Disease: Alzheimer disease type 2
- <em>VWA3A</em>-derived ependyma promoter drives increased therapeutic protein secretion into the CSF
- 267 Spanish Exomes Reveal Population-Specific Differences in Disease-Related Genetic Variation
- 3-[[(3S)-1,2,3,4-Tetrahydroisoquinoline-3-carbonyl]amino]propanoic acid (THICAPA) is protective against Aβ42-induced toxicity in vitro and in an Alzheimer's Disease Drosophila
- A Novel Near-Infrared Fluorescence Probe THK-565 Enables In Vivo Detection of Amyloid Deposits in Alzheimer's Disease Mouse Model
- A Role for Blood-brain Barrier Dysfunction in Delirium following Non-Cardiac Surgery in Older Adults
- A Role for Cellular Prion Protein in Late-Onset Alzheimer's Disease: Evidence from Preclinical Studies
- A small molecule ApoE4-targeted therapeutic candidate that normalizes sirtuin 1 levels and improves cognition in an Alzheimer's disease mouse model
- A State-of-Art Review of the Vicious Circle of Sleep Disorders, Diabetes and Neurodegeneration Involving Metabolism and Microbiota Alterations
- Age-specific incidence rates for dementia and Alzheimer disease in NIA-LOAD/NCRAD and EFIGA families: National Institute on Aging Genetics Initiative for Late-Onset Alzheimer Disease/National Cell Repository for Alzheimer Disease (NIA-LOAD/NCRAD) and Estu
- Alzheimer's Disease-like Pathological Features in the Dorsal Hippocampus of Wild-Type Rats Subjected to Methionine-Diet-Evoked Mild Hyperhomocysteinaemia
- Amyloid Precursor Protein Changes Arrangement in a Membrane and Its Structure Depending on the Cholesterol Content
- APOE deficiency impacts neural differentiation and cholesterol biosynthesis in human iPSC-derived cerebral organoids
- APOEε4 potentiates amyloid β effects on longitudinal tau pathology
- Association between polymorphism rs2421943 of the insulin-degrading enzyme and schizophrenia: Preliminary report
- Association of CSF and PET markers of neurodegeneration with electroclinical progression in Lafora disease
- Association of HMGCR polymorphism with late-onset Alzheimer's disease in Han Chinese
- Association of TOMM40 polymorphisms with late-onset Alzheimer's disease in a Northern Han Chinese population
- Association of type 2 diabetes mellitus with dementia-related and non-dementia-related mortality among postmenopausal women: A secondary competing risks analysis of the women's health initiative
- Association of Type 2 Diabetes Mellitus With Perivascular Spaces and Cerebral Amyloid Angiopathy in Alzheimer's Disease: Insights From MRI Imaging
- Astaxanthin: A Marine Drug That Ameliorates Cerebrovascular-Damage-Associated Alzheimer's Disease in a Zebrafish Model via the Inhibition of Matrix Metalloprotease-13
- Astragaloside IV against Alzheimer's disease via microglia-mediated neuroinflammation using network pharmacology and experimental validation
- Astrocyte-targeting therapy rescues cognitive impairment caused by neuroinflammation via the Nrf2 pathway
- BAC Transgenic Expression of Human TREM2-R47H Remodels Amyloid Plaques but Unable to Reprogram Plaque-associated Microglial Reactivity in 5xFAD Mice
- BACE2 beyond β-processing of APP, its neuroprotective role in cerebrovascular endothelium
- BACE2 deficiency impairs expression and function of endothelial nitric oxide synthase in brain endothelial cells
- Benefits of use, and tolerance of, medium-chain triglyceride medical food in the management of Japanese patients with Alzheimer's disease: a prospective, open-label pilot study
- Case report: Mixed dementia associated with autoantibodies targeting the vesicular glutamate transporter 2
- Characterization of age- and stage-dependent impaired adult subventricular neurogenesis in 5XFAD mouse model of Alzheimer's disease
- Chewing and Swallowing Abilities of Persons Living With Dementia: A Systematic Review of Psychometric Properties of Instruments
- Classical cortical superficial siderosis presenting as extensive higher brain dysfunction with hypoperfusion in the frontoparietal lobe on the <sup>123</sup>I-IMP-SPECT: a case report
- Cognitive impairments predict the behavioral and psychological symptoms of dementia
- Critical evaluation of the reliability of DNA methylation probes on the Illumina MethylationEPIC BeadChip microarrays for dementia research
- Daytime Sleepiness Is Associated with Lower Cognitive Scores: The Look AHEAD Study
- Depressive Symptoms Longitudinally Mediate the Effect of Hyperglycemia on Memory Decline in Type 2 Diabetes
- Diabetes-Alzheimer's connection in older age: SGLT2 inhibitors as promising modulators of disease pathways
- Diet and lifestyle impact the development and progression of Alzheimer's dementia
- Diminished activation of excitatory neurons in the prelimbic cortex leads to impaired working memory capacity in mice
- Disease-associated astrocytes and microglia markers are upregulated in mice fed high fat diet
- Divergent patterns of healthy aging across human brain regions at single-cell resolution reveal links to neurodegenerative disease
- Effects of Probiotics on Colitis-Induced Exacerbation of Alzheimer's Disease in <em>App<sup>NL-G-F</sup></em> Mice
- Endothelial senescence alleviates cognitive impairment in a mouse model of Alzheimer's disease
- Exploring Rosiglitazone's Potential to Treat Alzheimer's Disease through the Modulation of Brain-Derived Neurotrophic Factor
- Exploring the molecular targets for Type 2 diabetes-induced Alzheimer's disease through bioinformatics analysis
- Exploring the Role of Hsp60 in Alzheimer's Disease and Type 2 Diabetes: Suggestion for Common Drug Targeting
- Focused ultrasound mitigates pathology and improves spatial memory in Alzheimer's mice and patients
- Genetic Factors Affecting Late-Onset Alzheimer's Disease Susceptibility
- Genome scan in familial late-onset Alzheimer's disease: a locus on chromosome 6 contributes to age-at-onset
- Healthy lifestyle and all-cause and cause-specific dementia in individuals with type 2 diabetes and the roles of diabetes duration and insulin use in UK Biobank cohort
- Heart failure-induced cognitive dysfunction is mediated by intracellular Ca<sup>2+</sup> leak through ryanodine receptor type 2
- Histological Study on the Thickness of Gray Matter at the Summit and Bottom of Folium in Different Age Groups of Bangladeshi People
- Identification of hybrid amyloid strains assembled from amyloid-β and human islet amyloid polypeptide
- Identifying potential patients with diabetes-related dementia: a descriptive approach using routinely collected data
- Impaired Retinal Capillary Function in Patients With Alzheimer Disease
- Incidence of Alzheimer's Disease in Men with Late-Life Hypertension Is Ameliorated by FOXO3 Longevity Genotype
- Increased risk of dementia among people with a history of fractures: a systematic review and meta-analysis of population-based studies
- Inhibitory effect of plain and functionalized graphene nanoplateles on hen egg white lysozyme fibrillation
- Intersectionality in Alzheimer's Disease: The Role of Female Sex and Black American Race in the Development and Prevalence of Alzheimer's Disease
- Intranasal Insulin Treatment Partially Corrects the Altered Gene Expression Profile in the Hippocampus of Developing Rats with Perinatal Iron Deficiency
- Investigation of Pancreatic-beta cells Role in the Biological Process of Ageing
- Knock-down of ROCK2 gene improves cognitive function and reduces neuronal apoptosis in AD mice by promoting mitochondrial fusion and inhibiting its division
- LAMP2A, LAMP2B and LAMP2C: similar structures, divergent roles
- Loss of normal Alzheimer's disease-associated Presenilin 2 function alters antiseizure medicine potency and tolerability in the 6-Hz focal seizure model
- Microbiota dysbiosis caused by dietetic patterns as a promoter of Alzheimer's disease through metabolic syndrome mechanisms
- Mining pure, strict epistatic interactions from high-dimensional datasets: ameliorating the curse of dimensionality
- Mitochondrial Effects of Hydromethylthionine, Rivastigmine and Memantine in Tau-Transgenic Mice
- Nanoscale reorganization of synaptic proteins in Alzheimer's disease
- Neuropathologic Changes of Alzheimer's Disease and Related Dementias: Relevance to Future Prevention
- Neuroprotective Effect of Thiazolidine-2,4-dione Derivatives on Memory Deficits and Neuropathological Symptoms of Dementia on a Scopolamine-Induced Alzheimer's Model in Adult Male Wistar Rats
- Neuroprotective effects of terpenoids against streptozotocin-nicotinamide-induced diabetic rats: An in silico, in vitro and in vivo study
- Nutritional redundancy in the human diet and its application in phenotype association studies
- Operational Modal Analysis of Near-Infrared Spectroscopy Measure of 2-Month Exercise Intervention Effects in Sedentary Older Adults with Diabetes and Cognitive Impairment
- Optimizing metabolic stability of phosphodiesterase 5 inhibitors: Discovery of a potent N-(pyridin-3-ylmethyl)quinoline derivative targeting synaptic plasticity
- Peripheral inflammation is a potential etiological factor in Alzheimer's disease
- Peripheral Mitochondrial Dysfunction: A Potential Contributor to the Development of Metabolic Disorders and Alzheimer's Disease
- Perivascular spaces mediate a relationship between diabetes and other cerebral small vessel disease markers in cerebrovascular and neurodegenerative diseases
- Potential Role of Glucagon-like Peptide-1 Receptor Agonists in the Treatment of Cognitive Decline and Dementia in Diabetes Mellitus
- Prebiotics modulate the microbiota-gut-brain axis and ameliorate cognitive impairment in APP/PS1 mice
- Presenilin-2 knock-In mice show severe depressive behavior via DVL3 downregulation
- Proline Isomerization: From the Chemistry and Biology to Therapeutic Opportunities
- Public acceptability of lumbar puncture in the diagnosis of Alzheimer's disease: a questionnaire-based single center study in China
- Reduced slow-wave activity and autonomic dysfunction during sleep precede cognitive deficits in Alzheimer's disease transgenic mice
- Relationship between the Presence of the <em>ApoE ε</em>4 Allele and EEG Complexity along the Alzheimer's Disease Continuum
- Repositioning of Anti-Diabetic Drugs against Dementia: Insight from Molecular Perspectives to Clinical Trials
- Reproducibility and Sensitivity of Resting-State fMRI in Patients With Parkinson's Disease Using Cross Validation-Based Data Censoring
- Research Progress on the Anti-Aging Potential of the Active Components of Ginseng
- Retinal microvascular complexity as a putative biomarker of biological age: a pilot study
- Should evidence of an autolysosomal de-acidification defect in Alzheimer and Parkinson diseases call for caution in prescribing chronic PPI and DMARD?
- State of the Science on Brain Insulin Resistance and Cognitive Decline Due to Alzheimer's Disease
- Stealth Liposomes Encapsulating a Potent ACAT1/SOAT1 Inhibitor F12511: Pharmacokinetic, Biodistribution, and Toxicity Studies in Wild-Type Mice and Efficacy Studies in Triple Transgenic Alzheimer's Disease Mice
- Targeted Metabolomic Analysis of the Eye Tissue of Triple Transgenic Alzheimer's Disease Mice at an Early Pathological Stage
- Targeting impaired nutrient sensing via the sirtuin pathway with novel compounds to prevent or treat dementia: A systematic review
- The cholesterol depleting agent, (2-Hydroxypropyl)-ß-cyclodextrin, does not affect disease progression in SOD1<sup>G93A</sup> mice
- The Expression of Epac2 and GluA3 in an Alzheimer's Disease Experimental Model and Postmortem Patient Samples
- The long-term effects of intermittent theta burst stimulation on Alzheimer's disease-type pathologies in APP/PS1 mice
- The role of signaling crosstalk of microglia in hippocampus on progression of ageing and Alzheimer's disease
- The therapeutic potential of carnosine: Focus on cellular and molecular mechanisms
- Triptolide improves Alzheimer's disease by regulating the NF‑κB signaling pathway through the lncRNA NEAT1/microRNA 361‑3p/TRAF2 axis
- TSPO Modulates Oligomeric Amyloid-β-Induced Monocyte Chemotaxis: Relevance for Neuroinflammation in Alzheimer's Disease
- TSPO PET brain inflammation imaging: A transdiagnostic systematic review and meta-analysis of 156 case-control studies
- Type 2 immunity in the brain and brain borders