Disease: Bile Acid Synthesis
- A Current Understanding of FXR in NAFLD: The multifaceted regulatory role of FXR and novel lead discovery for drug development
- A high-dose of ursodeoxycholic acid treatment alleviates liver inflammation by remodeling gut microbiota and bile acid profile in a mouse model of non-alcoholic steatohepatitis
- A New <em>Bacillus velezensis</em> Strain CML532 Improves Chicken Growth Performance and Reduces Intestinal <em>Clostridium perfringens</em> Colonization
- A prognostic model established using bile acid genes to predict the immunity and survival of patients with gastrointestinal cancer
- Age-Dependent Differences in Postprandial Bile-Acid Metabolism and the Role of the Gut Microbiome
- Alteration of Gut Microbiota Composition in the Progression of Liver Damage in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
- Analysis of Plasma Metabolic Profile in Children with Transfusion-Dependent Thalassemia
- Analysis of the potential regulatory mechanisms of female and latent genital tuberculosis affecting ovarian reserve function using untargeted metabolomics
- Anthocyanins from Lycium ruthenicum Murray attenuates high-fat diet-induced hypercholesterolemia in ApoE(-/-) mice are related to the modulation of gut microbiota and the ratio of conjugated to unconjugated bile acids in fecal bile acid profile
- Anti-obesity potentiality of Lactiplantibacillus plantarum E2_MCCKT isolated from a fermented beverage, haria: a high fat diet-induced obese mice model study
- Bile Acid Diarrhea
- Bile acid metabolism and signaling in health and disease: molecular mechanisms and therapeutic targets
- Bile acid metabolism is altered in learning and memory impairment induced by chronic lead exposure
- Bile Acid-Targeted Hyaluronic Acid Nanoparticles for Enhanced Oral Absorption of Deferoxamine
- Bile conjugation and its effect on in vitro lipolysis of emulsions
- Bioinformatics and system biology approaches to determine the connection of SARS-CoV-2 infection and intrahepatic cholangiocarcinoma
- Biological evaluation of sulfonate and sulfate analogues of lithocholic acid: A bioisosterism-guided approach towards the discovery of potential sialyltransferase inhibitors for antimetastatic study
- Caffeic acid combined with arabinoxylan or beta-glucan attenuates diet-induced obesity in mice via modulation of gut microbiota and metabolites
- Cardiometabolic Differences in People Living with HIV Receiving Integrase Strand Transfer Inhibitors Compared to Non-nucleoside Reverse Transcriptase Inhibitors: Implications for Current ART Strategies
- Cerebrotendinous xanthomatosis with tremor as the main manifestation: A case report
- Cereus jamacaru DC. (mandacaru) fruit as a source of lactic acid bacteria with in vitro probiotic-related characteristics and its protective effects on Pediococcus pentosaceus during lyophilization and refrigeration storage
- Characterization of the gut microbiota and fecal and blood metabolomes under various factors in urban children from Northwest China
- Chemoproteomic profiling of substrate specificity in gut microbiota-associated bile salt hydrolases
- Cholemic Nephropathy: Role in Acute Kidney Injury in Cholestasis and Cirrhosis
- Comprehensive clinical and genetic analyses of circulating bile acids and their associations with diabetes and its indices
- Comprehensive Multi-Omic Evaluation of the Microbiota and Metabolites in the Colons of Diverse Swine Breeds
- Dan-shen Yin promotes bile acid metabolism and excretion to prevent atherosclerosis via activating FXR/BSEP signaling pathway
- Development of a Novel, Potent, and Selective Sialyltransferase Inhibitor for Suppressing Cancer Metastasis
- Development of porcine skeletal muscle extracellular matrix-derived hydrogels with improved properties and low immunogenicity
- Diet changes due to urbanization in South Africa are linked to microbiome and metabolome signatures of Westernization and colorectal cancer
- Dietary fat supplementation relieves cold temperature-induced energy stress through AMPK-mediated mitochondrial homeostasis in pigs
- Discovery of PXR agonists from Hypericum japonicum: A class of novel nonaromatic acylphloroglucinol-terpenoid adducts
- Dynamic Changes of the Gut Microbiota and Its Functional Metagenomic Potential during the Development of Non-Small Cell Lung Cancer
- Effects of bile acid metabolism on intestinal health of livestock and poultry
- Exploring Advanced Therapies for Primary Biliary Cholangitis: Insights from the Gut Microbiota-Bile Acid-Immunity Network
- Exploring Bile-Acid Changes and Microflora Profiles in Chicken Fatty Liver Disease Model
- Exploring the immune-inflammatory mechanism of Maxing Shigan Decoction in treating influenza virus A-induced pneumonia based on an integrated strategy of single-cell transcriptomics and systems biology
- Expression of bile acid receptors and transporters along the intestine of patients with type 2 diabetes and controls
- Extrusion and chlorogenic acid treatment increase the ordered structure and resistant starch levels in rice starch with amelioration of gut lipid metabolism in obese rats
- Generation and characterization of mature hepatocyte organoids for liver metabolic studies
- Genetically and clinically confirmed atypical cerebrotendinous xanthomatosis with normal cholestanol and marked elevations of bile acid precursors and bile alcohols
- Gut microbiome composition and metabolic activity in women with diverticulitis
- Gut symbionts alleviate MASH through a secondary bile acid biosynthetic pathway
- High temperature and humidity in the environment disrupt bile acid metabolism, the gut microbiome, and GLP-1 secretion in mice
- Hypoglycemic Activity of Rice Resistant-Starch Metabolites: A Mechanistic Network Pharmacology and In Vitro Approach
- Impacts of liver macrophages, gut microbiota, and bile acid metabolism on the differences in iHFC diet-induced MASH progression between TSNO and TSOD mice
- Incorporating Lycium barbarum residue in diet boosts survival, growth, and liver health in juvenile grass carp (Ctenopharyngodon idellus)
- Increased hepatoprotective effects of the novel farnesoid X receptor agonist INT-787 versus obeticholic acid in a mouse model of nonalcoholic steatohepatitis
- Increased intestinal bile acid absorption contributes to age-related cognitive impairment
- Induction of hepatic CYP3A4 expression by cholesterol and cholic acid: Alterations of gene expression, microsomal activity, and pharmacokinetics
- Inhibition of fatty acid uptake by TGR5 prevents diabetic cardiomyopathy
- Integrated physiological, intestinal microbiota, and metabolomic responses of adult zebrafish (Danio rerio) to subacute exposure to antimony at environmentally relevant concentrations
- Intestinal FGF15 regulates bile acid and cholesterol metabolism but not glucose and energy balance
- Investigation of Effects of Novel <em>Bifidobacterium longum</em> ssp. <em>longum</em> on Gastrointestinal Microbiota and Blood Serum Parameters in a Conventional Mouse Model
- Investigational farnesoid X receptor agonists for the treatment of primary biliary cholangitis
- Isolation of mucosa-associated microbiota dysbiosis in the ascending colon in hepatitis C virus post-sustained virologic response cirrhotic patients
- Kidney involvement in Wilson's disease: a review of the literature
- Limosilactobacillus reuteri HCS02-001 Attenuates Hyperuricemia through Gut Microbiota-Dependent Regulation of Uric Acid Biosynthesis and Excretion
- Ling-Gui-Zhu-Gan decoction ameliorates nonalcoholic fatty liver disease via modulating the gut microbiota
- Metabolome-microbiome insights into therapeutic impact of 8-O-acetylharpagide against breast cancer in a murine model
- Metabolomics-driven discovery of therapeutic targets for cancer cachexia
- Microbial Fermentation Enhances the Effect of Black Tea on Hyperlipidemia by Mediating Bile Acid Metabolism and Remodeling Intestinal Microbes
- Mineral crude drug mirabilite (Mangxiao) inhibits the occurrence of colorectal cancer by regulating the Lactobacillus-bile acid-intestinal farnesoid X receptor axis based on multiomics integration analysis
- Molecular insights into experimental models and therapeutics for cholestasis
- Molecular Modeling, Synthesis, and Antihyperglycemic Activity of the New Benzimidazole Derivatives - Imidazoline Receptor Agonists
- Multi-omics analysis identifies sex-specific hepatic protein-metabolite networks in yellow catfish (Pelteobagrus fulvidraco) exposed to chronic hypoxia
- Multi-omics analysis reveals leucine deprivation promotes bile acid synthesis by upregulating hepatic CYP7A1 and intestinal Turicibacter sanguinis in mice
- Multiomics analysis investigating the impact of a high-fat diet in female Sprague-Dawley rats: alterations in plasma, intestinal metabolism, and microbial composition
- Navigating cholestasis: identifying inborn errors of bile acid metabolism for precision diagnosis
- Novel Synergistic Probiotic Intervention: Transcriptomic and Metabolomic Analysis Reveals Ameliorative Effects on Immunity, Gut Barrier, and Metabolism of Mice during Salmonella typhimurium Infection
- Ovary metabolome and cecal microbiota changes in aged laying hens supplemented with vitamin E
- Potential probiotic characteristics and genomic analysis of a new folate-producing lactic acid bacteria Lactiplantibacillus plantarum ZFM55
- Protective Mechanism of <em>Eurotium amstelodami</em> from Fuzhuan Brick Tea against Colitis and Gut-Derived Liver Injury Induced by Dextran Sulfate Sodium in C57BL/6 Mice
- Recipient microbiome-related features predicting metabolic improvement following fecal microbiota transplantation in adults with severe obesity and metabolic syndrome: a secondary analysis of a phase 2 clinical trial
- Review: Mechanism of herbivores synergistically metabolizing toxic plants through liver and intestinal microbiota
- Risk of cancer in patients with bile acid diarrhoea: a Danish nationwide matched cohort study
- Role of the microbiota-gut-heart axis between bile acids and cardiovascular disease
- Screening for potential warning biomarkers in cows with ketosis based on host-microbiota co-metabolism analysis
- Sedanolide alleviates DSS-induced colitis by modulating the intestinal FXR-SMPD3 pathway in mice
- Short-term treatment with cholestyramine increases long-acting anticoagulant rodenticide clearance from rabbits without affecting plasma vitamin K1 levels nor blood coagulation
- Sodium oligomannate's amelioration of reproductive and metabolic phenotypes in a letrozole-induced PCOS-like mouse model depends on the gut microbiome
- Spatio-temporal analysis of toxigenic genes expression in the growing Bufo gargarizans based on RNA sequencing data
- Supplementation of Silymarin Alone or in Combination with Salvianolic Acids B and Puerarin Regulates Gut Microbiota and Its Metabolism to Improve High-Fat Diet-Induced NAFLD in Mice
- Tauroursodeoxycholic Acid Mitigates Oxidative Stress and Promotes Differentiation in High Salt-Stimulated Osteoblasts via NOX1 Mediated by PGC-1alpha
- The contribution of small heterodimer partner to the occurrence and progression of cholestatic liver injury
- The Effect of Coenzyme Q10 Supplementation on Bile Acid Metabolism: Insights from Network Pharmacology, Molecular Docking, and Experimental Validation
- The Increased Dissolution and Oral Absorption of Itraconazole by Nanocrystals with an Endogenous Small-Molecule Surfactant as a Stabilizer
- The influence of simulated weightlessness on the composition and function of gut microbiota and bile acid metabolism products
- The nonvesicular sterol transporter Aster-C plays a minor role in whole body cholesterol balance
- The role of bile acids in human aging
- The role of Ca<sup>2+</sup> signalling and InsP3R in the pathogenesis of intrahepatic cholestasis of pregnancy
- The Supplementation of Berberine in High-Carbohydrate Diets Improves Glucose Metabolism of Tilapia (Oreochromis niloticus) via Transcriptome, Bile Acid Synthesis Gene Expression and Intestinal Flora
- Tong-Xie-Yao-Fang strengthens intestinal feedback control of bile acid synthesis to ameliorate irritable bowel syndrome by enhancing bile salt hydrolase-expressing microbiota
- Trimethylamine N-oxide ameliorates hepatic damage including reduction of hepatic bile acids and cholesterol in Fxr-null mice
- Uncovering the Effect of SARS-CoV-2 on Liver Metabolism via Genome-Scale Metabolic Modeling for Reprogramming and Therapeutic Strategies
- Update on the development of TGR5 agonists for human diseases
- UPLC-Triple-TOF-MS-based serum metabonomic revealed the alleviating effect of QingYan Formula on perimenopausal syndrome rats
- Urinary metabolomic profiling of a cohort of Colombian patients with systemic lupus erythematosus
- Ursodeoxycholic acid loaded dual-modified graphene oxide nanocomposite alleviates cholestatic liver injury through inhibiting hepatocyte apoptosis
- Vitamin B6 ameliorates acute pancreatitis by suppressing the caspase3 signaling pathway