Disease: African trypanosomiasis
- <em>Crosspteryx fibrifuga</em> leaf extract enhances host resistance to <em>Trypanosoma congolense</em> infection in mice by regulating host immune response and disrupting the activity of parasite superoxide dismutase enzyme
- <em>In Vitro</em> and <em>In Vivo</em> Trypanocidal Efficacy of Nitrofuryl- and Nitrothienylazines
- 100 years since the publication of the suramin formula
- A Bayesian maximum entropy model for predicting tsetse ecological distributions
- A man in his sixties with life-threatening febrile illness after travel abroad
- A scoping review on tsetse fly blood meal sources and its assay methods since 1956 to 2022
- Adaptation of CUT&RUN for use in African trypanosomes
- Adaptation of CUT&RUN for use in African trypanosomes
- African Trypanosomiasis
- An <em>In vitro</em> and <em>in silico</em> investigation of the antitrypanosomal activities of the stem bark extracts of <em>Anopyxis klaineana</em> (Pierre) Engl
- An essential <em>Trypanosoma brucei</em> protein kinase: a functional analysis of regulation and the identification of inhibitors
- Animal trypanosomosis eliminated in a major livestock production region in Senegal following the eradication of a tsetse population
- Anti-parasitic benzoxaboroles are ineffective against Theileria parva in vitro
- Antigiardial and antiamebic activities of fexinidazole and its metabolites: new drug leads for giardiasis and amebiasis
- Antiprotozoal Activity of Plants Used in the Management of Sleeping Sickness in Angola and Bioactivity-Guided Fractionation of <em>Brasenia schreberi</em> J.F.Gmel and <em>Nymphaea lotus</em> L. Active against <em>T. b. rhode
- Antitrypanosomal Chloronitrobenzamides
- Ascofuranone antibiotic is a promising trypanocidal drug for nagana
- Characterization of the Bacterial Profile from Natural and Laboratory <em>Glossina</em> Populations
- Coinfection with <em>Schistosoma mansoni</em> Enhances Disease Severity in Human African Trypanosomiasis
- Coinfection with Schistosoma mansoni Enhances Disease Severity in Human African Trypanosomiasis
- Comparison of stochastic and deterministic models for gambiense sleeping sickness at different spatial scales: A health area analysis in the DRC
- Conducting active screening for human African trypanosomiasis with rapid diagnostic tests: The Guinean experience (2016-2021)
- Consistent detection of Trypanosoma brucei but not T. congolense DNA in faeces of experimentally infected cattle
- Cytotoxicity and immunological impact of Trypanosoma sp. infection on blood parameters of wild African catfish, Clarias gariepinus
- Depolymerization of SUMO chains induces slender to stumpy differentiation in T. brucei bloodstream parasites
- Design, Synthesis, and Evaluation of An Anti-trypanosomal [1,2,4]Triazolo[1,5-a]pyrimidine Probe for Photoaffinity Labeling Studies
- Development of Novel Peptidyl Nitriles Targeting Rhodesain and Falcipain-2 for the Treatment of Sleeping Sickness and Malaria
- Differences in gene expression profiles in early and late stage rhodesiense HAT individuals in Malawi
- Discovery of an orally active nitrothiophene-based antitrypanosomal agent
- Discovery of Strong 3-Nitro-2-Phenyl-<em>2H</em>-Chromene Analogues as Antitrypanosomal Agents and Inhibitors of <em>Trypanosoma cruzi</em> Glucokinase
- Distinct structural motifs are necessary for targeting and import of Tim17 in <em>Trypanosoma brucei</em> mitochondrion
- Diversity of Glossinidae (Diptera) species in The Gambia in relation to vegetation
- Elimination of human African trypanosomiasis: The long last mile
- Epidemiological study on cattle trypanosomiasis and its vectors distributions in the Gambella regional state, southwestern Ethiopia
- Evaluating for correlations between metabolites in patients receiving immunotherapy for metastatic or recurrent NSCLC: an exploratory study based on two cohorts
- Experimental genetic crosses in tsetse flies of the livestock pathogen Trypanosoma congolense savannah
- Exploring microalgal and cyanobacterial metabolites with antiprotozoal activity against Leishmania and Trypanosoma parasites
- Exploring the Potential of Natural Products as Antiparasitic Agents for Neglected Tropical Diseases
- Fexinidazole induced cytotoxicity is distinct from related anti-trypanosome nitroaromatic drugs
- First comprehensive untargeted metabolomics study of suramin-treated Trypanosoma brucei: an integrated data analysis workflow from multifactor data modelling to functional analysis
- FLAgellum Member 8 modulates extravascular distribution of African trypanosomes
- Genetic Diversity of Trypanosomes Infesting Cattle from Savannah District in North of Côte d'Ivoire Using Conserved Genomic Signatures: rRNA, ITS1 and gGAPDH
- Ginkgo biloba attenuated detrimental inflammatory and oxidative events due to Trypanosoma brucei rhodesiense in mice treated with melarsoprol
- How plastic are upper thermal limits? A comparative study in tsetse (family: Glossinidae) and wider Diptera
- Human African Trypanosomiasis
- Identification of transport systems involved in eflornithine delivery across the blood-brain barrier
- Impact of a small-scale tsetse fly control operation with deltamethrin impregnated "Tiny Targets" on tsetse density and trypanosomes' circulation in the Campo sleeping sickness focus of South Cameroon
- In Silico and In Vitro Search for Dual Inhibitors of the <em>Trypanosoma brucei</em> and <em>Leishmania major</em> Pteridine Reductase 1 and Dihydrofolate Reductase
- In vitro and in vivo antitrypanosomal activity of the fresh leaves of Ranunculus Multifidus Forsk and its major compound anemonin against Trypanosoma congolense field isolate
- In vitro antitrypanosomal activity of synthesized nitrofurantoin-triazole hybrids against Trypanosoma species causing animal African trypanosomosis
- In vitro trypanocidal potency and in vivo treatment efficacy of oligomeric ethylene glycol-tethered nitrofurantoin derivatives
- Insights to Design New Drugs against Human African Trypanosomiasis Targeting Rhodesain using Covalent Docking, Molecular Dynamics Simulations, and MM-PBSA Calculations
- Kagimminols A and B, Cembrene-Type Diterpenes from an <em>Okeania</em> sp. Marine Cyanobacterium
- Key Contributions by the Swiss Tropical and Public Health Institute Towards New and Better Drugs for Tropical Diseases
- Lead Optimization of the 5-Phenylpyrazolopyrimidinone NPD-2975 toward Compounds with Improved Antitrypanosomal Efficacy
- Limited impact of vector control on the population genetic structure of Glossina fuscipes fuscipes from the sleeping sickness focus of Maro, Chad
- Livestock, pathogens, vectors, and their environment: A causal inference-based approach to estimating the pathway-specific effect of livestock on human African trypanosomiasis risk
- Mitigation of Trypanosoma congolense-Associated Anemia and Expression of Trans-sialidase (TconTS) Gene Variants by Eugenol
- Modelled impact of Tiny Targets on the distribution and abundance of riverine tsetse
- Novel aroyl guanidine anti-trypanosomal compounds that exert opposing effects on parasite energy metabolism
- Performance of diagnostic tests for Trypanosoma brucei brucei in experimentally infected pigs
- Polyamine Metabolism for Drug Intervention in Trypanosomatids
- Polyaromatic <em>Bis</em>(indolyl)methane Derivatives with Antiproliferative and Antiparasitic Activity
- Prevalence of African animal trypanosomiasis among livestock and domestic animals in Uganda: a systematic review and meta-regression analysis from 1980 to 2022
- Prevalence of Spiroplasma and interaction with wild Glossina tachinoides microbiota
- Privileged small molecules against neglected tropical diseases: A perspective from structure activity relationships
- Prophylactic activity of orally administered dry-heat-sterilized Acremonium egyptiacum against Trypanosoma congolense-induced animal African trypanosomosis
- Q586B2 is a crucial virulence factor during the early stages of Trypanosoma brucei infection that is conserved amongst trypanosomatids
- Reemergence of Human African Trypanosomiasis Caused by Trypanosoma brucei rhodesiense, Ethiopia
- Repurposing Know-how for Drug Development: Case Studies from the Swiss Tropical and Public Health Institute
- Seasonal variation in tsetse fly apparent density and Trypanosoma spp. infection rate and occurrence of drug-resistant trypanosomes in Lambwe, Kenya
- Second stage human African Trypanosomiasis with Trypanosoma brucei rhodesiense treated with fexinidazole
- Selenosugars targeting the infective stage of Trypanosoma brucei with high selectivity
- Spatial confinement of Trypanosoma brucei in microfluidic traps provides a new tool to study free swimming parasites
- Study on the underlying molecular mechanism of benzene-induced nervous system damage in mice based on tandem mass tag (TMT) proteomics
- Suramin, an antiparasitic drug, stimulates adipocyte differentiation and promotes adipogenesis
- Synthesis and characterization of I-BET151 derivatives for use in identifying protein targets in the African trypanosome
- Synthetic arrest of Man<sub>5</sub>GlcNAc<sub>2</sub>-PP-Dol increases procyclin mRNA level and induces cell death in the bloodstream form Trypanosoma brucei brucei
- The current status of neglected tropical diseases in Japan: A scoping review
- The elimination of human African trypanosomiasis: Monitoring progress towards the 2021-2030 WHO road map targets
- The Evolving Spectrum of Human African Trypanosomiasis
- The Hidden Hand of Asymptomatic Infection Hinders Control of Neglected Tropical Diseases: A Modeling Analysis
- The internal transcribed spacer 1 sequence polymorphism brings updates to tsetse species distribution in the northern Cameroon: Importance in planning efficient vector control
- The lymphatic system favours survival of a unique T. brucei population
- The murine meninges acquire lymphoid tissue properties and harbour autoreactive B cells during chronic Trypanosoma brucei infection
- The pathogenicity of blood stream and central nervous system forms of <em>Trypanosoma brucei rhodesiense</em> trypanosomes in laboratory mice: a comparative study
- The pipeline for drugs for control and elimination of neglected tropical diseases: 2. Oral anti-infective drugs and drug combinations for off-label use
- The role of tryptophan derivatives as anti-kinetoplastid agents
- Therapeutic efficacy of β-sitosterol treatment on <em>Trypanosoma congolense</em> infection, anemia development, and trans-sialidase (<em>TconTS1</em>) gene expression
- Therapeutic Strategies against <em>Leishmania</em> and <em>Trypanosoma</em>
- To Explore Potential Inhibitors Against Various Enzymatic Targets of Human African Trypanosomiasis
- Tractable Quinolone Hydrazides Exhibiting Sub-Micromolar and Broad Spectrum Antitrypanosomal Activities
- Tryp: a dataset of microscopy images of unstained thick blood smears for trypanosome detection
- Trypanocide usage in the cattle belt of southwestern Uganda
- Trypanosoma brucei gambiense group 2 experimental in vivo life cycle: from procyclic to bloodstream form
- Trypanosoma brucei proliferates normally even after losing all S-adenosylhomocysteine hydrolase genes
- Trypanosome diversity in small mammals in Uganda and the spread of Trypanosoma lewisi to native species
- Unique Interactions of the Small Translocases of the Mitochondrial Inner Membrane (Tims) in <em>Trypanosoma brucei</em>
- Using Passive Surveillance to Maintain Elimination as a Public Health Problem for Neglected Tropical Diseases: A Model-Based Exploration
- Virulence and pathogenicity of three <em>Trypanosoma brucei rhodesiense</em> stabilates in a Swiss white mouse model