Disease: Broad beta disease
- 4,4'-methylenediphenol reduces Abeta-induced toxicity in a Caenorhabditis elegans model of Alzheimer's disease
- A broadly neutralizing human monoclonal antibody generated from transgenic mice immunized with HCMV particles limits virus infection and proliferation
- A comprehensive bibliometric analysis of global research on the role of acrolein in Alzheimer's disease pathogenesis: involvement of amyloid-beta
- A Japanese Woman with Polygenic Familial Hypercholesteremia Who Exhibited Trivial Atherosclerosis
- A novel high-titer, bifunctional lentiviral vector for autologous hematopoietic stem cell gene therapy of sickle cell disease
- A randomised, parallel-group, double-blind, placebo-controlled phase 3 study to Determine the effectiveness of the type I interferon receptor antibody, Anifrolumab, In SYstemic sclerosis: DAISY study design and rationale
- A VHH single-domain platform enabling discovery and development of monospecific antibodies and modular neutralizing bispecifics against SARS-CoV-2 variants
- Adenosine A2A Receptor Antagonist Sch58261 Improves the Cognitive Function in Alzheimer's Disease Model Mice Through Activation of Nrf2 via an Autophagy-Dependent Pathway
- Advancing molecular modeling and reverse vaccinology in broad-spectrum yellow fever virus vaccine development
- Amyloid beta accelerates age-related proteome-wide protein insolubility
- Anthracycline-induced cardiotoxicity: An overview from cellular structural perspective
- Anti-Inflammatory Therapy in Coronary Artery Disease: Where Do We Stand?
- Antimicrobial Resistance Genes in Respiratory Bacteria from Weaned Dairy Heifers
- Antimicrobial Susceptibility Profiles of <em>Klebsiella pneumoniae</em> Strains Collected from Clinical Samples in a Hospital in Southern Italy
- Apolipoprotein C-III, familial chylomicronemia syndrome, and olezarsen
- Assessment of Clinician-Reported Outcome Measures for Alopecia Areata: A Systematic Scoping Review
- Autonomous circadian rhythms in the human hepatocyte regulate hepatic drug metabolism and inflammatory responses
- Aβ Oligomer Dissociation Is Catalyzed by Fibril Surfaces
- Behaviour Hallmarks in Alzheimer's Disease 5xFAD Mouse Model
- beta-d-N(4)-hydroxycytidine, a metabolite of molnupiravir, exhibits in vitro antiviral activity against rabies virus
- Biochemical and molecular determinants of the subclinical inflammatory mechanisms in Rett syndrome
- Biocontrol of <em>Fusarium</em> head blight in rice using <em>Bacillus velezensis</em> JCK-7158
- Broad protection against invasive fungal disease from a nanobody targeting the active site of fungal b-1,3-glucanosyltransferases
- Broad Protection against Invasive Fungal Disease from a Nanobody Targeting the Active Site of Fungal beta-1,3-Glucanosyltransferases
- Calcium(II)-Mediated Three-Component Selenylation of gem-Difluoroalkenes: Access to alpha,alpha-Difluoroalkyl-beta-selenides
- Cerebrospinal fluid reference proteins increase accuracy and interpretability of biomarkers for brain diseases
- Chronic osteoarthritis caused by <em>Propionibacterium australiense</em> infection in a captive sand gazelle
- Clostridial Myonecrosis: A Comprehensive Review of Toxin Pathophysiology and Management Strategies
- Comparative immunogenicity of monovalent and bivalent adenovirus vaccines carrying spikes of early and late SARS-CoV-2 variants
- Consensus document on diagnosis and management of familial hypercholesterolemia from the Italian Society for the Study of Atherosclerosis (SISA)
- CryoET of beta-amyloid and tau within postmortem Alzheimer's disease brain
- Deconvolution of polygenic risk score in single cells unravels cellular and molecular heterogeneity of complex human diseases
- Development and Validation of a Novel Placental DNA Methylation Biomarker of Maternal Smoking during Pregnancy in the ECHO Program
- Dipeptidyl peptidase 4 interacts with porcine coronavirus PHEV spikes and mediates host range expansion
- Dual α-globin and truncated EPO receptor knockin restores hemoglobin production in α-thalassemia-derived red blood cells
- Effects of household concrete floors on maternal and child health - the CRADLE trial: a randomised controlled trial protocol
- Efficacy of a stable broadly protective subunit vaccine platform against SARS-CoV-2 variants of concern
- Endoplasmic reticulum stress in pancreatic beta-cell dysfunction: The potential therapeutic role of dietary flavonoids
- Enhanced Omicron Variant Neutralization by a Human Antibody Tailored to Wild-Type and Delta-Variant SARS-CoV-2 RBDs
- Etiology and emerging treatments for familial chylomicronemia syndrome
- Evaluation of Patients with Painful Ophthalmoplegia for Benign and Secondary Etiologies
- Evidence-based data support prevention strategies to Hymenoptera venom anaphylaxis
- Evinacumab in homozygous familial hypercholesterolaemia: long-term safety and efficacy
- Exploration of the mechanism of Traditional Chinese Medicine for anxiety and depression in patients with diarrheal irritable bowel syndrome based on network pharmacology and meta-analysis
- Exploring Dimethylsulfoniopropionate as a potential treatment for Alzheimer's disease: A study using the 3 Tg-AD mouse model
- First report of <em>Neopestalotiopsis clavispora</em> Causing guava scab in China
- Fluid Biomarkers in Individuals at Risk for Genetic Prion Disease up to Disease Conversion
- Frontiers and hotspots evolution in anti-inflammatory studies for Alzheimer's disease
- Gamma-Tubulin 1 (TUBG1) Mutation-Associated Lissencephaly and Microcephaly in an Indian Child: A Rare Case
- Generation and Characterization of a Novel Knockin Mouse Model Expressing PSEN1 D385A: Implications for Investigating Herbal Drug Effects in γ-Secretase Activity
- GJB3: a comprehensive biomarker in pan-cancer prognosis and immunotherapy prediction
- Glycan-shielded homodimer structure and dynamical features of the canine distemper virus hemagglutinin relevant for viral entry and efficient vaccination
- GSK3-Driven Modulation of Inflammation and Tissue Integrity in the Animal Model
- High expression of anti-beta2 glycoprotein I (beta2GPI) autoantibody exacerbates inflammation and immune dysfunction in connective tissue disease
- Highly tunable bimane-based fluorescent probes: design, synthesis, and application as a selective amyloid binding dye
- Importin-7-dependent nuclear translocation of the Flavivirus core protein is required for infectious virus production
- Improving the Detection of Potential Cases of Familial Hypercholesterolemia: Could Machine Learning Be Part of the Solution?
- Increased Genetic Risk for beta-Cell Failure Is Associated With beta-Cell Function Decline in People With Prediabetes
- Komrower Memorial Lecture 2023. Molecular basis of phenotype expression in homocystinuria: Where are we 30 years later?
- Long-term sex differences in atherosclerotic cardiovascular disease in individuals with heterozygous familial hypercholesterolaemia in Spain: a study using data from SAFEHEART, a nationwide, multicentre, prospective cohort study
- Loss of <em>RREB1</em> reduces adipogenesis and improves insulin sensitivity in mouse and human adipocytes
- LPA3 agonist-producing Bacillus velezensis ADS024 is efficacious in multiple neuroinflammatory disease models
- MetALD: Does it require a different therapeutic option?
- Microbiome and Metabolite Analysis Insight into the Potential of Shrimp Head Hydrolysate to Alleviate Depression-like Behaviour in Growth-Period Mice Exposed to Chronic Stress
- Microbiota restoration therapies for recurrent <em>Clostridioides difficile</em> infection reach an important new milestone
- Modeling epithelial homeostasis and perturbation in three-dimensional human esophageal organoids
- Naringin: Cardioprotective properties and safety profile in diabetes treatment
- Naringin: Cardioprotective properties and safety profile in the treatment of diabetes
- National and Regional Trends in the Prevalence of Hypertension in South Korea Amid the Pandemic, 2009-2022: Nationwide Study of Over 3 Million Individuals
- National prevalence of atopic dermatitis in Korean adolescents from 2009 to 2022
- National trends in counseling for stress and depression and COVID-19 pandemic-related factors among adults, 2009-2022: A nationwide study in South Korea: Stress, depression, and pandemic
- National trends in sexual intercourse and usage of contraception among Korean adolescents
- Obicetrapib on top of maximally tolerated lipid-modifying therapies in participants with or at high risk for atherosclerotic cardiovascular disease: rationale and designs of BROADWAY and BROOKLYN
- Plasma Proteomics of Exercise Blood Pressure and Incident Hypertension
- Plasma pTau217 predicts continuous brain amyloid levels in preclinical and early Alzheimer's disease
- Poly(beta-aminoester) Physicochemical Properties Govern the Delivery of siRNA from Electrostatically Assembled Coatings
- Predicting type 2 diabetes via machine learning integration of multiple omics from human pancreatic islets
- Preparation and Characterization of Zn(II)-Stabilized Aβ<sub>42</sub> Oligomers
- Prevalence and Antimicrobial Resistance Diversity of <em>Salmonella</em> Isolates in Jiaxing City, China
- Prevalence in Potato of '<em>Candidatus</em> Arsenophonus Phytopathogenicus' and '<em>Candidatus</em> Phytoplasma Solani' and Their Transmission via Adult <em>Pentastiridius leporinus</em>
- Primary SARS-CoV-2 variant of concern infections elicit broad antibody Fc-mediated effector functions and memory B cell responses
- Protocol for quantifying LC3B FRET biosensor activity in living cells using a broad-to-sensitive data analysis pipeline
- RATA: A novel class A carbapenemase with broad geographic distribution and potential for global spread
- Relative inhibitory activities of the broad-spectrum beta-lactamase inhibitor xeruborbactam in comparison with taniborbactam against metallo-beta-lactamases produced in Escherichia coli and Pseudomonas aeruginosa
- ROCK Inhibitor Fasudil Attenuates Neuroinflammation and Associated Metabolic Dysregulation in the Tau Transgenic Mouse Model of Alzheimer's Disease
- Safety, tolerability and pharmacokinetics of ASC10, a novel oral double prodrug of a broad-spectrum antiviral agent, beta-d-N4-hydroxycytidine: results from a randomized, double-blind, placebo-controlled phase 1 study in Chinese healthy subjects
- SARS-CoV-2 recombinant spike ferritin nanoparticle vaccine adjuvanted with Army Liposome Formulation containing monophosphoryl lipid A and QS-21: a phase 1, randomised, double-blind, placebo-controlled, first-in-human clinical trial
- Secoisolariciresinol diglucoside attenuates neuroinflammation and cognitive impairment in female Alzheimer's disease mice via modulating gut microbiota metabolism and GPER/CREB/BDNF pathway
- Sex differences and immune correlates of Long COVID development, persistence, and resolution
- Signaling pathways activated and regulated by stem cell-derived exosome therapy
- Strategies for measuring concentrations and forms of amyloid-beta peptides
- Targeting Myeloid Differentiation Primary Response Protein 88 (MyD88) and Galectin-3 to Develop Broad-Spectrum Host-Mediated Therapeutics against SARS-CoV-2
- The "toxic window" of amoxicillin exposure during pregnancy on long bone development in fetal mice
- The Activin Branch Ligand Daw Regulates the <em>Drosophila melanogaster</em> Immune Response and Lipid Metabolism against the <em>Heterorhabditis bacteriophora</em> Serine Carboxypeptidase
- The burden of antibiotic resistance of the main microorganisms causing infections in humans - review of the literature
- The impact of chelating compounds on Cu(2+), Fe(2+)/(3+), and Zn(2+) ions in Alzheimer's disease treatment
- The Role of Imatinib in Pediatric Type 1 Diabetes
- Three major effects of APOE<sup>ε4</sup> on Aβ immunotherapy induced ARIA
- Unraveling Verapamil's Multidimensional Role in Diabetes Therapy: From beta-Cell Regeneration to Cholecystokinin Induction in Zebrafish and MIN6 Cell-Line Models
- Virulent-MDR-ESBL E. coli and Klebsiella pneumoniae report from North Sinai calves diarrhea and in vitro antimicrobial by Moringa oleifera