Disease: Canavan disease
- A 3D-printed flow-cell for on-grid purification of electron microscopy samples directly from lysate
- A randomized, double-blind trial of triheptanoin for drug-resistant epilepsy in glucose transporter 1 deficiency syndrome
- Ablating the Transporter Sodium-Dependent Dicarboxylate Transporter 3 Prevents Leukodystrophy in Canavan Disease Mice
- ACPA Status Correlates with Differential Immune Profile in Patients with Rheumatoid Arthritis
- Adding 6 months of androgen deprivation therapy to postoperative radiotherapy for prostate cancer: a comparison of short-course versus no androgen deprivation therapy in the RADICALS-HD randomised controlled trial
- Adeno-associated virus-mediated gene therapy in a patient with Canavan disease using dual routes of administration and immune modulation
- Adjuvant Chemotherapy for T4 Non-Small Cell Lung Cancer with Additional Ipsilateral Lung Nodules
- Alcohol Intake as a Risk Factor for Acute Stroke: The INTERSTROKE Study
- Alexander Disease
- An unusual case of a toddler with Canavan disease with frequent intractable seizures: A case report and review of the literature
- Anger or emotional upset and heavy physical exertion as triggers of stroke: the INTERSTROKE study
- Antisense Oligonucleotide Therapy for the Nervous System: From Bench to Bedside with Emphasis on Pediatric Neurology
- Artificial Intelligence in Inflammatory Bowel Disease Endoscopy: Implications for Clinical Trials
- Artificial intelligence in inflammatory bowel disease: implications for clinical practice and future directions
- Aspartic Acid in Health and Disease
- Assessing changes in adolescent girls' and young women's sexual and reproductive health service utilisation following a COVID-19 lockdown in eSwatini
- Association Between Metastatic Pattern and Prognosis in Stage IV Gastric Cancer: Potential for Stage Classification Reform
- Associations of percentage energy intake from total, animal and plant protein with overweight/obesity and underweight among adults in Addis Ababa, Ethiopia
- Astroglial conditional Slc13a3 knockout is therapeutic in murine Canavan leukodystrophy
- Canakinumab for the treatment of autoinflammatory very early onset- inflammatory bowel disease
- Canavan Disease
- Canavan Disease
- Canavan Disease as a Model for Gene Therapy-Mediated Myelin Repair
- Canavan Disease: Clinical and Laboratory Profile from Southern Part of India
- Canavan's spongiform leukodystrophy (Aspartoacylase deficiency) with emphasis on sonographic features in infancy: description of a case report and review of the literature
- Cellular and molecular mechanisms of aspartoacylase and its role in Canavan disease
- Clarifying Optimal Sodium InTake In Cardiovasular and Kidney (COSTICK) Diseases: a study protocol for two randomised controlled trials
- Clinical and genetic analysis of a child with Canavan disease due to compound heterozygous variants of ASPA gene
- Clustering of Juvenile Canavan disease in an Indian community due to population bottleneck and isolation: genomic signatures of a founder event
- Congenital spongiform leukodystrophy in 2 female littermate German shepherd puppies
- Considerations for Colorectal Neoplasia Detection in Inflammatory Bowel Disease Clinical Trials
- Containment of a carbapenem-resistant Acinetobacter baumannii complex outbreak in a COVID-19 intensive care unit
- Cribriform Appearance of White Matter in Canavan Disease Associated with Novel Mutations of <em>ASPA</em> Gene
- Cribriform Appearance of White Matter in Canavan Disease Associated with Novel Mutations of ASPA Gene
- Deep mutational scanning reveals a correlation between degradation and toxicity of thousands of aspartoacylase variants
- Developing a human iPSC-derived three-dimensional myelin spheroid platform for modeling myelin diseases
- Developing Hypoimmunogenic Human iPSC-Derived Oligodendrocyte Progenitor Cells as an Off-The-Shelf Cell Therapy for Myelin Disorders
- Dialysis Facility Profit Status and Early Steps in Kidney Transplantation in the Southeastern United States
- Dietary counselling to reduce moderate sodium intake: effects on cardiovascular and renal biomarkers: primary findings of the COSIP and STICK phase II feasibility randomised controlled trials
- Dual-function AAV gene therapy reverses late-stage Canavan disease pathology in mice
- Duration of androgen deprivation therapy with postoperative radiotherapy for prostate cancer: a comparison of long-course versus short-course androgen deprivation therapy in the RADICALS-HD randomised trial
- Efficacy and Safety of Approximately 3 Years of Continuous Ozanimod in Moderately to Severely Active Ulcerative Colitis: Interim Analysis of the True North Open-label Extension
- Engineering of a critical membrane-anchored enzyme for high solubility and catalytic activity
- Evaluation of a National Quality Improvement Collaborative for Improving Cancer Screening
- Evaluation of gastroesophageal reflux disease and hiatal hernia as risk factors for lobectomy complications
- Feline Spongy Encephalopathy With a Mutation in the <em>ASPA</em> Gene
- Full, Partial, and Modified Permutations of the Mayo Score: Characterizing Clinical and Patient-Reported Outcomes in Ulcerative Colitis Patients
- Functional Abilities of an International Post-Stroke Population: Standard Assessment of Global Everyday Activities (SAGEA) Scale
- Functionally Mature CD1c<sup>+</sup> Dendritic Cells Preferentially Accumulate in the Inflammatory Arthritis Synovium
- Genetic analysis and prenatal diagnosis for a Chinese pedigree affected with Canavan disease
- Genetic testing of leukodystrophies unraveling extensive heterogeneity in a large cohort and report of five common diseases and 38 novel variants
- HIF1α-glycolysis engages activation-induced cell death to drive IFN-γ induction in hypoxic T cells
- High genetic heterogeneity of leukodystrophies in Iranian children: the first report of Iranian Leukodystrophy Registry
- High Throughput Screening Cascade To Identify Human Aspartate <em>N</em>-Acetyltransferase (ANAT) Inhibitors for Canavan Disease
- High Throughput Screening Cascade To Identify Human Aspartate N-Acetyltransferase (ANAT) Inhibitors for Canavan Disease
- Homozygous Paternally Inherited ASPA Variant in a Patient with Canavan Disease
- Household-level double burden of malnutrition in Ethiopia: a comparison of Addis Ababa and the rural district of Kersa
- Human induced pluripotent stem cell line (SDQLCHi064-A) derived from a patient with Canavan disease carrying c.556_559dup GTTC and c.919delA mutations in the ASPA gene
- Hypertension and Cognitive Impairment: A Review of Mechanisms and Key Concepts
- Identification of potential pharmacological chaperones that selectively stabilize mutated Aspartoacylases in Canavan disease
- Immunosuppressed patients are at increased risk of local recurrence, metastasis, and disease specific death from cutaneous squamous cell carcinoma
- Impact of an electronic smart order-set for diagnostic stewardship of Clostridiodes difficile infection (CDI) in a community healthcare system in South Florida
- Knowledge of disease, diagnosis, adherence and impact of research in an Irish cohort of patients with inflammatory arthritis
- Leukodystrophy Imaging: Insights for Diagnostic Dilemmas
- Life expectancy and agricultural environmental impacts in Addis Ababa can be improved through optimized plant and animal protein consumption
- LncRNA CRNDE promotes hepatoma cell proliferation by regulating the metabolic reprogramming of M2 macrophages via ERK pathway
- Loss of balance between protective and pro-inflammatory synovial tissue T-cell polyfunctionality predates clinical onset of rheumatoid arthritis
- Mandibular Measurements at the 20-Week Anatomy Ultrasound as a Prenatal Diagnostic Predictor of Pierre Robin Sequence
- Mapping the degradation pathway of a disease-linked aspartoacylase variant
- Metabolites as drivers and targets in rheumatoid arthritis
- Mycoplasma Mucositis
- Mycoplasma Mucositis
- Mycoplasma pneumoniae–Induced Rash and Mucositis (MIRM)
- Myelin lesion in the aspartoacylase (Aspa) knockout rat, an animal model for Canavan disease
- N-acetyl-aspartate metabolism at the interface of cancer, immunity, and neurodegeneration
- NAAG synthetase deficiency has only low influence on pathogenesis in a Canavan disease mouse model
- Nonregional Lymph Nodes as the Only Metastatic Site in Stage IV Esophageal Cancer
- On Clustering of Juvenile Canavan disease in an Indian community due to population bottleneck and isolation: Genomic signatures of a founder event
- Pathological Bergmann glia alterations and disrupted calcium dynamics in ataxic Canavan disease mice
- Preclinical biodistribution, tropism, and efficacy of oligotropic AAV/Olig001 in a mouse model of congenital white matter disease
- Quantification of N-acetyl-l-aspartate in dried blood spots: A simple and fast LC-MS/MS neonatal screening method for the diagnosis of Canavan disease
- Quantifying the Association between Pump Use and Breastfeeding Duration
- Racial/ethnic, socioeconomic, and geographic survival disparities in adolescents and young adults with primary central nervous system tumors
- Recent Advancements in the Diagnosis and Treatment of Leukodystrophies
- Renal Impairment and Risk of Acute Stroke: The INTERSTROKE Study
- Renewal of oligodendrocyte lineage reverses dysmyelination and CNS neurodegeneration through corrected N-acetylaspartate metabolism
- Retracing the tracks for SIAD: hyponatraemia due to post-traumatic brain injury hypopituitarism
- Rivaroxaban versus aspirin on functional and cognitive outcomes after embolic stroke of undetermined source: NAVIGATE ESUS trial
- Ruxolitinib: Targeted Approach for Treatment of Autoinflammatory Very Early Onset Inflammatory Bowel Disease
- Selective screening for inborn errors of metabolism by tandem mass spectrometry at Sohag University Hospital, Egypt
- Systemic Anticancer Therapy and Overall Survival in Patients With Very Advanced Solid Tumors
- Tea and coffee consumption and risk of acute stroke: The INTERSTROKE Study
- The full spectrum of MRI findings in 18 patients with Canavan disease: new insights into the areas of selective susceptibility
- The future of public health doctoral education in Africa: transforming higher education institutions to enhance research and practice
- The natural history of Canavan disease: 23 new cases and comparison with patients from literature
- The pathogenesis of, and pharmacological treatment for, Canavan disease
- The PD-1:PD-L1 axis in Inflammatory Arthritis
- Therapeutic development for Canavan disease using patient iPSCs introduced with the wild-type <em>ASPA</em> gene
- Therapeutic development for Canavan disease using patient iPSCs introduced with the wild-type ASPA gene
- Virus-Based Biological Systems as Next-Generation Carriers for the Therapy of Central Nervous System Diseases