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• A methionine-choline-deficient diet induces nonalcoholic steatohepatitis and alters the lipidome, metabolome, and gut microbiome profile in the C57BL/6J mouse
• A systematic review of the gut microbiome, metabolites, and multi-omics biomarkers across the colorectal cancer care continuum
• Age-related sarcopenia and altered gut microbiota: A systematic review
• Alterations in bile acid kinetics after bariatric surgery in patients with obesity with or without type 2 diabetes
• An insoluble cellulose nanofiber with robust expansion capacity protects against obesity
• Analysis of metagenome and metabolome disclosed the mechanisms of Dendrobium officinale polysaccharide on DSS-induced ulcerative colitis-affected mice
• Antioxidant and cholesterol regulatory effect of flavonoid-rich silk sericin
• Autophagy-mediated ferroptosis is involved in development of severe acute pancreatitis
• BAR502/fibrate conjugates: synthesis, biological evaluation and metabolic profile
• Barcoded overexpression screens in gut Bacteroidales identify genes with roles in carbon utilization and stress resistance
• Bile acid diarrhoea and metabolic changes after cholecystectomy: a prospective case-control study
• Bile acid metabolism modulates intestinal immunity involved in ulcerative colitis progression
• Bile acids attenuate hepatic inflammation during ischemia/reperfusion injury
• Bile salt integrated cerasomes: A potential nanocarrier for enhancement of the oral bioavailability of idarubicin hydrochloride
• Biliary atresia: the role of gut microbiome, and microbial metabolites
• Both middle and large envelope proteins can mediate neutralization of hepatitis B virus infectivity by anti-preS2 antibodies: escape by naturally occurring preS2 deletions
• Caffeic acid modulates intestinal microbiota, alleviates inflammatory response, and enhances barrier function in a piglet model challenged with lipopolysaccharide
• Changes in the Bile Acid Pool and Timing of Female Puberty: Potential Novel Role of Hypothalamic TGR5
• Characteristics and function of the gut microbiota in patients with IgA nephropathy via metagenomic sequencing technology
• Chemical chaperones to the rescue of Alport syndrome?
• Cholelithiasis, Gut Microbiota and Bile Acids after Bariatric Surgery-Can Cholelithiasis Be Prevented by Modulating the Microbiota? A Literature Review
• Circadian Rhythms, the Gut Microbiome, and Metabolic Disorders
• Clostridioides difficile colonization is not mediated by bile salts and requires Stickland fermentation of proline in an in vitro model of infection
• Clostridium septicum manifests a bile salt germinant response mediated by Clostridioides difficile csp gene orthologs
• Comment on Yang et al. Bile Acid Diarrhea: From Molecular Mechanisms to Clinical Diagnosis and Treatment in the Era of Precision Medicine. Int. J. Mol. Sci. 2024, 25, 1544
• Comparison of fibroblast growth factor 19 concentrations between dogs with and without gallbladder mucoceles
• Computational study of novel natural agonists targeting farnesoid X receptor
• Core biomarkers analysis benefit for diagnosis on human intrahepatic cholestasis of pregnancy
• Development and validation of a novel 7α-hydroxy-4-cholesten-3-one (C4) liquid chromatography tandem mass spectrometry method and its utility to assess pre-analytical stability
• Dietary bile acids supplementation decreases hepatic fat deposition with the involvement of altered gut microbiota and liver bile acids profile in broiler chickens
• Distinctive duodenal microbiomes and bile acid profiles in duodenal tumor patients revealed by prospective observational study
• Dynamic pattern of postprandial bile acids in paediatric non-alcoholic fatty liver disease
• Dysregulated bile acid homeostasis: unveiling its role in metabolic diseases
• Ethanol Extract of Propolis Attenuates Liver Lipid Metabolism Disorder in High-Fat Diet-Fed SAMP8 Mice
• Exploring the role of a novel postbiotic bile acid: Interplay with gut microbiota, modulation of the farnesoid X receptor, and prospects for clinical translation
• Exposure of Ldlr-/- Mice to a PFAS Mixture and Outcomes Related to Circulating Lipids, Bile Acid Excretion, and the Intestinal Transporter ASBT
• Exposure of Polycyclic Aromatic Hydrocarbons (PAHs) and Crude Oil to Atlantic Haddock (Melanogrammus aeglefinus): A Unique Snapshot of the Mercapturic Acid Pathway
• FGL2 improves experimental colitis related to gut microbiota structure and bile acid metabolism by regulating macrophage autophagy and apoptosis
• Fibroblast Growth Factors in Cardiovascular Disease
• Fluoride induces hepatointestinal damage and vitamin B₂ mitigation by regulating IL-17A and Bifidobacterium in ileum
• Follow-up after urinary diversion
• FXR Antagonist FLG249 Lowers Hepatic Triacylglycerol and Serum Cholesterol Level in High-Fat Diet-Induced Obese Mice
• Gut microbial changes associated with obesity in youth with type 1 diabetes: a Pilot Study
• Gut microbiota-brain bile acid axis orchestrates aging-related neuroinflammation and behavior impairment in mice
• Hepatic Galpha13 ablation shifts region-specific colonic inflammatory status by modulating the bile acid synthetic pathway in mice
• Human genetic variation determines 24-hour rhythmic gene expression and disease risk
• Human Gut Microbiota in Cardiovascular Disease
• Immunology of bile acids regulated receptors
• Impaired intestinal FXR signaling is involved in aberrant stem cell function leading to intestinal failure-associated liver disease in pediatric patients with short bowel syndrome
• Influence of Varied Dietary Cholesterol Levels on Lipid Metabolism in Hamsters
• Integrating 16S rRNA Sequencing and LC-MS-Based Metabolomics to Evaluate the Effects of Dietary Crude Protein on Ruminal Morphology, Fermentation Parameter and Digestive Enzyme Activity in Tibetan Sheep
• Integrating serum pharmacochemistry, network pharmacology and untargeted metabolomics strategies to reveal the material basis and mechanism of action of Feining keli in the treatment of chronic bronchitis
• Isoastragaloside I attenuates cholestatic liver diseases by ameliorating liver injury, regulating bile acid metabolism and restoring intestinal barrier
• Konjac supplementation can alleviate obesity induced by high-fat diet in mice by modulating gut microbiota and its metabolites
• Landscapes of maternal and neonatal gut microbiome and plasma metabolome signatures and their interaction in gestational diabetes mellitus
• Large Scale Genomic Investigation of Pediatric Cholestasis Reveals a Novel Hepatorenal Ciliopathy Caused by PSKH1 Mutations
• Lipid-Lowering Medications for Managing Dyslipidemia: A Narrative Review
• Loss of PPARα function promotes epigenetic dysregulation of lipid homeostasis driving ferroptosis and pyroptosis lipotoxicity in metabolic dysfunction associated Steatotic liver disease (MASLD)
• Machine learning-causal inference based on multi-omics data reveals the association of altered gut bacteria and bile acid metabolism with neonatal jaundice
• Maternal antibiotic prophylaxis during cesarean section has a limited impact on the infant gut microbiome
• Metabolic reprogramming of corn oligopeptide in regulating sodium nitrite-induced canine hepatocyte injury via TGF/NF-κB signaling pathways and aminoacyl-tRNA biosynthesis
• Metabolomic analysis revealed the inflammatory and oxidative stress regulation in response to Vibrio infection in Plectropomus leopardus
• Metabolomic and sphingolipidomic profiling of human hepatoma cells exposed to widely used pharmaceuticals
• Metabolomic profiling analysis reveals the benefits of ginseng berry intake on mitochondrial function and glucose metabolism in the liver of obese mice
• Metabolomics analysis of patients with Schistosoma japonicum infection based on UPLC-MS method
• Metabolomics and network pharmacology exploration of the effects of bile acids on carotid atherosclerosis and potential underlying mechanisms
• Metabolomics and serum pharmacochemistry combined with network pharmacology uncover the potential effective ingredients and mechanisms of Yin-Chen-Si-Ni Decoction treating ANIT-induced cholestatic liver injury
• Metabolomics Unveils Disrupted Pathways in Parkinson's Disease: Toward Biomarker-Based Diagnosis
• Modified Gegen Qinlian Decoction modulated the gut microbiome and bile acid metabolism and restored the function of goblet cells in a mouse model of ulcerative colitis
• Modulation of Lipid Digestion by Nanoarchitectonics of Complex Interfacial Structures with Tween 80 and Lecithin
• Molecular characterization and multifunctional evaluation of lactic acid bacteria isolated from traditional sourdough
• Molecular mechanism and therapeutic strategy of bile acids in Alzheimer's disease from the emerging perspective of the microbiota-gut-brain axis
• Multi-omics analysis reveals a feedback loop amplifying immune responses in acute graft-versus-host disease due to imbalanced gut microbiota and bile acid metabolism
• Multi-Omics Identified THDCA as a Key Contributor to Hyperlipidemia and as a Potential Therapeutic Agent
• Multi-omics insights into anti-colitis benefits of the synbiotic and postbiotic derived from wheat bran arabinoxylan and Limosilactobacillus reuteri
• Multi-omics reveal toxicity mechanisms underpinning nanoplastic in redclaw crayfish (Cherax quadricarinatus)
• Obeticholic acid ameliorates sepsis-induced renal mitochondrial damage by inhibiting the NF-kappab signaling pathway
• Personalized Microbial Fingerprint Associated with Differential Glycemic Effects of a Whole Grain Rye Intervention on Chinese Adults
• Polysaccharides from bile Arisaema exert an antipyretic effect on yeast-induced fever rats through regulating gut microbiota and metabolic profiling
• PPAR-Mediated Bile Acid Glucuronidation: Therapeutic Targets for the Treatment of Cholestatic Liver Diseases
• Protein Phosphatase 1 Regulatory Subunit 3 Beta rs4240624 Genotype Is Associated With Gallstones and With Significant Changes in Bile Lipidome
• Quantifying forms and functions of enterohepatic bile acid pools in mice
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• Reversal of hepatic accumulation of nordeoxycholic acid underlines the beneficial effects of cholestyramine on alcohol-associated liver disease in mice
• Role of gut microbiota and metabolomics in the lipid-lowering efficacy of statins among Chinese patients with coronary heart disease and hypercholesterolemia
• ROS-responsive and biomimetic nanoparticle delivery of obeticholic acid mitigates primary sclerosing cholangitis via mitochondria- induced apoptosis
• ROS-responsive nanoparticle delivery of obeticholic acid mitigate primary sclerosing cholangitis
• Screening of the Lipid-Lowering Probiotic Lactiplantibacillus Plantarum SDJ09 and its Anti-Obesity Mechanism
• Selection and characterization of spontaneous phage-resistant mutant of Limosilactobacillus fermentum
• Serum bile acids profiles are altered without change of the gut microbiota composition following a seven-day prednisolone therapy in severe alcoholic hepatitis
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• Si-Ni-San alleviates intestinal and liver damage in ulcerative colitis mice by regulating cholesterol metabolism
• Silymarin targets the FXR protein through microbial metabolite 7-keto-deoxycholic acid to treat MASLD in obese mice
• Spatial analysis of murine microbiota and bile acid metabolism during amoxicillin treatment
• Strain-dependent induction of primary bile acid 7-dehydroxylation by cholic acid
• The "crosstalk" between gut microbiota, metabolites and genes in diet-induced hepatic steatosis mice intervened with Cordyceps guangdongensis polysaccharides
• The fecal microbiota of patients with primary biliary cholangitis (PBC) causes PBC-like liver lesions in mice and exacerbates liver damage in a mouse model of PBC
• The metabolites mainly composed of lipids in tongue coating are non-invasive potential biomarkers for chronic gastritis
• Yellow tea polysaccharides protect against non-alcoholic fatty liver disease via regulation of gut microbiota and bile acid metabolism in mice