• 12p rearrangement and DNA amplification mapped by comparative genomic hybridization in a patient with secondary myeloid leukemia
• 12q amplification defines a subtype of extraskeletal osteosarcoma with good prognosis that is the soft tissue homologue of parosteal osteosarcoma
• A 10-year survey, 1980-1990, of prenatally diagnosed small supernumerary marker chromosomes, identified by FISH analysis. Outcome and follow-up of 14 cases diagnosed in a series of 12,699 prenatal samples
• A miR-200c/141-BMI1 autoregulatory loop regulates oncogenic activity of BMI1 in cancer cells
• A series of supernumerary small ring marker autosomes identified by FISH with chromosome probe arrays and literature review excluding chromosome 15
• A well-differentiated liposarcoma with a new type of chromosome 12-derived markers
• Analysis of 20 genes at chromosome band 12q13: RACGAP1 and MCRS1 overexpression in nonsmall-cell lung cancer
• Array-based genotype-phenotype correlation in a case of supernumerary ring chromosome 12
• Association of microcephaly and cafe-au-lait spots in a patient with ring chromosome 12 syndrome
• Atypical lipomatous tumor with rare structural rearrangements involving chromosomes 8 and 12
• Atypical lipomatous tumor with structural rearrangements involving chromosomes 3 and 8
• Biology and Management of Deep-seated Atypical Lipomatous Tumor of the Extremities
• Characteristic chromosome abnormalities, including rearrangements of 6p, del(7q), +12, and t(12;14), in 44 uterine leiomyomas
• Characterization of a hotspot region on chromosome 12 for amplification in ring chromosomes in atypical lipomatous tumors
• Characterization of centromere alterations in liposarcomas
• Characterization of supernumerary rings and giant marker chromosomes in well-differentiated lipomatous tumors by a combination of G-banding, CGH, M-FISH, and chromosome- and locus-specific FISH
• Chromosomal changes detected by fluorescence in situ hybridization in patients with acute lymphoblastic leukemia
• Chromosomal changes in soft-tissue sarcomas. A new diagnostic parameter
• Chromosomal organization of amplified chromosome 12 sequences in mesenchymal tumors detected by fluorescence in situ hybridization
• Chromosomal origin of small ring marker chromosomes in man: characterization by molecular genetics
• Chromosomal rearrangements in patients with clinical features of Silver-Russell syndrome
• Chromosome 12 origin in rings and giant markers in well-differentiated liposarcoma
• Chronic myelomonocytic leukemia transformed from refractory anemia with ring sideroblasts with a rare abnormal chromosome, inv (12)
• Clinical and molecular cytogenetic studies in a case with partial trisomy 12p due to a de novo supernumerary ring chromosome
• Clonality and methylation status of the Epstein-Barr virus (EBV) genomes in in vivo-infected EBV-carrying chronic lymphocytic leukemia (CLL) cell lines
• Cloning and chromosome mapping of the human Mel-18 gene which encodes a DNA-binding protein with a new 'RING-finger' motif
• Coamplification of 12p11 and 12q13 approximately q22 in multiple ring chromosomes in a spindle cell sarcoma resolved by novel multicolor fluorescence in situ hybridization analysis
• Combined morphologic and karyotypic study of 28 myxoid liposarcomas. Implications for a revised morphologic typing, (a report from the CHAMP Group)
• Common variants at 12q15 and 12q24 are associated with infant head circumference
• Comparative genomic hybridization as a tool to define two distinct chromosome 12-derived amplification units in well-differentiated liposarcomas
• Complex composition and co-amplification of SAS and MDM2 in ring and giant rod marker chromosomes in well-differentiated liposarcoma
• Coordinated expression and amplification of the MDM2, CDK4, and HMGI-C genes in atypical lipomatous tumours
• Cytogenetic and comparative genomic hybridization studies of an esophageal giant fibrovascular polyp: a case report
• Cytogenetic and fluorescence in situ hybridization investigation of ring chromosomes characterizing a specific pathologic subgroup of adipose tissue tumors
• Cytogenetic survey of 117 Tunisian patients with de novo myelodysplastic syndrome
• Dedifferentiated liposarcoma
• Dedifferentiated liposarcoma with "homologous" lipoblastic (pleomorphic liposarcoma-like) differentiation: clinicopathologic and molecular analysis of a series suggesting revised diagnostic criteria
• Detection of MDM2 gene amplification or protein expression distinguishes sclerosing mesenteritis and retroperitoneal fibrosis from inflammatory well-differentiated liposarcoma
• Detection of mosaic ring chromosome 12 or 46,XY,r(12) (p13.3q24.33)/46, XY in a 37-year-old male associated with oligospermia but no other apparently phenotypic abnormalities
• Differentially amplified chromosome 12 sequences in low- and high-grade osteosarcoma
• Direct outgrowth of in vivo Epstein-Barr virus (EBV)-infected chronic lymphocytic leukemia (CLL) cells into permanent lines
• Double minute chromosomes harboring MDM2 amplification in a pediatric atypical lipomatous tumor
• Duplication of chromosome segment 12q15-24 is associated with atypical lipomatous tumors: a report of the CHAMP collaborative study group. CHromosomes And MorPhology
• Dysregulation of HMGIC in a uterine lipoleiomyoma with a complex rearrangement including chromosomes 7, 12, and 14
• Epilepsy and electroencephalographic findings in pericentric inversion of chromosome 12
• Failure to validate association between 12p13 variants and ischemic stroke
• Fifty probands with extra structurally abnormal chromosomes characterized by fluorescence in situ hybridization
• Five SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin (SMARC) genes are dispersed in the human genome
• Fluorescence in situ hybridization analyses of hematologic malignancies reveal frequent cytogenetically unrecognized 12p rearrangements
• Fluorescence in situ hybridization for MDM2 gene amplification as a diagnostic tool in lipomatous neoplasms
• Formation of the 12q14-q15 amplicon precedes the development of a well-differentiated liposarcoma arising from a nonchondroid pulmonary hamartoma
• From cytogenetics to cytogenomics of adipose tissue tumors: 2. Malignant adipose tissue tumors
• Genomic profiling of bone and soft tissue tumors with supernumerary ring chromosomes using tiling resolution bacterial artificial chromosome microarrays
• High-resolution genomic mapping reveals consistent amplification of the fibroblast growth factor receptor substrate 2 gene in well-differentiated and dedifferentiated liposarcoma
• HMGA2 and MDM2 expression in lipomatous tumors with partial, low-level amplification of sequences from the long arm of chromosome 12
• Immunohistochemical, cytogenetic, and molecular cytogenetic characterization of both components of a dedifferentiated liposarcoma: implications for histogenesis
• Innovative antimicrobial substances based on uracil S-derivatives
• Involvement of interstitial telomeric sequences in two new cases of mosaicism for autosomal structural rearrangements
• Leiomyoma of uterus in a patient with ring chromosome 12: case presentation and literature review
• Lipomas have characteristic structural chromosomal rearrangements of 12q13-q14
• Liposarcoma: new entities and evolving concepts
• Locus-specific multifluor FISH analysis allows physical characterization of complex chromosome abnormalities in neoplasia
• Low-level chromosome 12 amplification in a primary lipoma of the lung: evidence for a pathogenetic relationship with common adipose tissue tumors
• Mammary analog secretory carcinoma of salivary gland: cytologic diagnosis and differential diagnosis of an unreported entity
• MDM2 amplification in rod-shaped chromosomes provides clues to early stages of circularized gene amplification in liposarcoma
• MDM2 gene amplification correlates with ring chromosome in soft tissue tumors
• Microdeletions involving chromosomes 12 and 22 associated with syndromic Duane retraction syndrome
• Molecular abnormalities in liposarcoma: role of MDM2 and CDK4-containing amplicons at 12q13-22
• Molecular characterisation of a supernumerary ring chromosome in a patient with VATER association
• Molecular cytogenetic anomalies and phenotype alterations in a newly established cell line from Wilms tumor with diffuse anaplasia
• Monosomy 7 and absence of 12q amplification in two cases of spindle cell liposarcomas
• Mosaic ring 12p and total anomalous pulmonary venous return
• Multiple small accessory marker chromosomes from different centromeric origin in a moderately mentally retarded male
• Novel clinical findings in a case of postnatally diagnosed trisomy 12 mosaicism
• Novel regions of chromosomal amplification at 6p21, 5p13, and 12q14 in gastric cancer identified by array comparative genomic hybridization
• Pallister-Killian syndrome caused by mosaicism for a supernumerary ring chromosome 12p
• Patient with three euchromatic supernumerary marker chromosomes derived from chromosomes 1, 12, and 18: characterization and evaluation of the aberrations
• Potential role of regulatory DNA variants in modifying the risk of severe cutaneous reactions induced by aromatic anti-seizure medications
• Pre-B acute lymphoblastic leukemia in a 3-year-old boy with pre-acute myelogenous leukemia myelodysplastic syndrome: cytogenetic evidence of common early progenitor cell ontogeny
• Reciprocal translocation t(3;12)(q27;q13) in lipoma
• Retained heterodisomy for chromosome 12 in atypical lipomatous tumors: implications for ring chromosome formation
• Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13
• Ring chromosome 12
• Ring chromosome 12 and severe oligospermia: a case report
• Ring chromosome 12 resulting from nonrandom telomeric associations with the short arm of chromosome 15 in a cerebellar astrocytoma
• Ring chromosome 12 with inverted microduplication of 12p13.3 involving the Von Willebrand Factor gene associated with cryptogenic stroke in a young adult male
• Ring chromosome 12 with variable phenotypic features: clinical report and review of the literature
• Ring chromosomes and low-grade gene amplification in an atypical lipomatous tumor with minimal nuclear atypia
• Ring chromosomes in parosteal osteosarcoma contain sequences from 12q13-15: a combined cytogenetic and comparative genomic hybridization study
• Ring formation and structural rearrangements of chromosome 1 as secondary changes in uterine leiomyomas with t(12;14)(q14-15;q23-24)
• Selective elimination of amplified CDK4 sequences correlates with spontaneous adipocytic differentiation in liposarcoma
• Similar mechanisms formed ring markers containing chromosome 12 pericentromeric region in two patients with therapy-related acute myeloid leukemia
• Structure of the supernumerary ring and giant rod chromosomes in adipose tissue tumors
• Supernumerary ring chromosome: an etiology for Pallister-Killian syndrome?
• Supernumerary ring chromosomes and nuclear blebs in some low-grade malignant soft tissue tumours: atypical lipomatous tumours and dermatofibrosarcoma protuberans
• Supernumerary ring chromosomes derived from the long arm of chromosome 12 as the primary cytogenetic anomaly in a rare soft tissue chondroma
• Supernumerary ring marker chromosome as a secondary rearrangement in a parapharyngeal lipoma with t(10;12)(q25;q15) as the primary karyotypic abnormality
• The structure and dynamics of ring chromosomes in human neoplastic and non-neoplastic cells
• Uterine leiomyoma cytogenetics
• Well-differentiated and dedifferentiated liposarcomas with prominent myxoid stroma: analysis of 56 cases