• A novel chimeric active immunization mouse model of PLA2R1-associated membranous nephropathy
• A novel flavonol-polysaccharide from Tamarix chinensis alleviates influenza A virus-induced acute lung injury. Evidences for its mechanism of action
• A real-world study and network pharmacology analysis of EGFR-TKIs combined with ZLJT to delay drug resistance in advanced lung adenocarcinoma
• A survey of the adaptive immune genes of the polka-dot batfish Ogcocephalus cubifrons
• Adaptive and Innate Immunity Are Key Drivers of Age at Onset of Multiple Sclerosis
• An Immunoreceptor-Targeting Strategy with Minimalistic C3b Peptide Fusion Enhances SARS-CoV-2 RBD mRNA Vaccine Immunogenicity
• Androgen-regulated stromal complement component 7 (C7) suppresses prostate cancer growth
• Angiogenic factors and the lectin pathway of complement in women with secondary recurrent pregnancy loss
• beta-Sitosterol activates autophagy to inhibit the development of hepatocellular carcinoma by regulating the complement C5a receptor 1/alpha fetoprotein axis
• C3a/C3aR synergies with TGF-β to promote epithelial-mesenchymal transition of renal tubular epithelial cells via the activation of the NLRP3 inflammasome
• C5a stimulation induces caspase-1 activation and mature IL-1beta production in human peripheral blood mononuclear cells
• C5a-C5aR1 axis controls mitochondrial fission to promote podocyte injury in lupus nephritis
• Calycosin ameliorates osteoarthritis by regulating the imbalance between chondrocyte synthesis and catabolism
• CD5L is a canonical component of circulatory IgM
• Cepharanthine synergistically promotes methylprednisolone pharmacodynamics against human peripheral blood mononuclear cells possibly via regulation of P-glycoprotein/glucocorticoid receptor translocation
• Circular RNA expression profiles and circRNA-miRNA-mRNA crosstalk in pre-eclamptic placenta
• Comparison of the broncoalveolar lavage fluid proteomics between foals and adult horses
• Complement C1q essential for aeroallergen sensitization via CSF1R(+) conventional dendritic cells type 2
• Complement C1q essential for aeroallergen sensitization via CSF1R⁺ conventional dendritic cells type 2
• Complement C3aR signaling: Immune and metabolic modulation and its impact on Alzheimer's disease
• Complement components regulates ferroptosis in CVB3 viral myocarditis by interatction with TFRC
• Complement is activated by elevated IgG3 hexameric platforms and deposits C4b onto distinct antibody domains
• Complement or Insult: the emerging link between complement cascade deficiencies and pathology of myeloid malignancies
• Complement protein signatures in patients with alcohol-associated hepatitis
• Complement receptor 3-dependent engagement by Candida glabrata beta-glucan modulates dendritic cells to induce regulatory T-cell expansion
• Conformational variants of the ternary complex of C5a, C5aR1, and G-protein
• Cordyceps protein alleviates renal injury by inhibiting T cell infiltration and Th1 cell differentiation in lupus nephritis mice
• CSMD1 regulates brain complement activity and circuit development
• Danlou Recipe promotes cholesterol efflux in macrophages RAW264.7 and reverses cholesterol transport in mice with hyperlipidemia induced by P407
• Deficiency of Complement C3a and C5a receptors Does Not Prevent Angiotensin II-Induced Hypertension and Hypertensive End-Organ Damage
• Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition
• Discovery and Characterization of a New Class of C5aR1 Antagonists Showing <em>In Vivo</em> Activity
• Dysregulated complement activation during acute myocardial infarction leads to endothelial glycocalyx degradation and endothelial dysfunction via the C5a:C5a-Receptor1 axis
• Elucidating the Mechanisms of Sodium Benzoate in Alzheimer Disease: Insights from Quantitative Proteomics Analysis of Serum Samples
• Elucidating the Mechanisms of Sodium Benzoate in Alzheimer's Disease: Insights from Quantitative Proteomics Analysis of Serum Samples
• Enrichment of oligodendrocyte precursor phenotypes in subsets of low-grade glioneuronal tumours
• Erzhi pills reverse PD-L1-mediated immunosuppression in melanoma microenvironment
• Evaluation of genetic response of mesenchymal stem cells to nanosecond pulsed electric fields by whole transcriptome sequencing
• Exploring bacterial community composition and immune gene expression of European eel larvae (Anguilla anguilla) in relation to first-feeding diets
• Expression of genes encoding non-specific immunity, anti-oxidative status and aquaporins in β-glucan-fed golden mahseer (<em>Tor putitora</em>) juveniles under ammonia stress
• Fatal Overdose with the Cannabinoid Receptor Agonists MDMB-4en-PINACA and 4F-ABUTINACA: A Case Report and Review of the Literature
• Ficolin 3 promotes ferroptosis in HCC by downregulating IR/SREBP axis-mediated MUFA synthesis
• Flavonoid compound from Agrimonia pilosa Ledeb improves adipose insulin resistance by alleviating oxidative stress and inflammation
• Follicular fluid C3a-peptide promotes oocyte maturation through F-actin aggregation
• Formation of chronic morphine withdrawal memories requires C1QL3-mediated regulation of PSD95 in the mouse basolateral amygdala
• GABA co-released from striatal dopamine axons dampens phasic dopamine release through autoregulatory GABA(A) receptors
• Ge-Gen-Qin-Lian decoction alleviates the symptoms of type 2 diabetes mellitus with inflammatory bowel disease via regulating the AGE-RAGE pathway
• Identifying Sex-Specific Serum Patterns of Alzheimer's Mice through Deep TMT Profiling and a Concentration-Dependent Concatenation Strategy
• IgA nephropathy
• Immediate Hypersensitivity Reactions
• Immediate Hypersensitivity Reactions (Archived)
• Immune thrombocytopenia: a review on the pathogenetic role of immune cells
• Immune-Modulating Effects of Low-Carbohydrate Ketogenic Foods in Healthy Canines
• Influence of complement protein C1q or complement receptor C5aR1 on gut microbiota composition in wildtype and Alzheimer's mouse models
• Inhibition of C5aR1 as a promising approach to treat taxane-induced neuropathy
• Innate Immune Sensing of AAV Vectors
• Innate Immune Sensing of Adeno-Associated Virus Vectors
• Intrathecal gastrodin alleviates allodynia in a rat spinal nerve ligation model through NLRP3 inflammasome inhibition
• Introduction of a novel chimeric active immunization mouse model of PLA2R1-associated membranous nephropathy
• JR14a: A novel antagonist of C3aR attenuates neuroinflammation in cerebral ischemia-reperfusion injury
• Junctional Adhesion Molecule (JAM)-C recruitment of Pard3 and drebrin to cell contacts initiates neuron-glia recognition and layer-specific cell sorting in developing cerebella
• Low-dose exercise protects the heart against established myocardial infarction via IGF-1-upregulated CTRP9 in male mice
• Lysis and phenotypic modulation of mesenchymal stromal cells upon blood contact triggers anti-inflammatory skewing of the peripheral innate immune repertoire
• Macrophage-mediated trogocytosis contributes to destroying human schistosomes in a non-susceptible rodent host, Microtus fortis
• Manipulated C5aR1 over/down-expression associates with IL-6 expression during bacterial inflammation in half-smooth tongue sole (Cynoglossus semilaevis)
• Mechanistic insights into complement pathway inhibition by CR1 domain duplication
• Mitochondrial damage and clearance in retinal pigment epithelial cells
• Monocyte NLRP3 inflammasome and interleukin-1beta activation modulated by alpha-1 antitrypsin therapy in deficient individuals
• Monocyte-Mediated Thrombosis Linked to Circulating Tissue Factor and Immune Paralysis in COVID-19
• Multicolor flow cytometry in clinical samples for platelet signaling assessment
• Network pharmacology and experimental validation to study the potential mechanism of Tongguanteng injection in regulating apoptosis in osteosarcoma
• Network Pharmacology and Molecular Docking Explore the Mechanism of Mubiezi-Yinyanghuo Herb Pair in the Treatment of Rheumatoid Arthritis
• Neutrophil-inflicted vasculature damage suppresses immune-mediated optic nerve regeneration
• Peptidoglycan from Bacillus anthracis Inhibits Human Macrophage Efferocytosis in Part by Reducing Cell Surface Expression of MERTK and TIM-3
• Pharmacological and clinical profiles of avacopan (TAVNEOS() capsule), a selective C5a receptor antagonist
• Pharmacological and clinical profiles of avacopan (TAVNEOS^® capsule), a selective C5a receptor antagonist
• PPARα/γ-Targeting Amorfrutin Phytocannabinoids from Aerial Parts of <em>Glycyrrhiza foetida</em>
• Precision medicine in lupus nephritis
• Proteomic map of the differentially expressed proteins in the skin of <em>Ctenopharyngodon idella</em> against <em>Aeromonas hydrophila</em> infection
• Proteomic map of the differentially expressed proteins in the skin of Ctenopharyngodon idella against Aeromonas hydrophila infection
• Proteomics identifies complement protein signatures in patients with alcohol-associated hepatitis
• Radiomics Features on Magnetic Resonance Images Can Predict C5aR1 Expression Levels and Prognosis in High-Grade Glioma
• Refractory IgA Nephropathy: A Challenge for Future Nephrologists
• Role of genetics in eleven of the most common autoimmune diseases in the post genome-wide association studies era
• Serum amyloid P component: Structure, biological activity, and application in diagnosis and treatment of immune-associated diseases
• Sparsentan ameliorates glomerular hypercellularity and inflammatory-gene networks induced by IgA1-IgG immune complexes in a mouse model of IgA nephropathy
• STING inhibition suppresses microglia-mediated synapses engulfment and alleviates motor functional deficits after stroke
• Successful treatment of coexisting membranous nephropathy and immune thrombocytopenia by eradicating gastric Helicobacter pylori infection: a case report
• Synbiotics improve growth performance and nutrient digestibility, inhibit PEDV infection, and prevent intestinal barrier dysfunction by mediating innate antivirus immune response in weaned piglets
• Ternary model structural complex of C5a, C5aR2, and β-arrestin1
• The C5aR1 complement receptor: A novel immunomodulator of insulin action in skeletal muscle
• The gut microbiome regulates astrocyte reaction to Aβ amyloidosis through microglial dependent and independent mechanisms
• The Plasminogen-Apple-Nematode (PAN) domain suppresses JA/ET defense pathways in plants
• The RALF signaling pathway regulates cell wall integrity during pollen tube growth in maize
• Toll-Like Receptor mRNA Levels in Schizophrenia: Association With Complement Factors and Cingulate Gyrus Cortical Thinning
• Unveiling the role of miR-137-3p/miR-296-5p/SERPINA3 signaling in colorectal cancer progression: integrative analysis of gene expression profiles and in vitro studies
• Urine Proteomics Link Complement Activation with Interstitial Fibrosis/Tubular Atrophy in Lupus Nephritis Patients
• Weighted gene co-expression network analysis reveals key biomarkers and immune infiltration characteristics for bronchial epithelial cells from asthmatic patients
• Zilucoplan: First Approval
• β-Sitosterol activates autophagy to inhibit the development of hepatocellular carcinoma by regulating the complement C5a receptor 1/alpha fetoprotein axis