• <em>Tlr5</em> deficiency exacerbates lupus-like disease in the MRL/<em>lpr</em> mouse model
• A human immune system (HIS) mouse model that dissociates roles for mouse and human FcR⁺ cells during antibody-mediated immune responses
• A human immune system (HIS) mouse model that dissociates roles for mouse and human FcR+ cells during antibody-mediated immune responses
• A protective role for B-1 cells and oxidation-specific epitope IgM in lung fibrosis
• Adiponectin pathway activation dampens inflammation and enhances alveolar macrophage fungal killing via LC3-associated phagocytosis
• Advances in Understanding and Managing Myasthenia Gravis: Current Trends and Future Directions
• Analysis of Clinical, Immunological and Molecular Features of Leukocyte Adhesion Deficiency Type I in Egyptian Children
• Antibody Production after COVID-19 Vaccination in Patients with Inborn Errors of Immunity
• Autoinducer-2 promotes adherence of <em>Aeromonas veronii</em> through facilitating the expression of MSHA type IV pili genes mediated by c-di-GMP
• Bacterial outer membrane vesicles provide an alternative pathway for trafficking of <em>Escherichia coli</em> O157 type III secreted effectors to epithelial cells
• Blockade of C5a receptor unleashes tumor-associated macrophage antitumor response and enhances CXCL9-dependent CD8(+) T cell activity
• Blockade of C5a receptor unleashes tumor-associated macrophage antitumor response and enhances CXCL9-dependent CD8⁺ T cell activity
• Blockade of complement C5a receptor unleashes tumor-associated macrophage antitumor response and enhances CXCL9-dependent CD8⁺ T cell activity
• Bullous pemphigoid induced by IgG targeting type XVII collagen non-NC16A/NC15A extracellular domains is driven by Fc gamma receptor- and complement-mediated effector mechanisms and is ameliorated by neonatal Fc receptor blockade
• C3a/C3aR synergies with TGF-β to promote epithelial-mesenchymal transition of renal tubular epithelial cells via the activation of the NLRP3 inflammasome
• C3aR in the medial prefrontal cortex modulates the susceptibility to LPS-induced depressive-like behaviors through glutamatergic neuronal excitability
• C5aR2 Deficiency Lessens C5aR1 Distribution and Expression in Neutrophils and Macrophages
• CD11b Deficiency Favors Cartilage Calcification via Increased Matrix Vesicles, Apoptosis, and Lysyl Oxidase Activity
• CD31 signaling promotes the detachment at the uropod of extravasating neutrophils allowing their migration to sites of inflammation
• CD4⁺ T cell-induced inflammatory cell death controls immune-evasive tumours
• CD44 acts as a coreceptor for cell-specific enhancement of signaling and regulatory T cell induction by TGM1, a parasite TGF-β mimic
• CD9 Counteracts Liver Steatosis and Mediates GCGR Agonist Hepatic Effects
• CD93 Ameliorates Diabetic Wounds by Promoting Angiogenesis via the p38MAPK/MK2/HSP27 Axis
• Clinical and immunological characteristics of 69 leukocyte adhesion deficiency-I patients
• Clinical manifestations and expression of CD18 to guide the diagnosis of leukocyte adhesion deficiency type 1: Mexico experience
• Complement 3a Receptor 1 on Macrophages and Kupffer cells is not required for the Pathogenesis of Metabolic Dysfunction-Associated Steatotic Liver Disease
• Complement C3 deficient mice show more severe imiquimod-induced psoriasiform dermatitis than wild-type mice regardless of the commensal microbiota
• Complement C3-Deficiency-Induced Constipation in FVB/N-C3(em1Hlee)/Korl Knockout Mice Was Significantly Relieved by Uridine and Liriope platyphylla L. Extracts
• Complement C3-Deficiency-Induced Constipation in FVB/N-C3^em1Hlee/Korl Knockout Mice Was Significantly Relieved by Uridine and <em>Liriope platyphylla</em> L. Extracts
• Complement C5a Receptor Signaling Alters Stress Responsiveness and Modulates Microglia Following Chronic Stress Exposure
• Complement or Insult: the emerging link between complement cascade deficiencies and pathology of myeloid malignancies
• Complement receptor 3 is required for maximum in vitro trogocytic killing of the parasite Trichomonas vaginalis by human neutrophil-like cells
• Complement receptor 3-mediated neurotoxic glial activation contributes to rotenone-induced cognitive decline in mice
• Complement Receptor C3aR1 Contributes to Paclitaxel-Induced Peripheral Neuropathic Pain in Mice and Rats
• CRIg+ macrophages deficiency enhanced inflammation damage in IBD due to gut extracellular vesicles containing microbial DNA
• Cutting Edge: Optimal Formation of Hepatic Tissue-Resident Memory CD4 T Cells Requires T-bet Regulation of CD18
• Deficiency of Complement C3a and C5a receptors Does Not Prevent Angiotensin II-Induced Hypertension and Hypertensive End-Organ Damage
• Deletion of Talin1 in Myeloid Cells Facilitates Atherosclerosis in Mice
• Deletion of Tmem268 in mice suppresses anti-infectious immune responses by downregulating CD11b signaling
• Deucrictibant for angioedema due to acquired C1-inhibitor deficiency: A randomized-controlled trial
• Effectiveness of a novel rat model of off-target PLA2R1 knockout to renal impairment
• Efgartigimod restores muscle function in a humanized mouse model of immune-mediated necrotizing myopathy
• Emerging role of C5aR2: novel insights into the regulation of uterine immune cells during pregnancy
• Endogenous complement-activating IgM is not required for primary antibody responses but promotes plasma cell differentiation and secondary antibody responses to a large particulate antigen in mice
• Endoplasmic Reticulum Protein 72 Regulates Integrin Mac-1 Activity to Influence Neutrophil Recruitment
• Expanding options of supportive care in IgA nephropathy
• Fcgr2b and Fcgr3 are the major genetic factors for cartilage antibody-induced arthritis, overriding the effect of Hc encoding complement C5
• Fibroblast growth factor receptor 4 deficiency in macrophages aggravates experimental colitis by promoting M1-polarization
• Filtration and tubular handling of EWE-hC3Nb1, a complement inhibitor nanobody, in wild type mice and a mouse model of proteinuric kidney disease
• Functions and Clinical Relevance of Liver-Derived Immunoglobulins
• Gasdermin D drives focal crystalline thrombotic microangiopathy by accelerating immunothrombosis and necroinflammation
• Genetic manipulation of an <em>Ixodes scapularis</em> cell line
• Germline knockout of <em>Nr2e3</em> protects photoreceptors in three distinct mouse models of retinal degeneration
• Helicase-like transcription factor (Hltf)-deletion activates Hmgb1-Rage axis and granzyme A-mediated killing of pancreatic β cells resulting in neonatal lethality
• Identification and structural analysis of dimeric chicken complement component 3d and its binding with chicken complement receptor 2
• IgA nephropathy
• Immunodeficiency
• Increased thromboinflammatory load in hereditary angioedema
• Influence of complement protein C1q or complement receptor C5aR1 on gut microbiota composition in wildtype and Alzheimer's mouse models
• Integrins in Health and Disease-Suitable Targets for Treatment?
• Intestinal epithelium dysfunctions cause IgA deposition in the kidney glomeruli of intestine-specific Ap1m2-deficient mice
• ITGB2-ICAM1 axis promotes liver metastasis in BAP1-mutated uveal melanoma with retained hypoxia and ECM signatures
• Local complement activation and modulation in mucosal immunity
• Loss of NLRP6 expression increases the severity of intestinal injury after syngeneic hematopoietic stem cell transplantation
• Mac-1 deficiency ameliorates pressure overloaded heart failure through inhibiting macrophage polarization and activation
• Macrophage-1 antigen exacerbates histone-induced acute lung injury and promotes neutrophil extracellular trap formation
• Mass cytometric analysis of the immune cell landscape after traumatic brain injury elucidates the role of complement and complement receptors in neurologic outcomes
• Migratory CD103⁺CD11b⁺ cDC2s in Peyer's patches are critical for gut IgA responses following oral immunization
• Mitochondrial damage and clearance in retinal pigment epithelial cells
• Monocyte NLRP3 inflammasome and interleukin-1beta activation modulated by alpha-1 antitrypsin therapy in deficient individuals
• Multicolor flow cytometry in clinical samples for platelet signaling assessment
• Nuclear Factor kappaB Signaling Deficiency in CD11c-Expressing Phagocytes Mediates Early Inflammatory Responses and Enhances Mycobacterium tuberculosis Control
• Pharmacologic Manipulation of Complement Receptor 3 Prevents Dendritic Spine Loss and Cognitive Impairment After Acute Cranial Radiation
• Platelets interact with CD169⁺ macrophages and cDC1 and enhance liposome-induced CD8⁺ T cell responses
• Proteomics analysis of coronary atherosclerotic heart disease with different Traditional Chinese Medicine syndrome types before and after percutaneous coronary intervention
• Rare Autoimmune Diseases Role of Genetics - Example of Systemic Lupus Erythematosus
• Rare genetic causes of meningitis and encephalitis
• Receptor tyrosine kinases Tyro3, Axl, and Mertk differentially contribute to antibody-induced arthritis
• Reduced decay-accelerating factor expression promotes complement-mediated cystogenesis in murine ADPKD
• Repressive Control of Keratinocyte Cytoplasmic Inflammatory Signaling
• Restoring SRSF3 in Kupffer cells attenuates obesity-related insulin resistance
• RGC-32 mediates proinflammatory and profibrotic pathways in immune-mediated kidney disease
• Ribosome biogenesis controls cranial suture MSC fate via the complement pathway in mouse and human iPSC models
• Role of the anaphylatoxin receptor C5aR2 in angiotensin II induced hypertension and hypertensive end organ damage
• SKAP2 acts downstream of CD11b/CD18 and regulates neutrophil effector function
• Soluble Enolase 1 of Candida albicans and Aspergillus fumigatus Stimulates Human and Mouse B Cells and Monocytes
• Sparsentan ameliorates glomerular hypercellularity and inflammatory-gene networks induced by IgA1-IgG immune complexes in a mouse model of IgA nephropathy
• Structure and function of therapeutic antibodies approved by the US FDA in 2023
• Sweet syndrome associated with moderate leukocyte adhesion deficiency type I: a case report and review of the literature
• Synergy of de-walled Ganoderma Lucidum spore powder (GLSP) on targeted therapy in advanced non-squamous non-small cell lung cancer with epidermal growth factor receptor (EGFR) mutant: protocol for a randomized, double-blind, placebo-controlled study
• Targeting complement C3a receptor resolves mitochondrial hyperfusion and subretinal microglial activation in progranulin-deficient frontotemporal dementia
• The C-Type Lectin Receptor CD93 Regulates Platelet Activation and Surface Expression of the Protease Activated Receptor 4
• The complement regulator CD55 modulates TLR9 signaling and supports survival in marginal zone B cells
• The Complement-Targeted Inhibitor Mini-FH Protects against Experimental Periodontitis via Both C3-Dependent and C3-Independent Mechanisms
• The integrin CD11b inhibits MSU-induced NLRP3 inflammasome activation in macrophages and protects mice against MSU-induced joint inflammation
• The role of C5aR1-mediated hepatic macrophage efferocytosis in NASH
• Tlr5 deficiency exacerbates lupus-like disease in the MRL/lpr mouse model
• TREM2 regulates microglial phagocytosis of synapses in innate immune tolerance
• Vitamin A and vitamin D3 protect the visual apparatus during the development of dopamine-2 receptor knockout mouse model of Parkinsonism
• Vitamin D and immune system