Disease: Amyotrophic lateral sclerosis type 2
- <em>C9orf72</em> gene networks in the human brain correlate with cortical thickness in C9-FTD and implicate vulnerable cell types
- 2(3H)-Dihydrofranolactone metabolites from Pleosporales sp. NUH322 as anti-amyotrophic lateral sclerosis drugs
- 2023 FDA TIDES (Peptides and Oligonucleotides) Harvest
- A model of human neural networks reveals NPTX2 pathology in ALS and FTLD
- AAV-NRIP gene therapy ameliorates motor neuron degeneration and muscle atrophy in ALS model mice
- Allele-Selective Thiomorpholino Antisense Oligonucleotides as a Therapeutic Approach for Fused-in-Sarcoma Amyotrophic Lateral Sclerosis
- ALS-linked SOD1 mutations impair mitochondrial-derived vesicle formation and accelerate aging
- Amyotrophic Lateral Sclerosis and Pain: A Narrative Review from Pain Assessment to Therapy
- An aberrant fused in sarcoma liquid droplet of amyotrophic lateral sclerosis pathological variant, R495X, accelerates liquid-solid phase transition
- Apilimod dimesylate in C9orf72 amyotrophic lateral sclerosis: a randomized phase 2a clinical trial
- Applications and limitations of electron 3D crystallography
- Artificial intelligence for screening and diagnosis of amyotrophic lateral sclerosis: a systematic review and meta-analysis
- Aspects of degradation and translation of the expanded C9orf72 hexanucleotide repeat RNA
- Assessment of Cerebral White Matter Involvement in Amyotrophic Lateral Sclerosis Patients With Disease Progression and Cognitive Impairment by Fixel-Based Analysis and Neurite Orientation Dispersion and Density Imaging
- Astrocytic Na<sup>+</sup>, K<sup>+</sup> ATPases in physiology and pathophysiology
- Automated Vowel Articulation Analysis in Connected Speech Among Progressive Neurological Diseases, Dysarthria Types, and Dysarthria Severities
- Case report: Asp194Ala variant in MFN2 is associated with ALS-FTD in an Italian family
- Causal relationship between imaging-derived phenotypes and neurodegenerative diseases: a Mendelian randomization study
- Cerebellar Micro-RNA Profile in a Mouse Model of Spinocerebellar Ataxia Type 2
- CHCHD2 P14L, found in amyotrophic lateral sclerosis, exhibits cytoplasmic mislocalization and alters Ca(2+) homeostasis
- Clinical prognostic factors predicting survival of motor neuron disease patients with gastrostomy: A retrospective analysis
- Cognitive performance of adult patients with SMA before and after treatment initiation with nusinersen
- Computational study of the motor neuron protein KIF5A to identify nsSNPs, bioactive compounds, and its key regulators
- Consequences of Disturbing Manganese Homeostasis
- CXCR2 Is Deregulated in ALS Spinal Cord and Its Activation Triggers Apoptosis in Motor Neuron-Like Cells Overexpressing hSOD1-G93A
- Cylindrical spirals and other concentric structures of skeletal muscle in patients with neurological diseases
- Design, <em>in silico</em> and pharmacological evaluation of a peptide inhibitor of BACE-1
- Development and Preclinical Evaluation of a Copper-64-Labeled Antibody Targeting Glycine-Alanine Dipeptides for PET Imaging of C9orf72-Associated Amyotrophic Lateral Sclerosis/Frontotemporal Dementia
- Distal hereditary motor neuropathies
- Disturbances in Muscle Energy Metabolism in Patients with Amyotrophic Lateral Sclerosis
- Divergent patterns of healthy aging across human brain regions at single-cell resolution reveal links to neurodegenerative disease
- Dominant stop-loss HNRNPA1 variants in juvenile-onset myopathy
- Dysregulated TDP-43 proteostasis perturbs excitability of spinal motor neurons during brainstem-mediated fictive locomotion in zebrafish
- Dysregulation of extracellular potassium distinguishes healthy ageing from neurodegeneration
- Dysregulation of persistent inward and outward currents in spinal motoneurons of symptomatic SOD1-G93A mice
- Early Alterations in Structural and Functional Properties in the Neuromuscular Junctions of Mutant FUS Mice
- Flexibility of brain dynamics is increased and predicts clinical impairment in relapsing-remitting but not in secondary progressive multiple sclerosis
- Genetic Downregulation of the Metabotropic Glutamate Receptor Type 5 Dampens the Reactive and Neurotoxic Phenotype of Adult ALS Astrocytes
- Hereditary spastic paraparesis type 18 (SPG18): new ERLIN2 variants in a series of Italian patients, shedding light upon genetic and phenotypic variability
- Heterogeneity of cortical pTDP-43 inclusion morphologies in amyotrophic lateral sclerosis
- Heteromeric amyloid filaments of ANXA11 and TDP-43 in FTLD-TDP Type C
- Histological Study on the Thickness of Gray Matter at the Summit and Bottom of Folium in Different Age Groups of Bangladeshi People
- Human CD4+CD25+ T cells expressing a chimeric antigen receptor against aberrant superoxide dismutase 1 trigger antigen-specific immunomodulation
- Identifying potential imaging markers for diffusion property changes in a mouse model of amyotrophic lateral sclerosis: Application of the continuous time random walk model to ultrahigh b-value diffusion-weighted MR images of spinal cord tissue
- Impacts of H(2) O(2) , SARM1 inhibition, and high NAm concentrations on Huntington's disease laser-induced degeneration
- Impacts of H<sub>2</sub> O<sub>2</sub> , SARM1 inhibition, and high NAm concentrations on Huntington's disease laser-induced degeneration
- Implications of ALS-Associated Mutations on Biochemical and Biophysical Features of hSOD1 and Aggregation Formation
- Insights on the Multifaceted Roles of Wild-Type and Mutated Superoxide Dismutase 1 in Amyotrophic Lateral Sclerosis Pathogenesis
- Involvement of Glucosamine 6 Phosphate Isomerase 2 (GNPDA2) Overproduction in beta-Amyloid- and Tau P301L-Driven Pathomechanisms
- Language impairment in sporadic and familial (type 8) amyotrophic lateral sclerosis: A comparative study
- Lipopolysaccharide triggers exacerbated microglial activation, excessive cytokine release and behavioural disturbances in mice with truncated Fused-in-Sarcoma Protein (FUS)
- Memory for emotional information in sporadic and Type 8 amyotrophic lateral sclerosis
- Mesenchymal stem cell therapy in amyotrophic lateral sclerosis (ALS) patients: A comprehensive review of disease information and future perspectives
- Misfolded alpha-synuclein in amyotrophic lateral sclerosis: Implications for diagnosis and treatment
- Modulating Golgi Stress Signaling Ameliorates Cell Morphological Phenotypes Induced by CHMP2B with Frontotemporal Dementia-Associated p.Asp148Tyr
- Negative features of sporadic amyotrophic lateral sclerosis: Motor neurons of Onuf's nucleus survive in ADAR2-conditional knockout mice
- Neurodegeneration Biomarkers in Adult Spinal Muscular Atrophy (SMA) Patients Treated with Nusinersen
- Neuroimmune characterization of optineurin insufficiency mouse model during ageing
- Nuclear pore pathology underlying multisystem proteinopathy type 3-related inclusion body myopathy
- omicSynth: An open multi-omic community resource for identifying druggable targets across neurodegenerative diseases
- Overlapping Neuroimmune Mechanisms and Therapeutic Targets in Neurodegenerative Disorders
- PAD2 dysregulation and aberrant protein citrullination feature prominently in reactive astrogliosis and myelin protein aggregation in sporadic ALS
- PERK modulation, with GSK2606414, Sephin1 or salubrinal, failed to produce therapeutic benefits in the SOD1G93A mouse model of ALS
- Plasma and salivary acetylcholinesterase activity in amyotrophic lateral sclerosis
- PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport
- Practical Three-Component Regioselective Synthesis of Drug-Like 3-Aryl(or heteroaryl)-5,6-dihydrobenzo[<em>h</em>]cinnolines as Potential Non-Covalent Multi-Targeting Inhibitors To Combat Neurodegenerative Diseases
- Preclinical translational platform of neuroinflammatory disease biology relevant to neurodegenerative disease
- Quantitative MRI Analysis of Brachial Plexus and Limb-Girdle Muscles in Upper Extremity Onset Amyotrophic Lateral Sclerosis
- Quantitative proteomics unveils known and previously unrecognized alterations in neuropathic nerves
- Radiologically inserted gastrostomy tube in neurological disease: A retrospective study
- Rare association between spinocerebellar ataxia and amyotrophic lateral sclerosis: a case series
- Repeat expansions in AR, ATXN1, ATXN2 and HTT in Norwegian patients diagnosed with amyotrophic lateral sclerosis
- Repurposing and clinical attributes of antidiabetic drugs for the treatment of neurodegenerative disorders
- Researches of calcium-activated chloride channel ANO1 intervening amyotrophic lateral sclerosis progression by activating EGFR and CaMKII signaling
- REVEALS-a longitudinal cohort study of multifaceted respiratory assessment in ALS
- Risdiplam improves subjective swallowing quality in non-ambulatory adult patients with 5q-spinal muscular atrophy despite advanced motor impairment
- Risk factors associated with amyotrophic lateral sclerosis based on the observational study: a systematic review and meta-analysis
- Role of senataxin in R-loop-mediated neurodegeneration
- Selective Vulnerability to Neurodegenerative Disease: Insights from Cell Type-Specific Translatome Studies
- Senataxin: A key actor in RNA metabolism, genome integrity and neurodegeneration
- SERCA1 Overexpression in Skeletal Muscle Attenuates Muscle Atrophy and Improves Motor Function in a Mouse Model of ALS
- Sex-Dependent Changes to the Intestinal and Hepatic Abundance of Drug Transporters and Metabolizing Enzymes in the SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis
- Sodium-glucose cotransporter 1/2 inhibition and risk of neurodegenerative disorders: A Mendelian randomization study
- Structured and disordered regions of Ataxin-2 contribute differently to the specificity and efficiency of mRNP granule formation
- Sunitinib for metastatic progressive phaeochromocytomas and paragangliomas: results from FIRSTMAPPP, an academic, multicentre, international, randomised, placebo-controlled, double-blind, phase 2 trial
- Surgical evolution in spinal dural arteriovenous fistula treatment-a 7 years monocentric experience
- T helper cell responses in adult diarrheal patients following natural infection with enterotoxigenic <em>Escherichia coli</em> are primarily of the Th17 type
- TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP
- The cholesterol depleting agent, (2-Hydroxypropyl)-ß-cyclodextrin, does not affect disease progression in SOD1<sup>G93A</sup> mice
- The polyglutamine protein ATXN2: from its molecular functions to its involvement in disease
- TUBA4A downregulation as observed in ALS <em>post-mortem</em> motor cortex causes ALS-related abnormalities in zebrafish
- TYK2 as a novel therapeutic target in Alzheimer's Disease with TDP-43 inclusions
- Vcp overexpression and leucine supplementation extend lifespan and ameliorate neuromuscular junction phenotypes of a SOD1G93A-ALS mouse model
- VCP/p97 UFMylation stabilizes BECN1 and facilitates the initiation of autophagy
- Ventilatory Effects of Acute Intermittent Hypoxia in Conscious Dystrophic Mice
- Weight and Muscle Mass Loss Associated with Acute Disease Can be Reversed with Appropriate Nutrition Therapy and Exercise in a Patient with Amyotrophic Lateral Sclerosisa: A Case Report
- Wild-type and pathogenic forms of ubiquilin 2 differentially modulate components of the autophagy-lysosome pathways