• A further step toward possible treatment of alpha-1 antitrypsin deficiency associated liver disease
• A Further Step Toward Possible Treatment of Alpha-1 Antitrypsin Deficiency-Associated Liver Disease
• A novel in vitro cell model of the proteinase/antiproteinase balance observed in alpha-1 antitrypsin deficiency
• A novel pathological mutant reveals the role of torsional flexibility in the serpin breach in adoption of an aggregation-prone intermediate
• A Novel Provider Education Module to Enhance Detection of Alpha-1 Antitrypsin Deficiency
• A rare AAT variant presenting in a COPD patient: Q0 amersfoort mutation
• A Report on a Targeted Screening Population for Alpha-1-Antitrypsin Deficiency (AATD) in Central-Southern Italy
• A therapeutic challenge: managing severe atopic dermatitis with concurrent alpha-1-antitrypsin deficiency
• Alcohol consumption and liver phenotype of individuals with alpha-1 antitrypsin deficiency
• Allelic frequency of pathogenic alpha(1)-antitrypsin variants in the Japanese population: Results from a survey of open Japanese genetic variation databases
• Alpha 1-antitrypsin deficiency
• Alpha-1 Antitrypsin Deficiency
• Alpha-1 antitrypsin deficiency and pregnancy complications and birth outcomes: A population-based cohort study in Denmark
• Alpha-1 Antitrypsin Gene Variants in Patients without Severe Deficiency Diagnosed with Pulmonary Emphysema on Chest CT
• Alpha-1 Antitrypsin Phenotyping: An Unmet Educational Need of Healthcare Providers
• Alpha-1 Antitrypsin PI M Heterozygotes with Rare Variants: Do They Need a Clinical and Functional Follow-Up?
• Alpha-1 deficiency in severe asthma patients
• Alpha-1-Antitrypsin Deficiency in Children-Unmet Needs Concerning the Liver Manifestation
• Alpha-1-antitrypsin-deficiency is associated with lower cardiovascular risk: an approach based on federated learning
• Alpha(1)-Antitrypsin Deficiency
• An association between plasma levels of α2-macroglobulin and α1-antitrypsin in PiMM and PiZZ individuals differing in COPD presentation
• Anti-CELA1 antibody KF4 prevents emphysema by inhibiting stretch-mediated remodeling
• Antitrypsin deficiency: still more to learn about the lung after 60 years
• Assessing the efficacy of Alpha(1)-Proteinase inhibitor (human) augmentation therapy for Alpha(1)-Antitrypsin deficiency - Related emphysema: Challenges and opportunities
• Assessment and monitoring of lung disease in patients with severe alpha 1 antitrypsin deficiency: a european delphi consensus of the EARCO group
• Association of circulating Z-polymer with adverse clinical outcomes and liver fibrosis in adults with alpha-1 antitrypsin deficiency
• Augmentation Therapy Decreases Platelet-Neutrophil Aggregates in Alpha-1 Antitrypsin Deficiency
• Biodistribution and safety of a single rAAV3B-AAT vector for silencing and replacement of alpha-1 antitrypsin in Cynomolgus macaques
• Cardiovascular disease in Alpha 1 antitrypsin deficiency: an observational study assessing the role of neutrophil proteinase activity and the suitability of validated screening tools
• Case report of a novel alpha1-antitrypsin null variant in Türkiye: Q0_RİZE
• Characteristics associated with SF-36 in alpha-1 antitrypsin deficiency-associated COPD: a cross-sectional analysis
• Characteristics of alpha-1 antitrypsin deficiency related lung disease exacerbations using a daily symptom diary and urinary biomarkers
• Characteristics of Patients With Alpha-1 Antitrypsin Deficiency From Rural Appalachia: A Retrospective Single-Center Study
• Chest CT Imaging Provides More Information Than Chest Radiography Alone in Determining Extent of Physiologic Impairment in Pulmonary Sarcoidosis
• Clinical trial attitudes among individuals with Alpha-1 antitrypsin deficiency
• Computational Tools to Assist in Analyzing Effects of the SERPINA1 Gene Variation on Alpha-1 Antitrypsin (AAT)
• Cumulative occupational exposure to gases and fumes is associated with impairment in lung function and disease-related quality of life in a German COPD patient cohort
• Detection of Alpha-1 Antitrypsin Levels in Chronic Obstructive Pulmonary Disease in Respiratory Clinics in Spain: Results of the EPOCONSUL 2021 Audit
• Diagnosis of Alpha-1 Antitrypsin Deficiency (AATD) in Primary Care
• Differences in bile acid profiles between cholestatic diseases - Development of a high throughput assay for dried bloodspots
• Dipeptidyl peptidase 1 inhibition as a potential therapeutic approach in neutrophil-mediated inflammatory disease
• Efficacy and safety of the Spiration Valve System for the treatment of severe emphysema in patients with Alpha-1 antitrypsin deficiency (EMPROVE)
• Efficacy and safety of the spiration valve System for treatment of severe emphysema in patients with Alpha-1 antitrypsin deficiency (EMPROVE)
• Efficacy and safety of the spiration valve System™ for treatment of severe emphysema in patients with Alpha-1 antitrypsin deficiency (EMPROVE)
• European pathways of care in Alpha-1 Antitrypsin deficiency
• Fazirsiran for Adults With Alpha-1 Antitrypsin Deficiency Liver Disease: A Phase 2 Placebo Controlled Trial (SEQUOIA)
• Genetic background of pulmonary (vascular) diseases - how much is written in the codes?
• Genetic Epidemiology of Alpha-1 Antitrypsin Deficiency in Macaronesia
• Glycoengineered recombinant alpha1-antitrypsin results in comparable <em>in vitro</em> and <em>in vivo</em> activities to human plasma-derived protein
• Healthcare resource utilization and costs among patients with alpha-1 antitrypsin deficiency with liver and/or lung disease: a longitudinal retrospective study in the USA
• Identification of Alpha-1 Antitrypsin-Deficient Subjects with Normal Spirometry Who May Benefit from Alpha-1 Antitrypsin Replacement
• Improving the diagnosis of AATD with aid of serum protein electrophoresis: a prospective, multicentre, validation study
• Improving Wildfire Readiness Among Patients With Chronic Obstructive Pulmonary Disease and Asthma: Applying a Population Health Approach to Climate Change
• Increased risk of nonmelanoma skin cancer in patients with alpha-1 antitrypsin deficiency: A nationwide cohort study
• Induced Pluripotent Stem Cells and CRISPR-Cas9 Innovations for Treating Alpha-1 Antitrypsin Deficiency and Glycogen Storage Diseases
• KF4 anti-CELA1 Antibody and Purified alpha1-Antitrypsin Have Similar but Not Additive Efficacy in Preventing Emphysema in Murine alpha1-Antitrypsin Deficiency
• Liver disease associated with alpha1 antitrypsin deficiency
• Local Alpha1-Antitrypsin Accelerates the Healing of Tympanic Membrane Perforation in Mice
• Long-Term SGRQ Stability in a Cohort of Individuals with Alpha-1 Antitrypsin Deficiency-Associated Lung Disease
• Lung Single-Cell Transcriptomics in Alpha-1 Antitrypsin Deficiency
• Molecular confirmation of alpha 1-antitrypsin deficiency in liver transplant setting: A province-wide experience
• Monocyte NLRP3 inflammasome and interleukin-1beta activation modulated by alpha-1 antitrypsin therapy in deficient individuals
• Multiple Genes Core to ERAD, Macroautophagy and Lysosomal Degradation Pathways Participate in the Proteostasis Response in alpha1-Antitrypsin Deficiency
• Natural history of COPD: evolution of concepts
• Network-base approaches to identify therapeutic biomarkers in hepatocellular carcinoma and search for drug hunting utilizing molecular dynamics simulations
• Neutrophilic Panniculitides
• Panniculitis in alpha(1)-Antitrypsin Deficiency
• Patterns and unique features of infantile cholestasis among Arabs
• Personalised indication of augmentation therapy for emphysema associated with severe alpha-1 antitrypsin deficiency: a case series
• Plasma collagen neoepitopes are associated with multiorgan disease in the ACCESS and GRADS sarcoidosis cohorts
• Posttransplant Lymphoproliferative Disorder in a Patient With Alpha-1 Antitrypsin Deficiency: A Case Report
• Predicting Exacerbations in Alpha-1 Antitrypsin Deficiency Using Clinical and Pulmonary Function Tests: Portuguese EARCO Registry
• Predicting exacerbations in alpha1-antitrypsin deficiency using clinical and pulmonary function tests: Portuguese EARCO registry
• Prevalence of alpha-1 antitrypsin deficiency in patients with acute exacerbation of chronic obstructive pulmonary disease: Insights from a prospective study
• Prevalence of Cardiovascular Disease and Rate of Major Adverse Cardiovascular Events in Severe Alpha-1 Antitrypsin Deficiency COPD
• Primary biliary cholangitis with features of autoimmune hepatitis in a 19-year-old adolescent with 14q24.1q24.2 deletion: a case report
• Provider Education in Alpha 1 Antitrypsin Deficiency: Try Again, Fail Again, Fail Better
• Pulmonary Cellular Toxicity in Alpha-1 Antitrypsin Deficiency
• Pulmonary manifestations of alpha 1 antitrypsin deficiency
• Quantification of circulating alpha-1-antitrypsin polymers associated with different SERPINA1 genotypes
• Rare variants in alpha 1 antitrypsin deficiency: a systematic literature review
• Real-time PCR detection of PI*S and PI*Z alleles of SERPINA1 gene using SYBR green
• Recombinant Alpha-1 Antitrypsin-Fc Fusion Protein INBRX-101 in Adults With Alpha-1 Antitrypsin Deficiency: A Phase 1 Study
• Reconstitution of the <em>in vitro</em> STUB1-mediated ubiquitination reaction system for α-1 antitrypsin mutant Z protein
• Reconstitution of the in vitro STUB1-mediated ubiquitination reaction system for alpha-1 antitrypsin mutant Z protein
• Reduction of Z alpha-1 antitrypsin polymers in human iPSC-hepatocytes and mice by LRRK2 inhibitors
• Retrospective Database Analysis of Liver-Related Clinical Events in Adult and Pediatric Patients with Alpha-1 Antitrypsin Deficiency in the United States
• Review article: New developments in biomarkers and clinical drug development in alpha-1 antitrypsin deficiency-related liver disease
• Risk of lung disease in the PI*SS genotype of alpha-1 antitrypsin: an EARCO research project
• Sanofi buys Inhibrx and drug for alpha-1 antitrypsin deficiency for US$1.7 billion
• Sex-Differences in Alpha-1 Antitrypsin Deficiency: Data From the EARCO Registry
• Sirtuin3 promotes the degradation of hepatic Z alpha-1 antitrypsin through lipophagy
• Testing Alpha-1 Antitrypsin Deficiency in Black Populations
• The Expanding Scope of Alpha 1 Antitrypsin Deficiency
• The impact of alpha-1 antitrypsin deficiency alleles on lung cancer survival
• The value of alpha-1 antitrypsin functional testing and genotyping for the diagnosis of the MS variant of alpha-1 antitrypsin deficiency-associated panniculitis
• Tracing genetic diversity captures the molecular basis of misfolding disease
• Unusual case of bullous emphysema with superimposed pneumonia
• Validation of a method for measuring the antielastolytic activity of human circulating alpha1-antitrypsin
• Vanishing Lung Syndrome in a Young Male With Chronic Marijuana Use: A Case Report