Disease: Alpha-1 antitrypsin deficiency
- A novel pathological mutant reveals the role of torsional flexibility in the serpin breach in adoption of an aggregation-prone intermediate
- A Novel Provider Education Module to Enhance Detection of Alpha-1 Antitrypsin Deficiency
- A therapeutic challenge: managing severe atopic dermatitis with concurrent alpha-1-antitrypsin deficiency
- AATD as a genetic risk factor for aneurysmal disease
- AATD as a genetic risk factor for aneurysmal disease - Authors' reply
- Alpha-1 antitrypsin deficiency
- Alpha-1 Antitrypsin Deficiency
- Alpha-1 antitrypsin deficiency and pregnancy complications and birth outcomes: A population-based cohort study in Denmark
- Alpha-1 Antitrypsin Gene Variants in Patients without Severe Deficiency Diagnosed with Pulmonary Emphysema on Chest CT
- Alpha-1 Antitrypsin Phenotyping: An Unmet Educational Need of Healthcare Providers
- Alpha-1 Antitrypsin PI M Heterozygotes with Rare Variants: Do They Need a Clinical and Functional Follow-Up?
- Alpha-1 deficiency in severe asthma patients
- Alpha-1-Antitrypsin (A1AT) Proteotyping by LC-MS/MS
- Alpha-1-antitrypsin-deficiency is associated with lower cardiovascular risk: an approach based on federated learning
- Alpha-defensins inhibit ERK/STAT3 signaling during monocyte-macrophage differentiation and impede macrophage function
- An Alpha-1 Antitrypsin Deficiency Screening Study in Patients with Chronic Obstructive Pulmonary Disease, Bronchiectasis, or Asthma in Turkey
- An association between plasma levels of α2-macroglobulin and α1-antitrypsin in PiMM and PiZZ individuals differing in COPD presentation
- An Enzyme-Linked Immunosorbent Assay (ELISA) for Quantification of Circulating Pi*Z Alpha1-Antitrypsin Polymers
- Anti-CELA1 antibody KF4 prevents emphysema by inhibiting stretch-mediated remodeling
- Approaches to Therapeutic Gene Editing in Alpha-1 Antitrypsin Deficiency
- Are clinical trials into emerging drugs for the treatment of alpha-1 antitrypsin deficiency providing promising results?
- Baseline characteristics from a 3-year longitudinal study to phenotype subjects with COPD: the FOOTPRINTS study
- Biodistribution and safety of a single rAAV3B-AAT vector for silencing and replacement of alpha-1 antitrypsin in Cynomolgus macaques
- Cardiovascular disease in Alpha 1 antitrypsin deficiency: an observational study assessing the role of neutrophil proteinase activity and the suitability of validated screening tools
- Cardiovascular Risk Associated with Alpha-1 Antitrypsin Deficiency (AATD) Genotypes: A Meta-Analysis with Meta-Regressions
- Case report of a novel alpha1-antitrypsin null variant in Türkiye: Q0<sub>RİZE</sub>
- Case report: Self-administration of alpha-1 antitrypsin therapy: a report of two cases
- Characteristics associated with SF-36 in alpha-1 antitrypsin deficiency-associated COPD: a cross-sectional analysis
- Characteristics of alpha-1 antitrypsin deficiency related lung disease exacerbations using a daily symptom diary and urinary biomarkers
- Characteristics of Patients With Alpha-1 Antitrypsin Deficiency From Rural Appalachia: A Retrospective Single-Center Study
- Circulating Mitochondrial DNA Is Associated With High Levels of Fatigue in Two Independent Sarcoidosis Cohorts
- CLINICAL, LABORATORIAL AND EVOLUTIONARY ASPECTS OF PEDIATRIC PATIENTS WITH LIVER DISEASE DUE TO ALPHA 1-ANTITRYPSIN DEFICIENCY
- Computational Tools to Assist in Analyzing Effects of the SERPINA1 Gene Variation on Alpha-1 Antitrypsin (AAT)
- Correction to: Cigarette smoke exposed airway epithelial cells-derived EVs promote pro-inflammatory macrophage activation in alpha-1 antitrypsin deficiency
- Cumulative occupational exposure to gases and fumes is associated with impairment in lung function and disease-related quality of life in a German COPD patient cohort
- Danish children with ZZ-homozygous alpha-1 antitrypsin deficiency are more affected on liver parameters than children with heterozygosity
- Detection of Alpha-1 Antitrypsin Levels in Chronic Obstructive Pulmonary Disease in Respiratory Clinics in Spain: Results of the EPOCONSUL 2021 Audit
- Diagnosis of Alpha-1 Antitrypsin Deficiency (AATD) in Primary Care
- Dipeptidyl peptidase 1 inhibition as a potential therapeutic approach in neutrophil-mediated inflammatory disease
- Efficacy and safety of the Spiration Valve System for the treatment of severe emphysema in patients with Alpha-1 antitrypsin deficiency (EMPROVE)
- Efficacy and safety of the spiration valve System for treatment of severe emphysema in patients with Alpha-1 antitrypsin deficiency (EMPROVE)
- Efficacy and safety of the spiration valve System™ for treatment of severe emphysema in patients with Alpha-1 antitrypsin deficiency (EMPROVE)
- European pathways of care in Alpha-1 Antitrypsin deficiency
- Evaluation of body weight-based dosing, alternative dosing regimens, and treatment interruptions for alpha1-proteinase inhibitors and implications on biochemical efficacy in patients with alpha1-antitrypsin deficiency
- Evaluation of body weight-based dosing, alternative dosing regimens, and treatment interruptions for α1-proteinase inhibitors and implications on biochemical efficacy in patients with α1-antitrypsin deficiency
- Future Perspectives in the Diagnosis and Treatment of Liver Disease Associated with Alpha-1 Antitrypsin Deficiency
- Genetic epidemiology of alpha-1 antitrypsin deficiency in Macaronesia
- Glioblastoma Multiforme in a Patient With Alpha-1-Antitrypsin Deficiency
- Glycoengineered recombinant alpha1-antitrypsin results in comparable <em>in vitro</em> and <em>in vivo</em> activities to human plasma-derived protein
- Healthcare resource utilization and costs among patients with alpha-1 antitrypsin deficiency with liver and/or lung disease: a longitudinal retrospective study in the USA
- Identification of Alpha-1 Antitrypsin-Deficient Subjects with Normal Spirometry Who May Benefit from Alpha-1 Antitrypsin Replacement
- Impact of the COVID-19 pandemic on well-being and quality of life of patients with alpha-1-antitrypsin deficiency
- Improving the diagnosis of AATD with aid of serum protein electrophoresis: a prospective, multicentre, validation study
- Increased risk of nonmelanoma skin cancer in patients with alpha-1 antitrypsin deficiency: A nationwide cohort study
- Initial alpha-1 antitrypsin screening in Turkish patients with chronic obstructive pulmonary disease
- Intrahepatic cholestasis of pregnancy and theory of inheritance of the disease. Literature review
- Lipoproteins in Negative Feedback with Alpha-1 Antitrypsin
- Liver disease associated with alpha1 antitrypsin deficiency
- Liver disease epidemiology and burden in patients with alterations in plasma protein metabolism: German retrospective insurance claims analysis
- Long-Term SGRQ Stability in a Cohort of Individuals with Alpha-1 Antitrypsin Deficiency-Associated Lung Disease
- Measuring of Alpha-1 Antitrypsin Concentration by Nephelometry or Turbidimetry
- Molecular confirmation of alpha 1-antitrypsin deficiency in liver transplant setting: A province-wide experience
- Monocyte NLRP3 inflammasome and interleukin-1beta activation modulated by alpha-1 antitrypsin therapy in deficient individuals
- Natural history of COPD: evolution of concepts
- Neonatal cholestasis in children with Alpha-1-AT deficiency is a risk for earlier severe liver disease with male predominance
- Network-base approaches to identify therapeutic biomarkers in hepatocellular carcinoma and search for drug hunting utilizing molecular dynamics simulations
- Neutrophilic Panniculitides
- Nine controversial questions about augmentation therapy for alpha-1 antitrypsin deficiency: a viewpoint
- Plasma levels of alpha(1)-antitrypsin-derived C-terminal peptides in PiMM and PiZZ COPD patients
- Plasma levels of α<sub>1</sub>-antitrypsin-derived C-terminal peptides in PiMM and PiZZ COPD patients
- Predicting exacerbations in alpha1-antitrypsin deficiency using clinical and pulmonary function tests: Portuguese EARCO registry
- Prevalence of Cardiovascular Disease and Rate of Major Adverse Cardiovascular Events in Severe Alpha-1 Antitrypsin Deficiency COPD
- Primary biliary cholangitis with features of autoimmune hepatitis in a 19-year-old adolescent with 14q24.1q24.2 deletion: a case report
- Probing of the reactive center loop region of alpha-1-antitrypsin by mutagenesis predicts new type-2 dysfunctional variants
- Provider Education in Alpha 1 Antitrypsin Deficiency: Try Again, Fail Again, Fail Better
- Pulmonary Cellular Toxicity in Alpha-1 Antitrypsin Deficiency
- Pulmonary manifestations of alpha 1 antitrypsin deficiency
- Pulmonary Rehabilitation for Chronic Obstructive Pulmonary Disease Patients with Underlying Alpha-1 Antitrypsin Deficiency: A Systematic Review and Practical Recommendations
- Quantification of circulating alpha-1-antitrypsin polymers associated with different SERPINA1 genotypes
- Rare variants in alpha 1 antitrypsin deficiency: a systematic literature review
- Reconstitution of the <em>in vitro</em> STUB1-mediated ubiquitination reaction system for α-1 antitrypsin mutant Z protein
- Reconstitution of the in vitro STUB1-mediated ubiquitination reaction system for alpha-1 antitrypsin mutant Z protein
- Response to the letter to the editor "Alpha-1 antitrypsin deficiency: impact of its relevance in hematology"
- Results of the Implementation of a Case-Finding Program for Alpha-1 Antitrypsin Deficiency in COPD Patients
- Review article: New developments in biomarkers and clinical drug development in alpha-1 antitrypsin deficiency-related liver disease
- Risk factors of prolonged diarrhea in children under 2 years old
- Sanger and Next-Generation Sequencing of AAT
- Sanofi buys Inhibrx and drug for alpha-1 antitrypsin deficiency for US$1.7 billion
- Sarcopenia is associated with osteopenia and impaired quality of life in children with genetic intrahepatic cholestatic liver disease
- Single vs Bilateral Lung Transplant in the Management of Patients With Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis
- Sirtuin3 promotes the degradation of hepatic Z alpha-1 antitrypsin through lipophagy
- Testing Alpha-1 Antitrypsin Deficiency in Black Populations
- The Expanding Scope of Alpha 1 Antitrypsin Deficiency
- The impact of alpha-1 antitrypsin deficiency alleles on lung cancer survival
- Tracing genetic diversity captures the molecular basis of misfolding disease
- Transplant with MZ genotype liver: what is the clinical pulmonary picture after 30 years? a case report and review of the literature
- Type 1 diabetes contributes to combined pulmonary fibrosis and emphysema in male alpha 1 antitrypsin deficient mice
- Undiagnosed Alpha-1 Antitrypsin Deficiency and the Perpetuation of Lung Health Inequity
- Unusual case of bullous emphysema with superimposed pneumonia
- Vanishing Lung Syndrome in a Young Male With Chronic Marijuana Use: A Case Report