• 2-Bromo-1,4-Naphthalenedione promotes CD8(+) T cell expansion and limits Th1/Th17 to mitigate experimental autoimmune encephalomyelitis
• 25 Hydroxyvitamin D and Cytokine Profile in Patients With Relapsing-Remitting Multiple Sclerosis
• A Camelid-Derived STAT-Specific Nanobody Inhibits Neuroinflammation and Ameliorates Experimental Autoimmune Encephalomyelitis (EAE)
• A new class of 7-deazaguanine agents targeting autoimmune diseases: dramatic reduction of synovial fibroblast IL-6 production from human rheumatoid arthritis patients and improved performance against murine experimental autoimmune encephalomyelitis
• A novel PROTAC molecule dBET1 alleviates pathogenesis of experimental autoimmune encephalomyelitis in mice by degrading BRD4
• ACKR3 Antagonism Enhances the Repair of Demyelinated Lesions Through Both Immunomodulatory and Remyelinating Effects
• Administration of ROS-Scavenging Cerium Oxide Nanoparticles Simply Mixed with Autoantigenic Peptides Induce Antigen-Specific Immune Tolerance against Autoimmune Encephalomyelitis
• Amelioration of experimental autoimmune encephalomyelitis by gemfibrozil in mice via PPARbeta/delta: implications for multiple sclerosis
• Amniotic fluid stem cell-derived extracellular vesicles educate type 2 conventional dendritic cells to rescue autoimmune disorders in a multiple sclerosis mouse model
• An IL-23-STAT4 pathway is required for the proinflammatory function of classical dendritic cells during CNS inflammation
• Animal model of multiple sclerosis: Experimental autoimmune encephalomyelitis
• Apelin modulates inflammation and leukocyte recruitment in experimental autoimmune encephalomyelitis
• Asymptomatic herpes simplex virus brain infection elicits cellular senescence phenotypes in the central nervous system of mice suffering multiple sclerosis-like disease
• atRA Attenuates High Salt-Driven EAE Mainly Through Suppressing Th17-Like Regulatory T Cell Response Mediated by the Inhibition of IL-23R Signaling Pathway
• Autoimmune inflammation triggers aberrant astrocytic calcium signaling to impair synaptic plasticity
• Cavbeta3 Contributes to the Maintenance of the Blood-Brain Barrier and Alleviates Symptoms of Experimental Autoimmune Encephalitis
• Cellular Therapy in Experimental Autoimmune Encephalomyelitis as an Adjuvant Treatment to Translate for Multiple Sclerosis
• Characterization of spinal cord tissue-derived extracellular vesicles in neuroinflammation
• Circulating platelets modulate oligodendrocyte progenitor cell differentiation during remyelination
• Correction to Immune Checkpoint Ligand Bioengineered Schwann Cells as Antigen-Specific Therapy for Experimental Autoimmune Encephalomyelitis
• Correlation of Visual System Biomarkers With Motor Deficits in Experimental Autoimmune Encephalomyelitis-Optic Neuritis
• Current Knowledge about Nonclassical Monocytes in Patients with Multiple Sclerosis, a Systematic Review
• Current understanding of cardiovascular autonomic dysfunction in multiple sclerosis
• Defective Integrator activity shapes the transcriptome of patients with multiple sclerosis
• Deferoxamine preconditioning of canine stem cell derived extracellular vesicles alleviates inflammation in an EAE mouse model through STAT3 regulation
• Deficiency of galactosylceramidase in adult oligodendrocytes worsens the neurological deficits and shortens the survival during chronic experimental allergic encephalomyelitis
• Dietary ellagic acid therapy for CNS autoimmunity: Targeting on Alloprevotella rava and propionate metabolism
• Differences in the characteristics and functions of brain and spinal cord regulatory T cells
• Dosage and organic acid residue of MOG(35-55) peptide influences immunopathology and development of BCG induced experimental autoimmune encephalomyelitis (EAE)
• Electrical stimulation of the vagus nerve ameliorates inflammation and disease activity in a rat EAE model of multiple sclerosis
• Experimental Autoimmune Encephalomyelitis Influences GH-Axis in Female Rats
• Exploring the role of mesenchymal stem cells in modulating immune responses via Treg and Th2 cell activation: insights from mouse model of multiple sclerosis
• Expression of components involved in cholesterol homeostasis maintenance during experimental autoimmune encephalomyelitis in rat spinal cord
• Extracellular vesicles containing miR-181a-5p as a novel therapy for experimental autoimmune encephalomyelitis-induced demyelination
• Fluorinated apelin-13 mediated neuroprotective effect in multiple sclerosis models
• Fluorinated apelin-13 mediates neuroprotective effects in multiple sclerosis models
• Follicular CD8⁺ T cells promote immunoglobulin production and demyelination in multiple sclerosis and a murine model
• Formyl peptide receptor 2 regulates dendritic cell metabolism and Th17 cell differentiation during neuroinflammation
• Functional Role of DDR1 in Oligodendrocyte Signaling Mechanism in Association with Myelination and Remyelination Process in the Central Nerve System
• Gut microbial factors predict disease severity in a mouse model of multiple sclerosis
• GV-971 attenuates the progression of neuromyelitis optica in murine models and reverses alterations in gut microbiota and associated peripheral abnormalities
• Hederagenol improves multiple sclerosis by modulating Th17 cell differentiation
• Histopathological evaluation of the lungs in experimental autoimmune encephalomyelitis
• How does Nogo-A signalling influence mitochondrial function during multiple sclerosis pathogenesis?
• HPGD: An Intermediate Player in Microglial Polarization and Multiple Sclerosis Regulated by Nr4a1
• Identifying Diagnostic Markers and Constructing Predictive Models for Oxidative Stress in Multiple Sclerosis
• IL-6 Inhibition as a Therapeutic Target in Aged Experimental Autoimmune Encephalomyelitis
• Immune Checkpoint Inhibition-related Neuroinflammation Disrupts Cognitive Function
• Impaired olfactory performance and anxiety-like behavior in a rat model of multiple sclerosis are associated with enhanced adenosine signaling in the olfactory bulb via A₁R, A_2BR, and A₃
• Inhibition of BCAT1-mediated cytosolic leucine metabolism regulates Th17 responses via the mTORC1-HIF1α pathway
• Integrated elemental analysis supports targeting copper perturbations as a therapeutic strategy in multiple sclerosis
• Interleukin-10 contrasts inflammatory synaptopathy and central neurodegenerative damage in multiple sclerosis
• Intraperitoneal injection of mesenchymal stem cells-conditioned media (MSCS-CM) treated monocyte can potentially alleviate motor defects in experimental autoimmune encephalomyelitis female mice; An original experimental study
• Isoliquiritigenin alleviates experimental autoimmune encephalomyelitis by modulating inflammatory and neuroprotective reactive astrocytes
• JAK2/STAT3 Pathway Inhibition by AG490 Ameliorates Experimental Autoimmune Encephalomyelitis via Regulation of Th17 Cells and Autophagy
• Loss of Cells in the Retinal Ganglion Cell Layer as an Early Indication of Neurodegeneration in Multiple Sclerosis
• Melatonin synergistically potentiates the effect of methylprednisolone on reducing neuroinflammation in the experimental autoimmune encephalomyelitis mouse model of multiple sclerosis
• Methylprednisolone Modulates the Tfr/Tfh ratio in EAE-Induced Neuroinflammation through the PI3K/AKT/FoxO1 and PI3K/AKT/mTOR Signalling Pathways
• Microglia and Dendritic Cells as a Source of IL-6 in a Mouse Model of Multiple Sclerosis
• Mild Disease Course of Experimental Autoimmune Encephalomyelitis without Pertussis Toxin: Brain Transcriptome Analysis Reveals Similar Signaling to Active Lesions in Multiple Sclerosis
• MOG CNS Autoimmunity and MOGAD
• Myelin oligodendrocyte glycoprotein reactive Th17 cells drive Janus Kinase 1 dependent transcriptional reprogramming in astrocytes and alter cell surface cytokine receptor profiles during experimental autoimmune encephalomyelitis
• Myelin-reactive B cells exacerbate CD4⁺ T cell-driven CNS autoimmunity in an IL-23-dependent manner
• Niacin produces an inconsistent treatment response in the EAE model of multiple sclerosis
• Novel model of multiple sclerosis induced by EBV-like virus generates a unique B cell population
• Obesity intensifies sex-specific interferon signaling to selectively worsen central nervous system autoimmunity in females
• Oligodendrocyte precursor cell-derived exosomes combined with cell therapy promote clinical recovery by immunomodulation and gliosis attenuation
• Oxidative Stress Markers in Multiple Sclerosis
• Oxytocin and Vasopressin Gene Expression in the Brain as Potential Biomarkers for Cannabidiol Therapeutic Efficacy
• PD-1 regulation of pathogenic IL-17-secreting gammadelta T cells in experimental autoimmune encephalomyelitis
• Perivascular B cells link intestinal angiogenesis to immunity and to the gut-brain axis during neuroinflammation
• Peroxynitrite reduces Treg cell expansion and function by mediating IL-2R nitration and aggravates multiple sclerosis pathogenesis: One sentence summary: Peroxynitrite-mediated Treg IL-2R nitration impacts on multiple sclerosis
• Phagolysosomal resistance hypothesized to be a danger signal
• Pin1 maintains the effector program of pathogenic Th17 cells in autoimmune neuroinflammation
• Probing the basis of disease heterogeneity in multiple sclerosis using genetically diverse mice
• Protocol for delivering proteins, peptides, and shRNAs via the intrathecal route in the experimental allergic encephalomyelitis mouse model
• Quercetin regulates dendritic cell activation by targeting STAT4 in the treatment of experimental autoimmune encephalomyelitis
• Re-emergence of T lymphocyte-mediated synaptopathy in progressive multiple sclerosis
• Re-establishing immune tolerance in multiple sclerosis: focusing on novel mechanisms of mesenchymal stem cell regulation of Th17/Treg balance
• Retraction notice to "Matrine regulates glutamate-related excitotoxic factors in experimental autoimmune encephalomyelitis" [Neurosci. Lett. 560 (2014) 92-97]
• RNF213 promotes Treg cell differentiation by facilitating K63-linked ubiquitination and nuclear translocation of FOXO1
• Short-chain fatty acids suppresses astrocyte activation by amplifying Trp-AhR-AQP4 signaling in experimental autoimmune encephalomyelitis mice
• Single-cell profiling indicates a high similarity between immune cells in the cerebrospinal fluid and in meningeal ectopic lymphoid tissue in experimental autoimmune encephalomyelitis
• Single-Cell RNA Sequencing Reveals Transcriptional Landscape of Neutrophils and Highlights the Role of TREM-1 in EAE
• Siponimod treatment response shows partial BDNF dependency in multiple sclerosis models
• Spontaneous human CD8 T cell and autoimmune encephalomyelitis-induced CD4/CD8 T cell lesions in the brain and spinal cord of HLA-DRB1*15-positive multiple sclerosis humanized immune system mice
• Suppressive effect of the anesthetic propofol on the T cell function and T cell-dependent immune responses
• SWI/SNF chromatin remodeling factor BAF60b restrains inflammatory diseases by affecting regulatory T cell migration
• Synergistic Targeting of Innate Receptors TLR7 and NOD2 for Therapeutic Intervention in Multiple Sclerosis
• Targeting CNS myeloid infiltrates provides neuroprotection in a progressive multiple Sclerosis model
• Targeting the muscarinic M1 receptor with a selective, brain-penetrant antagonist to promote remyelination in multiple sclerosis
• The Antidepressant- and Anxiolytic-Like Effects of the Phosphodiesterase Type-5 Inhibitor Tadalafil are Associated with the Modulation of the Gut-Brain Axis During CNS Autoimmunity
• The chemically stable analogue of resolvin D1 ameliorates experimental autoimmune encephalomyelitis by mediating the resolution of inflammation
• The hidden link: How oral and respiratory microbiomes affect multiple sclerosis
• The Mechanisms of Mesenchymal Stem Cells in the Treatment of Experimental Autoimmune Encephalomyelitis
• Therapeutic effects and mechanisms of fecal microbiota transplantation on EAE partly through HPA axis-mediated neuroendocrine regulation
• Therapeutic role of interferon-gamma in experimental autoimmune encephalomyelitis is mediated through a tolerogenic subset of splenic CD11b(+) myeloid cells
• TPPB modulates PKC activity to attenuate neuroinflammation and ameliorate experimental multiple sclerosis
• Transcriptional network analysis of peripheral blood leukocyte subsets in multiple sclerosis identifies a pathogenic role for a cytotoxicity-associated gene network in myeloid cells
• Transplantation of human umbilical cord mesenchymal stem cells optimized with IFN-γ is a potential procedure for modification of motor impairment in multiple sclerosis cases: a preclinical systematic review and meta-analysis study