Yunis Varon syndrome

Overview

Yunis Varon syndrome is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Yunis Varon syndrome, or a subtype of Yunis Varon syndrome, affects less than 200,000 people in the US population.

Yunis Varon Syndrome is an extremely rare autosomal recessive inherited multisystem disorder with defect affecting the skeletal, ectodermal and cardiorespiratory system.

Symptoms

The striking charateristics are:

• prenatal and postnatal growth deficiency
• defective growth of bones of the skull
• complete or partial absence of clavicles (cleidocranialdysplasia)
• charateristic facial features
• hypoplasia or absence of thumbs
• big toes
• distal aphalangea

Diagnosis

The phrase "signs of Yunis Varon syndrome" should, strictly speaking, refer only to those signs and symptoms of Yunis Varon syndrome that are not readily apparent to the patient.