SAN DIEGO, Calif. — Avidity Biosciences, Inc. (Nasdaq: RNA), a biopharmaceutical company committed to delivering a new class of RNA therapeutics called Antibody Oligonucleotide Conjugates (AOCs™) to profoundly improve people’s lives, today announced that it will deliver late-breaking oral and poster presentations at the 30th Annual International Congress of the World Muscle Society (WMS), to be held October 7-11, 2025, in Vienna, Austria.
The data to be presented at WMS will reinforce and build on the positive data announced by Avidity in September 2025 which showed reversal of disease progression and unprecedented improvement compared to baseline and natural history across multiple functional measures for participants living with Duchenne muscular dystrophy mutations amenable to exon 44 skipping (DMD44) treated continuously with delpacibart zotadirsen (del-zota) for one year in the Phase 1/2 EXPLORE44® and Phase 2 EXPLORE44-OLE™ trials. Del-zota is investigational, and it is not approved by the FDA. Its safety and efficacy have not been established.
30th Annual World Muscle Society Congress Presentations
- Delpacibart zotadirsen (del-zota) showed trends toward improvement in functional and patient-reported outcomes in individuals with DMD amenable to exon 44 skipping
- Oral presentation: Kevin M. Flanigan, M.D., Nationwide Children’s Hospital, to present on October 11, 2025, from 12:33 – 12:45 p.m. CET
- Delpacibart Zotadirsen (Del-zota) Increased Dystrophin and Improved Muscle Integrity Markers Regardless of Ambulatory Status in Individuals with DMD44
- Poster presentation (674P): Aravindhan Veerapandiyan, M.D., Associate Professor of Pediatrics, University of Arkansas for Medical Sciences and Arkansas Children’s Hospital, to present on October 8, 2025, from 2:30 – 3:30 p.m. CET
The presentation and poster will be available on the publications page of Avidity’s website at https://www.aviditybiosciences.com.
About Avidity
Avidity Biosciences, Inc.’s mission is to profoundly improve people’s lives by delivering a new class of RNA therapeutics – Antibody Oligonucleotide Conjugates (AOCs™). Avidity is revolutionizing the field of RNA with its proprietary AOCs, which are designed to combine the specificity of monoclonal antibodies with the precision of oligonucleotide therapies to address targets and diseases previously unreachable with existing RNA therapies. Utilizing its proprietary AOC platform, Avidity demonstrated the first-ever successful targeted delivery of RNA into muscle and is leading the field with clinical development programs for three rare muscle diseases: myotonic dystrophy type 1 (DM1), Duchenne muscular dystrophy (DMD) and facioscapulohumeral muscular dystrophy (FSHD). Avidity is also advancing two wholly-owned precision cardiology development candidates addressing rare genetic cardiomyopathies. In addition, Avidity is broadening the reach of AOCs with its advancing and expanding pipeline including programs in cardiology and immunology through key partnerships. Avidity is headquartered in San Diego, CA. For more information about our AOC platform, clinical development pipeline and people, please visit www.aviditybiosciences.com and engage with us on LinkedIn and X.
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