Ossification of the posterior longitudinal ligament of the spine

Overview

Abnormal calcification of a spinal ligament. The progressive calcification can starts within months of birth and affects the ability to move arms and legs. The severity of the condition is highly variable with most patients noticing symptoms in the sixth decade

Symptoms

* Sensory dysfunction in limbs * Motor dysfunction in limbs * Bladder dysfunction * Abnormal reflexes * Clumsiness

Causes

* Abuse dwarfism syndrome * Acanthocytosis * Aceruloplasminemia * Acid-Base Imbalance * Acquired angioedema