• 11 beta-Hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excess
• 11 beta-Hydroxysteroid dehydrogenase: fact or fancy?
• 11 beta-Hydroxysteroid dehydrogenases: key enzymes in determining tissue-specific glucocorticoid effects
• 11 beta-hydroxysteroid-dehydrogenase: characteristics and the clinical significance of a key enzyme in cortisol metabolism
• 11beta-hydroxysteroid dehydrogenase and the pre-receptor regulation of corticosteroid hormone action
• 11beta-hydroxysteroid dehydrogenase type 1 deficiency ('apparent cortisone reductase deficiency') in a 6-year-old boy
• 11beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress
• 11beta-Hydroxysteroid Dehydrogenase Type 1 Regulation by Intracellular Glucose 6-Phosphate Provides Evidence for a Novel Link between Glucose Metabolism and Hypothalamo-Pituitary-Adrenal Axis Function
• 11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response
• 11beta-hydroxysteroide dehydrogenases. Recent advances
• 11β-Hydroxysteroid dehydrogenase 1: translational and therapeutic aspects
• 11β-hydroxysteroid dehydrogenases: intracellular gate-keepers of tissue glucocorticoid action
• 5 alpha-reductase activity in polycystic ovary syndrome
• A follow-up history of young man with apparent cortisone reductase deficiency (ACRD) - several years after diagnosis
• A non-isotopic method for estimating 11 beta hydroxysteroid dehydrogenase activity in vivo
• A study of the hexose-6-phosphate dehydrogenase gene R453Q and 11beta-hydroxysteroid dehydrogenase type 1 gene 83557insA polymorphisms in the polycystic ovary syndrome
• Abnormalities of glucose homeostasis and the hypothalamic-pituitary-adrenal axis in mice lacking hexose-6-phosphate dehydrogenase
• Activation of the hypothalamic-pituitary-adrenal axis in obesity: cause or consequence?
• Acute Statin Administration Reduces Levels of Steroid Hormone Precursors
• Adrenogenital syndrome with salt loss. 3-betahydroxysteroid dehydrogenase deficiency as a cause of life threatening vomiting with dehydration in newborn infants
• Alteration in glucocorticoids secretion and metabolism in patients affected by cystic fibrosis
• Alterations of Cortisol Metabolism in Human Disorders
• Analysis of the human gene encoding the kidney isozyme of 11 beta-hydroxysteroid dehydrogenase
• Apparent cortisone reductase deficiency: a functional defect in 11beta-hydroxysteroid dehydrogenase type 1
• Apparent cortisone reductase deficiency: a rare cause of hyperandrogenemia and hypercortisolism
• Apparent cortisone reductase deficiency: a unique form of hypercortisolism
• Association study of CYP17 and HSD11B1 in polycystic ovary syndrome utilizing comprehensive gene coverage
• Biomarkers of hypothalamic-pituitary-adrenal axis activity in mice lacking 11β-HSD1 and H6PDH
• Cloning of cDNA encoding an NAD(+)-dependent isoform of 11 beta-hydroxysteroid dehydrogenase in sheep kidney
• Cortisol metabolism and the role of 11beta-hydroxysteroid dehydrogenase
• Cortisol metabolism and visceral obesity: role of 11beta-hydroxysteroid dehydrogenase type I enzyme and reduced co-factor NADPH
• Cortisone-reductase deficiency associated with heterozygous mutations in 11beta-hydroxysteroid dehydrogenase type 1
• Crystal structure of human liver Delta4-3-ketosteroid 5beta-reductase (AKR1D1) and implications for substrate binding and catalysis
• Defects in the HSD11 gene encoding 11 beta-hydroxysteroid dehydrogenase are not found in patients with apparent mineralocorticoid excess or 11-oxoreductase deficiency
• Deficient inactivation of cortisol by 11 beta-hydroxysteroid dehydrogenase in essential hypertension
• Deoxycorticosterone inactivation by AKR1C3 in human mineralocorticoid target tissues
• Distinguishing primary from secondary Δ(4) -3-oxosteroid 5β-reductase (SRD5B1, AKR1D1) deficiency by urinary steroid analysis
• Does kidney transplantation normalise cortisol metabolism in apparent mineralocorticoid excess syndrome?
• Elevated 17-hydroxyprogesterone and testosterone in a newborn with 3-beta-hydroxysteroid dehydrogenase deficiency
• Elevated periimplantation uterine natural killer cell density in human endometrium is associated with impaired corticosteroid signaling in decidualizing stromal cells
• Estimation of reference curves for the urinary steroid metabolome in the first year of life in healthy children: Tracing the complexity of human postnatal steroidogenesis
• Failure of cortisone acetate treatment in congenital adrenal hyperplasia because of defective 11beta-hydroxysteroid dehydrogenase reductase activity
• Formation of threohydrobupropion from bupropion is dependent on 11β-hydroxysteroid dehydrogenase 1
• Gas chromatography-mass spectrometry profiling of steroids in urine of patients with acute intermittent porphyria
• Gas chromatography/mass spectrometry (GC/MS) remains a pre-eminent discovery tool in clinical steroid investigations even in the era of fast liquid chromatography tandem mass spectrometry (LC/MS/MS)
• Genetic variation in 11beta-hydroxysteroid dehydrogenase type 1 predicts adrenal hyperandrogenism among lean women with polycystic ovary syndrome
• Genetics of adrenocortical disease: an update
• Genotypes at 11beta-hydroxysteroid dehydrogenase type 11B1 and hexose-6-phosphate dehydrogenase loci are not risk factors for apparent cortisone reductase deficiency in a large population-based sample
• Growth hormone (GH) or insulin-like growth factor (IGF)-I represses 11beta-hydroxysteroid dehydrogenase type 1 (HSD1) mRNA expression in 3T3-L1 cells and its activity in their homogenates
• Hexose 6-phosphate dehydrogenase (H6PD) and corticosteroid metabolism
• Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11 beta-hydroxysteroid dehydrogenase type 1
• Hexose-6-phosphate dehydrogenase in the endoplasmic reticulum
• Hexose-6-phosphate dehydrogenase: a new risk gene for multiple sclerosis
• Human kidney 11 beta-hydroxysteroid dehydrogenase is a high affinity nicotinamide adenine dinucleotide-dependent enzyme and differs from the cloned type I isoform
• In-Depth Dissection of the P133R Mutation in Steroid 5β-Reductase (AKR1D1): A Molecular Basis of Bile Acid Deficiency
• Lack of Association of the 11beta-hydroxysteroid dehydrogenase type 1 gene 83,557insA and hexose-6-phosphate dehydrogenase gene R453Q polymorphisms with body composition, adrenal androgen production, blood pressure, glucose metabolism, and dementia
• Mast cells express 11β-hydroxysteroid dehydrogenase type 1: a role in restraining mast cell degranulation
• Medical and physiological aspects of the 11beta-hydroxysteroid dehydrogenase system
• Modulation of 11beta-hydroxysteroid dehydrogenase isozymes by growth hormone and insulin-like growth factor: in vivo and in vitro studies
• Modulation of cortisol metabolism by low-dose growth hormone replacement in elderly hypopituitary patients
• Modulation of glucocorticoid metabolism by the growth hormone - IGF-1 axis
• Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency
• Mutations of the hexose-6-phosphate dehydrogenase gene rarely cause hyperandrogenemic polycystic ovary syndrome
• NAD(+)-dependent isoform of 11 beta-hydroxysteroid dehydrogenase. Cloning and characterization of cDNA from sheep kidney
• Novel H6PDH mutations in two girls with premature adrenarche: 'apparent' and 'true' CRD can be differentiated by urinary steroid profiling
• Novel insight into etiology, diagnosis and management of primary adrenal insufficiency
• Pathophysiology of modulation of local glucocorticoid levels by 11beta-hydroxysteroid dehydrogenases
• Physiological roles of 11 beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase
• Premature adrenarche: novel lessons from early onset androgen excess
• Role of a disordered steroid metabolome in the elucidation of sterol and steroid biosynthesis
• Silent adrenal gland tumors in patients with adrenogenital syndrome
• Steroid biomarkers and genetic studies reveal inactivating mutations in hexose-6-phosphate dehydrogenase in patients with cortisone reductase deficiency
• The cortisol-cortisone shuttle and hypertension
• The expression of 11 beta-hydroxysteroid dehydrogenase type I by lymphocytes provides a novel means for intracrine regulation of glucocorticoid activities
• The functional consequences of 11beta-hydroxysteroid dehydrogenase expression in adipose tissue
• The importance of genetic counseling and genetic screening: a case report of a 16-year-old boy with resistant hypertension and severe hypokalemia
• The metabolism of cortisol by term baboon neonates (Papio papio)
• The syndrome of apparent mineralocorticoid excess: its association with 11 beta-dehydrogenase and 5 beta-reductase deficiency and some consequences for corticosteroid metabolism
• Tissue-specific Cushing's syndrome, 11beta-hydroxysteroid dehydrogenases and the redefinition of corticosteroid hormone action
• Transcription activation of mouse mammary tumor virus-chloramphenicol acetyltransferase: a model to study the metabolism of cortisol
• Variants implicated in cortisone reductase deficiency do not contribute to susceptibility to common forms of polycystic ovary syndrome