HDL concentration and composition but does not affect very low-density lipoprotein kinetics
• Management of non-high-density lipoprotein abnormalities
• Mesoporous Few-Layer Graphene Platform for Affinity Biosensing Application
• Mipomersen, an antisense oligonucleotide to apolipoprotein B-100, reduces lipoprotein(a) in various populations with hypercholesterolemia: results of 4 phase III trials
• Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial
• miR-130b is a potent stimulator of hepatic very-low-density lipoprotein assembly and secretion via marked induction of microsomal triglyceride transfer protein
• Molecular description of familial defective APOB-100 in Malaysia
• Molecular genetics of hypercholesterolemia
• Monogenic and polygenic causes of low and extremely low LDL-C levels in patients referred to specialty lipid clinics: Genetics of low LDL-C
• Mutational analysis and genotype-phenotype relation in familial hypercholesterolemia: The SAFEHEART registry
• Mutations in RAD21 disrupt regulation of APOB in patients with chronic intestinal pseudo-obstruction
• Novel treatments for familial hypercholesterolemia: pharmacogenetics at work
• Oxidative modification of lipoproteins: mechanisms, role in inflammation and potential clinical applications in cardiovascular disease
• PCSK9 inhibitor therapy in homozygous familial defective apolipoprotein B-100 due to APOB R3500Q: A case report
• Phenotype-genotype analyses of clinically diagnosed Malaysian familial hypercholestrolemic patients
• Phenotypic characterization and predictive analysis of p.Asp47Asn LDL receptor mutation associated with Familial Hypercholesterolemia in a Chilean population
• Phenotypic severity in a family with MEND syndrome is directly associated with the accumulation of potentially functional variants of cholesterol homeostasis genes
• Phenotypical, Clinical, and Molecular Aspects of Adults and Children With Homozygous Familial Hypercholesterolemia in Iberoamerica
• Phosphatidylcholine synthesis regulates triglyceride storage and chylomicron secretion by Caco2 cells
• Polygenic architecture and cardiovascular risk of familial combined hyperlipidemia
• Portal vein and systemic adiponectin concentrations are closely linked with hepatic glucose and lipoprotein kinetics in extremely obese subjects
• Predictive value of preoperative platelet-to-albumin ratio and apolipoprotein B-to-apolipoprotein A1 ratio for osteosarcoma in children and adolescents: a retrospective study of 118 cases
• Reproducibility of glucose, fatty acid and VLDL kinetics and multi-organ insulin sensitivity in obese subjects with non-alcoholic fatty liver disease
• Serum lipids, lipoproteins, and risk of breast cancer: a nested case-control study using multiple time points
• Serum plasminogen as a potential biomarker for the effects of low-dose benzene exposure
• Serum Sialic Acid Concentration and Content in ApoB-Containing Lipoproteins in Liver Diseases
• Significance of the lipid profile and endothelium-dependent vasodilatation in the pathogenesis of microvascular angina
• Spectrum of mutations in index patients with familial hypercholesterolemia in Singapore: Single center study
• Structural analysis of APOB variants, p.(Arg3527Gln), p.(Arg1164Thr) and p.(Gln4494del), causing Familial Hypercholesterolaemia provides novel insights into variant pathogenicity
• The role of adiposity, diet and inflammation on the discordance between LDL-C and apolipoprotein B
• Therapeutic Management of Familial Hypercholesterolemia: Current and Emerging Drug Therapies
• Therapeutic regulation of apoB100 metabolism in insulin resistance in vivo
• Treatment approaches for diabetes and dyslipidemia
• Two forms of familial hypercholesterolemia: differences in cardiovascular risk factors, cardiac and extracardiac atherosclerosis
• VLDL-specific increases of fatty acids in autism spectrum disorder correlate with social interaction
• α-Linolenic acid supplementation and exercise training reveal independent and additive responses on hepatic lipid accumulation in obese rats