Disease: Complement component deficiency
- A complement atlas identifies interleukin-6-dependent alternative pathway dysregulation as a key druggable feature of COVID-19
- A homozygous loss-of-function C1S mutation is associated with Kikuchi-Fujimoto disease
- A novel method for assessment of human midpalatal sutures using CBCT-based geometric morphometrics and complexity scores
- Analgesic Effect of Exercise on Neuropathic Pain via Regulating the Complement Component 3 of Reactive Astrocytes
- Astrocyte-secreted C3 signaling impairs neuronal development and cognition in autoimmune diseases
- Bacterial outer membrane vesicles provide an alternative pathway for trafficking of <em>Escherichia coli</em> O157 type III secreted effectors to epithelial cells
- Biomimetic proteolipid vesicles for reverting GPI deficiency in paroxysmal nocturnal hemoglobinuria
- C-reactive protein binds to short phosphoglycan repeats of <em>Leishmania</em> secreted proteophosphoglycans and activates complement
- C3a/C3aR synergies with TGF-β to promote epithelial-mesenchymal transition of renal tubular epithelial cells via the activation of the NLRP3 inflammasome
- Capacity building and community of practice for women community health workers in low-resource settings: long-term evaluation of the Mobile University For Health (MUH)
- Case Report: C3 deficiency in two siblings
- Cell-autonomous regulation of complement C3 by factor H limits macrophage efferocytosis and exacerbates atherosclerosis
- Clinical Experience with Berotralstat in Patients with Hereditary Angioedema with Normal C1-Esterase Inhibitor: A Commented Case Series
- Combined transcriptomics and proteomics unveil the impact of vitamin C in modulating specific protein abundance in the mouse liver
- Complement
- Complement C1s deficiency in a male Caucasian patient with systemic lupus erythematosus: a case report
- Complement C3 Enhances LPS-Elicited Neuroinflammation and Neurodegeneration Via the Mac1/NOX2 Pathway
- Complement C3-Deficiency-Induced Constipation in FVB/N-C3<sup>em1Hlee</sup>/Korl Knockout Mice Was Significantly Relieved by Uridine and <em>Liriope platyphylla</em> L. Extracts
- Complement Component 5 (C5) Deficiency Improves Cognitive Outcome After Traumatic Brain Injury and Enhances Treatment Effects of Complement Inhibitors C1-Inh and CR2-Crry in a Mouse Model
- Complement in breast milk modifies offspring gut microbiota to promote infant health
- Complement or Insult: the emerging link between complement cascade deficiencies and pathology of myeloid malignancies
- Complement Receptor C3aR1 Contributes to Paclitaxel-Induced Peripheral Neuropathic Pain in Mice and Rats
- Complement Suppresses the Initial Type 1 Interferon Response to Ocular Herpes Simplex Virus Type 1 Infection in Mice
- Complement System Deficiencies in Elite Athletes
- Daily Injection of the β2 Adrenergic Agonist Clenbuterol Improved Muscle Glucose Metabolism, Glucose-Stimulated Insulin Secretion, and Hyperlipidemia in Juvenile Lambs Following Heat-Stress-Induced Intrauterine Growth Restriction
- Deficiency of Complement C3a and C5a receptors Does Not Prevent Angiotensin II-Induced Hypertension and Hypertensive End-Organ Damage
- EF1α-associated protein complexes affect dendritic spine plasticity by regulating microglial phagocytosis in Fmr1 knock-out mice
- Efficacy of GalNAc C3 siRNAs in factor H-deficient mice with C3 glomerulopathy
- Elevated expression of complement factor I in lung cancer cells associates with shorter survival - potentially via non-canonical mechanism
- Elevated expression of complement factor I in lung cancer cells associates with shorter survival-Potentially via non-canonical mechanism
- Emerging role of C5aR2: novel insights into the regulation of uterine immune cells during pregnancy
- Evaluating the efficacy and safety of pozelimab in patients with CD55 deficiency with hyperactivation of complement, angiopathic thrombosis, and protein-losing enteropathy disease: an open-label phase 2 and 3 study
- Factor H-related protein 1 promotes complement-mediated opsonization of Pseudomonas aeruginosa
- Functions and Clinical Relevance of Liver-Derived Immunoglobulins
- FVB/NJ strain as a mouse model for cutaneous leishmaniasis by Leishmania (L.) amazonensis
- Genetic bases of C7 deficiency: systematic review and report of a novel deletion determining functional hemizygosity
- Guardians of Immunity: Advances in Primary Immunodeficiency Disorders and Management
- Guidance to best tools and practices for systematic reviews
- Guidance to best tools and practices for systematic reviews
- Guidance to best tools and practices for systematic reviews1
- Helicase-like transcription factor (Hltf)-deletion activates Hmgb1-Rage axis and granzyme A-mediated killing of pancreatic β cells resulting in neonatal lethality
- HIV infection impairs the host response to Mycobacterium tuberculosis infection by altering surfactant protein D function in the human lung alveolar mucosa
- Human Inborn Errors of Immunity in Pyoderma Gangrenosum: A Systematic Review
- Identification and analysis of differential miRNA-mRNA interactions in coronary heart disease: an experimental screening approach
- Identification and structural analysis of dimeric chicken complement component 3d and its binding with chicken complement receptor 2
- IgA nephropathy
- IL1A enhances TNF-induced retinal ganglion cell death
- Influence of complement protein C1q or complement receptor C5aR1 on gut microbiota composition in wildtype and Alzheimer's mouse models
- Intracellular C3 protects β-cells from IL-1β-driven cytotoxicity via interaction with Fyn-related kinase
- IV iron formulations and use in adults
- Liver factor B silencing to cure C3 glomerulopathy: Evidence from a mouse model of complement dysregulation
- Mitochondrial damage and clearance in retinal pigment epithelial cells
- Monocyte NLRP3 inflammasome and interleukin-1beta activation modulated by alpha-1 antitrypsin therapy in deficient individuals
- Monogenic lupus with neuroregression in an infant due to rare compound heterozygous variants in C1QA gene: Case based review
- Monogenic lupus: Tracing the therapeutic implications from single gene mutations
- Mouse NOD/Shi and NSY/Hos strains infected with Plasmodium berghei ANKA are models for experimental cerebral malaria
- Multicolor flow cytometry in clinical samples for platelet signaling assessment
- Nutritional, bioactive components and health properties of the milpa triad system seeds (corn, common bean and pumpkin)
- Role of the Putative Histidine Kinase BP1092 in <em>Bordetella pertussis</em> Virulence Regulation and Intracellular Survival
- Sparsentan ameliorates glomerular hypercellularity and inflammatory-gene networks induced by IgA1-IgG immune complexes in a mouse model of IgA nephropathy
- Talazoparib enhances resection at DSBs and renders HR-proficient cancer cells susceptible to Polθ inhibition
- Targeting terminal pathway reduces brain complement activation, amyloid load and synapse loss, and improves cognition in a mouse model of dementia
- The complement regulator CD55 modulates TLR9 signaling and supports survival in marginal zone B cells
- The first case report of complement component 7 deficiency in Qatar and a 10-year follow-up
- The Role of Complement Component C3 in Protection Against <em>Pseudomonas</em> Pneumonia-Induced Lung Injury
- The Role of Complement Component C3 in Protection Against Pseudomonas Pneumonia-Induced Lung Injury
- The role of gamma globulin, complement component 1q, factor B, properdin, body temperature, C-reactive protein and serum amyloid alpha to the activity and the function of the human complement system and its pathways
- Three R2R3-MYB transcription factors from banana (Musa acuminata) activate structural anthocyanin biosynthesis genes as part of an MBW complex
- TYROBP/DAP12 knockout in Huntington's disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates astrogliosis and motor deterioration
- Unfolded Von Willebrand Factor Binds Protein S and Reduces Anticoagulant Activity
- Usefulness and analytical performances of complement multiplex assay for measuring complement biomarkers in plasma