Rosenberg Chutorian syndrome
Overview
A very rare disorder involving eye, ear and nerve disorders.
Symptoms
* Distal muscular atrophy * Progressive optic atrophy * Hearing loss * Loss of vision * Polyneuropathy of limbs * Optic atrophy * Peripheral neuropathy * Reduced sensation in hands * Reduced sensation in feet * Impaired color vision * Reduced pain sensation
Causes
Other causes include retinitis pigmentosa; chronic papilledema and papillitis; glaucoma; trauma; central retinal artery or vein occlusion that interrupts the blood supply to the optic nerve, causing degeneration of ganglion cells; ingestion of toxins, such as methanol and quinine; and deficiencies of vitamin B 12, amino acids, and zinc.
Treatment
Optic atrophy is irreversible, so treatment aims to correct the underlying cause and prevent further vision loss. Steroids may be given to decrease inflammation and swelling, if the cause is found to be ischemic neuropathy. If a space-occupying lesion is the cause, neurosurgery may be required. In multiple sclerosis , optic neuritis often subsides spontaneously but may recur and improve repeatedly.