Sinus histiocytosis
Overview
Sinus histiocytosis: Another name for Rosai-Dorfman disease (or close medical condition association). Rosai-Dorfman disease: A rare condition characterized by excessive production and accumulation of a particular white blood cell (histiocyte). Accumulation primarily occurs in the lymph nodes, especially in the neck, but may also occur in the skin, central nervous system, digestive tract and kidneys.
Symptoms
The list of signs and symptoms mentioned in various sources for Rosai-Dorfman disease includes the 21 symptoms listed below: * Enlarged lymph nodes * Enlarged liver * Enlarged spleen * Fever * Pallor * Anemia * Rheumatic symptoms * Weight loss * Tonsillitis * Nasal discharge * Nasal obstruction * White blood cell accumulation in skin * White blood cell accumulation in lung * White blood cell accumulation in bone * White blood cell accumulation in eye orbits * White blood cell accumulation in eyelids * White blood cell accumulation in kidneys * White blood cell accumulation in peritoneum * White blood cell accumulation in testes * White blood cell accumulation in central nervous system * White blood cell accumulation in digestive tract Note that Rosai-Dorfman disease symptoms usually refers to various symptoms known to a patient, but the phrase Rosai-Dorfman disease signs may refer to those signs only noticable by a doctor.
Causes
Other Possible Causes of these Symptoms * Anemia * Enlarged liver * Enlarged lymph nodes * Enlarged spleen * Fever * Nasal obstruction * Pallor * Tonsillitis * Weight loss
Diagnosis
The signs and symptom information on this page attempts to provide a list of some possible signs and symptoms of Rosai-Dorfman disease. This medical information about signs and symptoms for Rosai-Dorfman disease has been gathered from various sources, may not be fully accurate, and may not be the full list of Rosai-Dorfman disease signs or Rosai-Dorfman disease symptoms. Furthermore, signs and symptoms of Rosai-Dorfman disease may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they are indeed Rosai-Dorfman disease symptoms.